the community site for and by developmental biologists
the community site for and by developmental biologists
Posted by odedm on November 15th, 2018
Newborn babies are a symbol of immense potential, as they can grow up to be become virtually anybody, from an astronaut to the president. It is no secret that throughout life, there are critical junctions in which specific events or decisions can direct us on one path or another. Such events occur in our brains;[…]
Posted by JNMalagon on November 14th, 2018
Juan N. Malagon and Ernest Ho tell the story behind their recent paper in PLOS Computational Biology. In the Larsen lab, we are interested in testing a 50-year old question: How do sex combs rotate in fruit flies? Despite extensive studies of the process using 4D confocal microscopy, there remain many questions about the spatial and[…]
Posted by kgrobe on October 18th, 2018
1 PhD Position : Characterization of Hedgehog morphogens in vitro and in vivo Hedgehog (Hh) morphogens play important roles in development and cancer, but their mode of extracellular transport to target cells is only poorly understood. Thus, we aim at the characterization of various unusual posttranslational regulatory mechanisms in Hh biology, such as Hh multimerization[…]
Posted by IRBBarcelona on September 26th, 2018
Most solid tumours with metastatic potential show a high degree of chromosomal instability. A study published in the journal Developmental Cell demonstrates that chromosomal instability itself promotes invasive behaviour. The researchers identify the oncogene Fos and the tumour suppressor Capicua as necessary molecular elements mediating this invasive behaviour. Barcelona, 26 September 2018.- Metastatic tumours are[…]
Posted by Andreas Prokop on September 6th, 2018
BBSRC funded postdoc position in the laboratory of Natalia Sánchez-Soriano (https://sanchezlab.wordpress.com), to study the cell biology of neuronal ageing and the underlying mechanisms. On this project you will study the harmful changes that neurons undergo at the subcellular level during ageing, and unravel the cascade of events that cause them. The focus will[…]
Posted by the Node Interviews on September 4th, 2018
Axon guidance relies on the reception and integration of molecular cues from the environment by growth cones, and defective pathfinding results in misplaced projection patterns in the mature nervous system. A new paper in Development investigates this process in the Drosophila neuromucular system, as well as the consequences of axonal miswiring to locomotion. We caught up[…]
Posted by dbsste on August 23rd, 2018
It’s an age-old mystery of the heart: do opposites attract, or will like do better with like? We can now answer this pressing question, at least for Drosophila cardioblasts: cells prefer to ‘swipe right’ on a shared transcriptional profile, but the resulting relationships are stronger if there are some unattractive alternatives around to remind them[…]
Posted by Matthew R Johnson on August 21st, 2018
All life requires energy. For early metazoan development, demand is especially high, as the transition from a single cell to a complex, multicellular organism requires a massive energetic input. In the earliest stages of development, however, an organisms’ inability to feed poses an apparent problem: how is the energy necessary to drive development obtained? In[…]
Posted by Scutoids on August 3rd, 2018
In LM Escudero´s group, we like developmental biology, mathematical biology and computational biology. We try to be imaginative and get inspiration from simple things… such as a toilet paper roll. Using this tool (and some computers), we claim that we have described a novel geometrical shape… You will be wondering… how do you do[…]
Posted by Stephanie Mohr on June 27th, 2018
The DRSC/TRiP Functional Genomics Resources in the Perrimon group at Harvard Medical School in Boston, MA, USA, is seeking a highly motivated senior-level research technician to join our team. The successful candidate will be responsible for performing molecular biology, cell culture, protein purification, and/or related techniques as part of an overall research program focused on[…]
