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In Development this week (Vol. 138, Issue 2)

Posted by on December 21st, 2010

Boning up on stem cell Igf2-P2 function The insulin-like growth factor (IGF)/insulin signalling pathway regulates cell proliferation, differentiation, aging and life span. During embryonic development, transcription of the mouse and human Igf2 gene is tightly regulated by four alternative promoters whose specific roles are unclear. Now, Sylvie Nathalie Hardouin and colleagues reveal that the transcriptional[…]