the community site for and by developmental biologists

Displaying posts with the tag: transposon [Clear Filter]

Silencing transposons during epigenetic reprogramming

Posted by on November 8th, 2017

Molecules called endosiRNAs help us avoid genetic chaos, according to a new study from a team at the Babraham Institute. Much of the human genome contains pieces of DNA called transposons, a form of genetic parasite. When active, transposons can damage genes so it is important to keep them inactive. At a certain point early[…]

Transposons in Embryo Space – TRACER maps in EMAGE

Posted by on February 9th, 2017

A recent publication in Developmental Biology by (Armit et al., 2017) describes how the TRACER dataset can be spatially compared with in situ hybridisation gene expression profiles.   The TRACER dataset of transposon-associated regulatory sensors (Chen et al., 2013) utilises Sleeping Beauty lacZ transposons that have been randomly integrated into the mouse genome Hundreds of[…]