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Displaying posts with the tag: mouse-development [Clear Filter]

An interview with Jenny Nichols

Posted by on August 17th, 2017

This interview by Aidan Maartens originally appeared in Development, Volume 143, Issue 16. Jennifer Nichols is a Principal Investigator at the Cambridge Stem Cell Institute and Department of Physiology, Development and Neuroscience at the University of Cambridge, UK. Her lab works on lineage segregation and the establishment of pluripotency in the mammalian embryo. In 2017 she was[…]

The forces that shape us: Mechanics of mammalian neural tube morphogenesis

Posted by on July 7th, 2017

Introduction to the biomechanics of neurulation Those of us who go to the gym are accustomed to thinking of mechanical forces shaping our bodies. Physiological (e.g. determination of bone mass and architecture), pathological (e.g. aneurysm rupture) and even socio-cultural (e.g. lip plates of the Mursi tribe) examples come to mind. The form of most of[…]

eLearning at eMouseAtlas

Posted by on November 24th, 2016

A new eLearning resource that provides short and interactive vignettes in embryo (primarily vertebrate) development, from gametogenesis through to organogenesis, is available from the eMouseAtlas1,2 website (www.emouseatlas.org). The current eLearning content are the tutorials produced by Professor José García Monterde of the University of Córdoba, and the presentation from collaboration between Professor Monterde and the[…]

Electrifying news for embryologists

Posted by on June 17th, 2014

Electroporation: an efficient technique for embryologists During embryonic development, the specification of different cell types giving rise to the future organs involves a precise spatiotemporal regulation of cell proliferation, migration, and differentiation. Studying these processes requires tools to manipulate gene expression locally in the developing embryo.To this aim, embryologists have widely used the technique of[…]

GATA6 and the power of single cells

Posted by on May 29th, 2014

Any mammal who celebrated Mother’s Day earlier this month realizes how important mothers are for us and the tight bond between them and their children. Forget clean shirts and packed lunch every day; for us developmental biologists, there is no better reflection of this bond than the extraembryonic membranes that support the growth of the[…]

An interview with Patrick Tam

Posted by on November 25th, 2010

(This interview by Kathryn Senior originally appeared in Development on November 23, 2010) Patrick Tam’s research is focused on the cellular and molecular mechanisms of body patterning during mouse development. He agreed to be interviewed by Development to talk about his interest in mouse development, new concepts in gastrulation, X-linked diseases and his dream of[…]