the community site for and by developmental biologists
the community site for and by developmental biologists
Posted by Andreas Prokop on October 17th, 2017
The University of Manchester, 2018/19 BBSRC DTP PhD Project Understanding tubulin regulation during neuronal development, ageing and degeneration Axons are slender, up-to-a-meter long, cable-like extensions of neurons which form the nerves and nerve tracts that wire our bodies and brain. These delicate cellular structures have to be maintained for an organism’s life time and are[…]
Posted by Dai Jianli on October 16th, 2017
The Great Wall of Collagen IV During the long history of evolution, the key innovation that gave rise to animals with true tissues was the extracellular matrix, very conserved from sponges to humans [1]. Before I started my PhD in the lab of Jose C. Pastor-Pareja at Tsinghua University in Beijing, he had described how[…]
Posted by jasminalsous on September 19th, 2017
A post by Jasmin Imran Alsous, on work done in collaboration with Paul Villoutreix and Alexander M. Berezhkovskii in the Shvartsman lab. I started working on Drosophila egg chambers from the day I joined the Shvartsman lab. Egg chambers are small clusters of cells that eventually develop into mature oocytes in the abdomen of the female[…]
Posted by IRBBarcelona on September 8th, 2017
Researchers from the Development and Growth Control Laboratory at IRB Barcelona have identified the cell types and molecular mechanism responsible for the unlimited growth potential of epithelial tumours (carcinomas) and demonstrated that the growth of these tumours is independent of its microenvironment. “In epithelial tumours caused by chromosomal instability or loss of cell polarity, the[…]
Posted by luschnig on August 26th, 2017
The Cluster of Excellence ”Cells in Motion“ (CiM) at the University of Münster invites applications for a PhD student position (Salary Scale 13 TV-L / 65%) on Cellular dynamics during epithelial morphogenesis in Drosophila in the group of Prof. Stefan Luschnig at the Institute of Neurobiology. The position is available from[…]
Posted by Matt Niederhuber on August 8th, 2017
Each of our cells has the same genetic information and thus the same potential to become a part of a heart, brain, or a finger. Somehow though, during development our cells manage to figure out exactly which type of cell they should be and which body parts they should help compose. The key to making[…]
Posted by kyracampbell on August 3rd, 2017
A Wellcome Trust/Royal Society funded Research Assistant position is available in Dr Kyra Campbell’s research group. This is a fantastic opportunity to join the Campbell group, who are focused on identifying the molecular mechanisms underlying epithelial cell plasticity during development and disease. We study how this fundamental property is orchestrated during morphogenesis of the Drosophila[…]
Posted by the Node Interviews on August 2nd, 2017
Ion channels are famous for their roles in neurons and muscles, but the spectrum of phenotypes seen in ion channel mutants indicate a diversity of roles in development; the underlying mechanisms, however, have remained opaque. This week we feature a paper published in the latest issue of Development that reveals a link between potassium channels and morphogen[…]
Posted by IRBBarcelona on July 5th, 2017
• Scientists at IRB Barcelona clarify the function of the genes that drive wing development in the fruit fly Drosophila melanogaster. • Published in the journal eLife, this study unveils that the Dpp morphogen is necessary for wing growth but that its gradient does not govern this process. • Understanding the development of limbs in[…]
Posted by areilein on June 16th, 2017
A discussion of “Alternative direct stem cell derivatives defined by stem cell location and graded Wnt signalling,” Nat Cell Biol, 2017. 19(5): p. 433-444. We have recently revised the model of Follicle Stem Cell (FSC) organization in the Drosophila ovary, showing that there is a much larger population of stem cells than formerly realized, that[…]
