the community site for and by developmental biologists

Displaying posts with the tag: zebrafish [Clear Filter]

The people behind the papers: Gabriel Krens and Carl-Philipp Heisenberg

Posted by on May 25th, 2017

Cell sorting is a critical process during development, as differently specified cells are segregated to the right parts of the embryo. Differences in cell adhesion and cortical tension are thought to be crucial to this process, but the mechanics have been difficult to probe in vivo. This week’s paper, published in the current issue of[…]

Biotagging: Behind the scenes (and beyond)

Posted by on May 16th, 2017

“It finally got accepted!”, fol­­lowed by “It’s finally out!” about a month later. I am certain this ‘finally’ feeling about their paper is very familiar to those well-acquainted with the peer review process, and it was no different for our recently published Resource article. The ‘biotagging paper’, as we call it within the Sauka-Spengler lab,[…]

The people behind the papers: Dae Seok Eom & David Parichy

Posted by on April 7th, 2017

Macrophages are usually associated with immunity, but have increasingly appreciated functions in development and homeostasis. This week we meet the authors of a recent Science paper that identified a role for macrophages in zebrafish stripe patterning, revealing a remarkable ‘relay’ mechanism whereby macrophages help one type of cell signal to another via cytoplasmic extensions. Postdoc[…]

Biologists find ‘skin-and-bones’ mechanism underlying zebrafish fin regeneration

Posted by on March 28th, 2017

This Press Release from the University of Oregon was originally posted on Eurekalert.   EUGENE, Ore. March 28, 2017 University of Oregon biologists have figured out how zebrafish perfectly regenerate amputated fins with a precisely organized skeleton. Adult zebrafish fins, including their complex skeleton, regenerate exactly to their original form within two weeks after an[…]

New signal revealed for birth of blood stem cells in vertebrates

Posted by on March 1st, 2017

Jamie R. Genthe and Wilson K. Clements   When blood goes bad, a replacement is often needed. Each year, thousands of patients in the US receive bone marrow transplants to treat life-threatening diseases like blood cancer. But in some cases, the transplant itself can become deadly. The problem is not necessarily the one most people think[…]

Diversity is a good thing: coordination of collective cell migration in angiogenesis

Posted by on February 2nd, 2017

Comment on “Asymmetric division coordinates collective cell migration in angiogenesis” Nat Cell Bio, 18 (12), 1292-1301, (2016).   Holly E. Lovegrove & Guilherme Costa Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, Uk   Collective cell migration is involved in many biological processes. In particular it is required to build new tissues[…]

The tale of three cities – Valdivia, Jyväskylä and London

Posted by on January 23rd, 2017

This is the latest dispatch from a recipient of a Company of Biologists Travelling Fellowship. Learn more about the scheme, including how to apply, here, and read more stories from the Fellows here. Hanna Hakkinen   I am originally a Finnish evolutionary biology student who got fascinated about developmental biology during my exchange programme couple of[…]

The people behind the papers: James Nichols

Posted by on November 29th, 2016

Today’s paper comes from the latest issue of Development, and reveals a link between phenotypic variability, cell fate switching and epigenetic silencing in zebrafish. Lead author James T. Nichols, who carried out the work in Charles Kimmel’s lab in Euegene, Oregon and is now an Assistant Professor in UC Denver’s School of Dental Medicine, gave us the story behind[…]

Postdoctoral position in muscle biology

Posted by on October 18th, 2016

Postdoctoral position in muscle biology At the Dept of Clinical Sciences, Umeå University, Sweden Project description: The selected candidate will work within the research project ”The molecular portfolio of the extraocular muscles”, led by Professor Fatima Pedrosa Domellöf at the Departments of Clinical Sciences at Umeå University, Sweden. The actual research project explores i) how[…]

Where does blood come from in the first place and how is it made?

Posted by on September 14th, 2016

Commentary on Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells in Developmental Cell, Volume 38, Issue 4, p358–370, 22 August 2016   Each of us has around 6 pints of blood. The blood contains a number of different types of cells, including oxygen-transporting red blood cells, disease-protecting white[…]