the community site for and by developmental biologists

Call for Papers: a Special Collection on Neurodegenerative Diseases

Posted by on May 31st, 2016

Disease Models & Mechanisms invites you to submit original research for consideration for an upcoming Special Collection ‘Neurodegeneration: From Models to Mechanisms to Therapies‘. This ongoing collection will focus on mechanistic insights into neurodegenerative diseases using model systems, with an emphasis on key translational advances made in recent years. This collection will be launched with[…]

In Development this week (Vol. 143, Issue 11)

Posted by on May 31st, 2016

Here are the highlights from the current issue of Development:   A new paradigm for Wnt/β-catenin signalling The Wnt/β-catenin signalling pathway is a key pathway involved in a myriad of developmental processes, from body axis patterning to cell migration and fate specification. The role of the Wnt pathway is to regulate transcription of specific target[…]

Question of the month – the 14 day rule for human embryo research

Posted by on May 31st, 2016

Earlier this month, two papers were published (from the Brivanlou and Zernicka-Goetz labs) that reported in vitro systems to study development of the human embryo through implantation stages. These experiments have kept human embryos developing for longer than any previous work, and close in on the 14-day limit imposed by many governmental and regulatory bodies.[…]

Postdoctoral fellow in mammary gland biology and breast cancer

Posted by on May 30th, 2016

A position for a postdoctoral fellow (2 years of funding) is available in the group of Renee van Amerongen at the University of Amsterdam, the Netherlands to study mammary gland development. Mammalian development and tissue homeostasis are complex and dynamic biological processes. Focusing on Wnt signal transduction, our research aims to understand the genetic and[…]

Development meeting: From stem cells to human development

Posted by on May 27th, 2016

In September, Development will be holding the second of our ‘From stem cells to human development‘ meetings – following on from the hugely successful first event in Autumn 2014 (see here and here). This year’s meeting promises to be equally exciting, with a fantastic line-up of speakers (check out the preliminary program) and a great venue just[…]

Geometrical models of tissue as tools for uncovering rules underlying tissue organization

Posted by on May 27th, 2016

A major challenge in cell and developmental biology is to understand the mechanisms whereby cells interact with each other to form the variety of complex tissue forms present in organisms. This requires visualizing and analysing different cellular processes across multiple scale levels -from the subcellular to the tissue, i.e. generating cell and tissue models at[…]

New insights into sex differences in Drosophila development and physiology

Posted by on May 27th, 2016

Bruno Hudry and Elizabeth J. Rideout Male and female fruit flies differ in many aspects of development and physiology. For example, males and females differ in abdominal pigmentation, sex comb formation, courtship behaviours, the development and wiring of the central nervous system, internal reproductive organs, and genital morphology. Many elegant studies on the genes that[…]

From our sister journals – May 2016

Posted by on May 26th, 2016

Here is some developmental biology related content from other journals published by The Company of Biologists.           Gastrointestinal stem cells in health and disease This Review from Li and Jasper highlights recent findings on intestinal stem cell (ISC) diversity in the GI tract of Drosophila, focusing on the role of ISCs in[…]

Fueling embryology and developing metabolism

Posted by on May 25th, 2016

By Carlos Carmona-Fontaine and Patricia Nunes   Most scientific conferences have become large gatherings where little exchange of ideas can actually occur. There are way too many people to start socializing with folks you don’t know and there are so many talks that the idea of sitting through one on a topic on which you[…]

2 technical and 1 post-doctoral posts in cell biology, molecular endocrinology and skeletal biology, Imperial College London

Posted by on May 24th, 2016

Professors Graham Williams and Duncan Bassett have 3 full-time posts (5 years each) available. One technical post in skeletal biology is funded by the Horizon 2020 grant: Resetting the THYRoid axis for prevention of AGE-related diseases and co-morbidities. One post-doc and one technician post in molecular and cellular biology are funded by the Wellcome Trust:[…]