the community site for and by developmental biologists
the community site for and by developmental biologists
Posted by Hadi Boukhatmi on May 21st, 2018
In this post we report the backstories behind our recently published paper. It was an enjoyable research adventure driven by discussions, readings, exciting experiments and unexpected discoveries. As a result, we described a novel molecular mechanism underpinning stem cell and progenitor maintenance during development. Here is the sequence of the main events that inspired us[…]
Posted by J. Brucker Nourse Jr. on May 4th, 2018
This post highlights the approach and findings of a new research article published in Disease Models and Mechanisms (DMM). This feature was written by J. Brucker Nourse Jr. as part of a graduate level seminar at The University of Alabama (taught by DMM Editorial Board member, Prof. Guy Caldwell) on current topics related to use[…]
Posted by Christian Lehner on April 19th, 2018
We seek candidates interested in completing a PhD thesis within the framework of a research project (46 months) funded by the Swiss National Science Foundation (SNF). Chromosome reorganization during spermatogenesis is dramatic. Beyond meiosis, it includes chromosome compaction into an elongated sperm nucleus which is accompanied by an almost complete exchange of histones with sperm[…]
Posted by alenius on April 19th, 2018
We invite applications for a postdoctoral position to join a multidisciplinary project in the Alenius group at Umeå university. The project is based on our recent discovery that Hedgehog control neuronal activity in both Drosophila and mouse1. 2 The approach is to combine Drosophila genetics, biochemistry with imaging in order to investigate the fundamental mechanisms that control[…]
Posted by the Node Interviews on April 9th, 2018
Cell fate commitment relies on both activation of appropriate genes and suppression of inappropriate ones. Polycomb group proteins are known to be crucial epigenetic silencers of developmental genes, but the manner by which they control fate in vivo, and the relative roles of different Polycomb proteins in silencing, have remained unclear. A new paper in Development[…]
Posted by the Node Interviews on April 5th, 2018
Development and homeostasis depend crucially on the maintenance of cell identity, and in gamete-producing tissues the somatic/germline distinction is paramount. A recent paper in Development explores how cell identity is secured in the Drosophila ovary by studying the function of the conserved tumour suppressor L(3)mbt. To find out more about the story, we caught up with first author Rémi-Xavier[…]
Posted by luschnig on April 3rd, 2018
The newly established Collaborative Research Center 1348 “Dynamic Cellular Interfaces: Formation and Function” at the University of Münster, Germany, invites applications for a PhD Position (salary level 13 TV-L, 65%) in the area of Membrane trafficking dynamics during epithelial polarization This fixed-term position is available from the earliest possible date for three years. The[…]
Posted by Jun Chen on March 6th, 2018
Jun Chen National Institute of Biological Sciences, Beijing A discussion of our recent paper: Chen J, Xu N, Wang C, Huang P, Huang H, Jin Z, Yu Z, Cai T, Jiao R, Xi R. Transient Scute activation via a self-stimulatory loop directs enteroendocrine cell pair specification from self-renewing intestinal stem cells. Nat Cell Biol. 2018[…]
Posted by Alex Gould on February 20th, 2018
An exciting opportunity to be part of a pioneering biomedical research institute, dedicated to innovation and science. A postdoctoral research post in the laboratory of Dr. Alex P. Gould is now available. We are looking for a highly motivated researcher to identify the, as yet unknown, molecular mechanisms by which dietary nutrients and oxidative stress[…]
Posted by Charlotte Blackburn on February 20th, 2018
The droso4schools initiative is an educational outreach programme run by the Manchester Fly Facility, which I had the opportunity to be actively involved in during a month-long placement (see my previous blog). The aim of this programme is to re-introduce the fruit fly Drosophila melanogaster into school and college biology lessons. For this, the droso4schools[…]
