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Displaying posts with the tag: drosophila [Clear Filter]

Senior Research Position (Boston, MA)

Posted by on June 27th, 2018

The DRSC/TRiP Functional Genomics Resources in the Perrimon group at Harvard Medical School in Boston, MA, USA, is seeking a highly motivated senior-level research technician to join our team. The successful candidate will be responsible for performing molecular biology, cell culture, protein purification, and/or related techniques as part of an overall research program focused on[…]

BBSRC-funded postdoc position – neuronal ageing

Posted by on June 26th, 2018

BBSRC funded postdoc position in the laboratory of Natalia Sanchez-Soriano (https://sanchezlab.wordpress.com), to study the cell biology of neuronal ageing and the underlying mechanisms.  The aim of the project is to understand the harmful changes that neurons undergo at the subcellular level during ageing, and unravel the cascade of events that cause them, with a focus[…]

Lighting Up the Central Dogma in Development

Posted by on June 19th, 2018

We recently published a manuscript in Cell that describes a method to image transcription factor concentration dynamics in real time, in living embryos, using a nanobody-based protein tag that we call the “LlamaTag.” We were particularly excited about these investigations because this new technology overcomes a major technical obstacle to understanding how gene-expression dynamics are[…]

From basic questions to exciting findings

Posted by on May 21st, 2018

In this post we report the backstories behind our recently published paper. It was an enjoyable research adventure driven by discussions, readings, exciting experiments and unexpected discoveries. As a result, we described a novel molecular mechanism underpinning stem cell and progenitor maintenance during development. Here is the sequence of the main events that inspired us[…]

Redefining the Aging Process

Posted by on May 4th, 2018

This post highlights the approach and findings of a new research article published in Disease Models and Mechanisms (DMM). This feature was written by J. Brucker Nourse Jr. as part of a graduate level seminar at The University of Alabama (taught by DMM Editorial Board member, Prof. Guy Caldwell) on current topics related to use[…]

PhD position: Chromosome Dynamics During Spermatogenesis in Drosophila, University of Zurich, Switzerland

Posted by on April 19th, 2018

We seek candidates interested in completing a PhD thesis within the framework of a research project (46 months) funded by the Swiss National Science Foundation (SNF). Chromosome reorganization during spermatogenesis is dramatic. Beyond meiosis, it includes chromosome compaction into an elongated sperm nucleus which is accompanied by an almost complete exchange of histones with sperm[…]

postdoctoral fellow position: Hedgehog control of neuronal activity.

Posted by on April 19th, 2018

We invite applications for a postdoctoral position to join a multidisciplinary project in the Alenius group at Umeå university. The project is based on our recent discovery that Hedgehog control neuronal activity in both Drosophila and mouse1. 2  The approach is to combine Drosophila genetics, biochemistry with imaging in order to investigate the fundamental mechanisms that control[…]

The people behind the papers – Jinjin Zhu & Justin Kumar

Posted by on April 9th, 2018

Cell fate commitment relies on both activation of appropriate genes and suppression of inappropriate ones. Polycomb group proteins are known to be crucial epigenetic silencers of developmental genes, but the manner by which they control fate in vivo, and the relative roles of different Polycomb proteins in silencing, have remained unclear. A new paper in Development[…]

The people behind the papers – Rémi-Xavier Coux & Ruth Lehmann

Posted by on April 5th, 2018

Development and homeostasis depend crucially on the maintenance of cell identity, and in gamete-producing tissues the somatic/germline distinction is paramount. A recent paper in Development explores how cell identity is secured in the Drosophila ovary by studying the function of the conserved tumour suppressor L(3)mbt. To find out more about the story, we caught up with first author Rémi-Xavier[…]

PhD project on membrane trafficking dynamics during epithelial polarization

Posted by on April 3rd, 2018

The newly established Collaborative Research Center 1348 “Dynamic Cellular Interfaces: Formation and Function” at the University of Münster, Germany, invites applications for a   PhD Position (salary level 13 TV-L, 65%) in the area of Membrane trafficking dynamics during epithelial polarization This fixed-term position is available from the earliest possible date for three years. The[…]