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September in preprints

Posted by , on 9 October 2024

Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints.

The preprints this month are hosted on bioRxiv and arXiv – use these links below to get to the section you want:

Developmental biology

Cell Biology

Modelling

Tools & Resources

Research practice and education

Developmental biology

| Patterning & signalling

Wnt5a and Notum Influence the Temporal Dynamics of Cartilaginous Mesenchymal Condensations in Developing Trachea

Natalia Bottasso-Arias, Megha Mohanakrishnan, Sarah Trovillion, Kaulini Burra, Nicholas X. Russell, Yixin Wu, Yan Xu, Debora Sinner

Melastatin subfamily Transient Receptor Potential channels support spermatogenesis in planarian flatworms

Haley Nicole Curry, Roger Huynh, Labib Rouhana

Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development

Rebecca Armstrong, Nikki J Marks, Timothy G Geary, John Harrington, Paul M Selzer, Aaron G Maule

Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs

Rocío Hernández-Martínez, Sonja Nowotschin, Luke T.G. Harland, Ying-Yi Kuo, Bart Theeuwes, Berthold Göttgens, Elizabeth Lacy, Anna-Katerina Hadjantonakis, Kathryn V. Anderson

Developmental Effects of Lithium and Zinc in Planaria

Alberto Molano

Three waves of ovarian follicles in juvenile mice

Qi Yin, Allan C Spradling

Cardiac Fibroblasts regulate myocardium and coronary vasculature development via the collagen signaling pathway

Yiting Deng, Yuanhang He, Juan Xu, Haoting He, Manling Zhang, Guang Li

Cell type and cell signaling innovations underlying mammalian pregnancy

Daniel J. Stadtmauer, Silvia Basanta Martínez, Jamie D. Maziarz, Alison G. Cole, Gülay Dagdas, Gilbecca Rae Smith, Frank van Breukelen, Mihaela Pavličev, Günter P. Wagner

Phosphorylation-induced SUMOylation promotes Ulk4 condensation at ciliary tip to transduce Hedgehog signal

Mengmeng Zhou, Yuhong Han, Jin Jiang

Non-cell-autonomous control of gastruloid development by the lncRNA T-UCstem1 through DKK1-dependent modulation of WNT signalling

Arianna Coppola, Filomena Amoroso, Federica Saracino, Gennaro Andolfi, Edoardo Sozzi, Paolo Salerno, Pietro Zoppoli, Alessandro Fiorenzano, Giuseppe Merla, Eduardo Jorge Patriarca, Gabriella Minchiotti, Annalisa Fico

Human macula formation involves two waves of retinoic acid signaling suppression via CYP26A1 regulating cell cycle exit and cone specification

Philippa Harding, Maja Wojtynska, Alexander J. Smith, Robin R. Ali, Rachael A. Pearson

The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development

Stanley M. Kanai, Chloe R. Garcia, MaCalia R. Augustus, Shujan A. Sharafeldeen, Elliott P. Brooks, Juliana Sucharov, Ezra S. Lencer, James T. Nichols, David E. Clouthier

Notch/Hairless Pathway Modulation of sog Transcriptional Bursting in Prelude to Gastrulation

Kelli D. Fenelon, Priyanshi Borad, Biraaj Rout, Parisa Boodaghimalidarreh, Mohammad S. Nasr, Jacob Luber, Theodora Koromila

Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila

Jyoti Singh, Dipti Verma, Bappi Sarkar, Maimuna Sali Paul, Mousumi Mutsuddi, Ashim Mukherjee

From Singh et al. This image is made available under a CC-BY 4.0 International license.

YAP/TAZ signaling in allantois-derived cells is required for placental vascularization

Siqi Gao, Triloshan Thillaikumaran, Martin H. Dominguez, William Giang, Kevin Hayes, Xiaowen Chen, Jesse Pace, Jenna Bockman, Danielle Jathan, Derek Sung, Sweta Narayan, Maxwell Frankfurter, Patricia Mericko-Ishizuka, Jisheng Yang, Marco Castro, Michael Potente, Mark L. Kahn

Spatiotemporal Patterns of Gene Expression During Development of a Complex Colony Morphology

Gareth A. Cromie, Zhihao Tan, Michelle Hays, Amy Sirr, Aimée M. Dudley

Somatic Transthyretin-Related Proteins in C. elegans Govern Reproductive Longevity by Sustaining Sperm Integrity and Timely Ovulation

Tingshan Wu, Haochen Lyu, Zhao Wang, Zhaoyang Jiang, Yingchuan B. Qi

Dynamic BMP signaling regulates sclerotome induction and lineage diversification in zebrafish

Linjun Xie, Roger C. Ma, Katrinka M. Kocha, Emilio E. Méndez-Olivos, Peng Huang

AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth

Yann Cormerais, Samuel C. Lapp, Krystle C. Kalafut, Madi Y. Cissé, Jong Shin, Benjamin Stefadu, Jean Personnaz, Sandra Schrotter, Angelica D’Amore, Emma R. Martin, Catherine L. Salussolia, Mustafa Sahin, Suchithra Menon, Vanessa Byles, Brendan D. Manning

| Morphogenesis & mechanics

Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin

Fereshteh Sadeghian, Noa W.F. Grooms, Samuel H. Chung, Erin J. Cram

Highly dynamic mechanical transitions in embryonic cell populations during Drosophila gastrulation

Juan Manuel Gomez, Carlo Bevilacqua, Abhisha Thayambath, Maria Leptin, Julio M Belmonte, Robert Prevedel

Mast cells are not essential for pubertal mammary gland branching

Simran Kapoor, Jimmy Marsden, Clara M. Munz, Cyril Carvalho, Marlene Magalhaes Pinto, Bert Malengier-Devlies, Solvig Becker, Guillaume Seuzaret, Katelyn Patatsos, Ramazan Akyol, Marc Dalod, Amy Pedersen, Gillian Wilson, Rebecca Gentek

Nodal Modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation

Brigitte S Naughton, Swapnil C Devarkar, Sunanda Mallik, Stacey Oxendine, Sanjana Junnarkar, Yuan Ren, Vanessa Todorow, Julien Berro, Janine Kirstein, Yong Xiong, Christian Schlieker

PIEZO-dependent mechano-sensing of the niche is essential for intestinal stem cell fate decision and maintenance

Meryem B. Baghdadi, Ronja M. Houtekamer, Louisiane Perrin, Abilasha Rao-Bhatia, Myles Whelen, Linda Decker, Martin Bergert, Carlos Pérez-Gonzàlez, Réda Bouras, Giacomo Gropplero, Adrian KH Loe, Amin Afkhami-Poostchi, Xin Chen, Xi Huang, Stephanie Descroix, Jeffrey L. Wrana, Alba Diz-Muñoz, Martijn Gloerich, Arshad Ayyaz, Danijela Matic Vignjevic, Tae-Hee Kim

Mouse nephron formation is impaired by moderate-dose arsenical exposure

Carlos Agustin Isidro Alonso, Jenna Haverfield, Gabriela Regalado, Sihem Sellami, Natascha Gagnon, Ajay Rajaram, Pierre Olivier Fiset, Aimee K Ryan, Koren K Mann, Indra R Gupta

Control of alveolar bone development, homeostasis, and socket healing by salt inducible kinases

Nicha Tokavanich, Byron Chan, Katelyn Strauss, Christian D. Castro Andrade, Yuki Arai, Mizuki Nagata, Marc Foretz, Daniel J. Brooks, Noriaki Ono, Wanida Ono, Marc N. Wein

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells

Kaitlin P. McCreery, Aki Stubb, Rebecca Stephens, Nadezda A. Fursova, Andrew Cook, Kai Kruse, Anja Michelbach, Leah C. Biggs, Adib Keikhosravi, Sonja Nykänen, Christel Hydén-Granskog, Jizhong Zou, Jan-Wilm Lackmann, Carien M. Niessen, Sanna Vuoristo, Yekaterina A. Miroshnikova, Sara A. Wickström

Robinow Syndrome DVL1 mutations disrupt morphogenesis and appendage formation in a Drosophila disease model

Gamze Akarsu, Katja R MacCharles, Kenneth Kin Lam Wong, Joy Richman, Esther M. Verheyen

Substrate stiffness regulates neuronal maturation via Piezo1-mediated TTR activity

Eva Kreysing, Helene Gautier, Robert J Humphrey, Katrin A Mooslehner, Leila A Muresan, Daniel Haarhoff, Sudipta Mukherjee, Xiaohui X Zhao, Alex K Winkel, Andrea Dimitracopoulos, Eva K Pillai, Ragnhildur Thora Karadottir, Kristian Franze

Calreticulin is required for cuticle deposition and trabeculae formation inside butterfly wing scale cells

Ru Hong, Cedric Finet, Antonia Monteiro

Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud

Min Shi, Brittney Crouse, Nambirajan Sundaram, Naomi Pode Shakked, Lioba Ester, Weitao Zhang, Vinothini Janakiram, Raphael Kopan, Michael A. Helmrath, Joseph V. Bonventre, Kyle W. McCracken

Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation

Helena A Crellin, Chengxi Zhu, Guillermo Serrano-Nájera, Amelia Race, Kevin O’Holleran, Martin O Lenz, Clare E Buckley

Centralspindlin promotes C. elegans anchor cell specification, vulva induction and morphogenesis

Tatsuya Kato, Olga Skorobogata, Christian Rocheleau

Microtubules coordinate mitochondria transport with myofibril morphogenesis during muscle development

Jerome Avellaneda, Duarte Candeias, Ana da Rosa Soares, Edgar R. Gomes, Nuno Miguel Luis, Frank Schnorrer

From Avellaneda et al. This image is made available under a CC-BY-ND 4.0 International license.

Mechanical coupling of compartments drives polarity and patterning of mouse auditory epithelium

Anubhav Prakash, Sukanya Raman, Raman Kaushik, Anton S Iyer, Raj K. Ladher

ARHGEF3 Regulates Hair Follicle Morphogenesis

Krithika Kalyanakrishnan, Amy Beaudin, Alexandra Jetté, Sarah Ghezelbash, Diana Ioana Hotea, Jie Chen, Philippe Lefrançois, Mélanie Laurin

The pericardium forms as a distinct structure during heart formation

Hannah R. Moran, Obed O. Nyarko, Rebecca O’Rourke, Ryenne-Christine K. Ching, Fréderike W. Riemslagh, Brisa Peña, Alexa Burger, Carmen C. Sucharov, Christian Mosimann

Mechanical regulation of cuboidal-to-squamous epithelial transition in the Drosophila developing wing

Stefan Harmansa, Thomas Lecuit

| Genes & genomes

Dynamic allelic expression in mouse mammary gland across the adult developmental cycle

Geula Hanin, Kevin R Costello, Hugo Tavares, Shrina Patel, Anne C Ferguson-Smith

The Hox Gene, abdominal A controls timely mitotic entry of neural stem cell and their growth during CNS development in Drosophila

Papri Das, Smrithi Murthy, Eshan Abbas, Kristin White, Richa Arya

Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development

Alexandra de la Porte, Julia Schröder, Moritz Thomas, Johanna Geuder, Michael Sterr, Xavier Pastor, Leslie E. Sanderson, Tahsin Stefan Barakat, Wolfgang Enard, Carsten Marr, Christian Schröter, Micha Drukker

The Transcription Factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development

Gal Finer, Mohammad D. Khan, Yalu Zhou, Gaurav Gadhvi, George S. Yacu, Joo-Seop Park, R. Ariel Gomez, Maria Luisa Sequeira-Lopez, Susan E. Quaggin, Deborah R. Winter

The Pax transcription factor EGL-38 links EGFR signaling to assembly of a cell-type specific apical extracellular matrix in the Caenorhabditis elegans vulva

Helen F. Schmidt, Chelsea B. Darwin, Meera V. Sundaram

The Drosophila myogenic inhibitor Him gene is essential for adult muscle function and muscle stem cell maintenance

Robert Mitchell-Gee, Robert Hoff, Kumar Vishal, Daniel Hancock, Sam McKitrick, Cristina Newnes-Querejeta, TyAnna L. Lovato, Richard M. Cripps, Michael V. Taylor

Pcbp1 constrains Oct4 expression in the context of pluripotency

E. I. Bakhmet, A. S. Zinovyeva, A. A. Kuzmin, D. V. Smirnova, M. N. Gordeev, E. E. Petrenko, N. D. Aksenov, A. N. Tomilin

Deciphering the Cell-Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish

Xiumei Lin, Xue Wang, Chang Liu, Chuanyu Liu, Tao Zeng, Ziqi Yuan, Meidi Hu, Rong Xiang, Kaichen Zhao, Jie Zhou, Shichen Yang, Yang Wang, Kaifeng Meng, Hui Wang, Guangli He, Rui Zhao, Jiaheng Liu, Yunqi Huang, Jingfang Pan, Jialu Wang, Junyi Chen, Fei Guo, Yuliang Dong, Xun Xu, Daji Luo, Ying Gu, Longqi Liu, Zhiqiang Dong, Liang Chen

Epigenetic priming of embryonic enhancer elements coordinates developmental gene networks

Christopher D Todd, Jannat Ijaz, Fereshteh Torabi, Oleksandr Dovgusha, Stephen Bevan, Olivia Cracknell, Tim Lohoff, Stephen Clark, Ricard Argelaguet, Juliette Pearce, Ioannis Kafetzopoulos, Alice Santambrogio, Jennifer Nichols, Ferdinand von Meyenn, Ufuk Guenesdogan, Stefan Schoenfelder, Wolf Reik

From Todd et al. This image is made available under a CC-BY 4.0 International license.

Cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex

Xiangbin Ruan, Kaining Hu, Yalan Yang, Runwei Yang, Elizabeth Tseng, Bowei Kang, Aileen Kauffman, Rong Zhong, Xiaochang Zhang

The chromatin remodeler DEK promotes proliferation of mammary epithelium and is associated with H3K27me3 epigenetic modifications

Megan Johnstone, Ashley Leck, Taylor Lange, Katherine Wilcher, Miranda S. Shephard, Aditi Paranjpe, Sophia Schutte, Susanne Wells, Ferdinand Kappes, Nathan Salomonis, Lisa M. Privette Vinnedge

Autism and Intellectual Disability-Associated MYT1L Mutation Alters Human Cortical Interneuron Differentiation, Maturation, and Physiology

Ramachandran Prakasam, Julianna Determan, Mishka Narasimhan, Renata Shen, Maamoon Saleh, Gareth Chapman, Komal Kaushik, Paul Gontarz, Kesavan Meganathan, Bilal Hakim, Bo Zhang, James E Huettner, Kristen L Kroll

Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis

William Toubiana, Zoe Dumas, Marie Delattre, Tanja Schwander

Robust Binding Capability and Loss of Telomere-Binding Proteins Underlying the Evolution of Telomeric Repeat Motifs

Hobum Song, Seonhong Kim, Daisy S. Lim, Hee-Jung Choi, Junho Lee

Optimized CRISPR inhibition and activation opens key avenues for systematic biological exploration in zebrafish

Nelson B. Barrientos, Elyse A. Shoppell, Rachel J. Boyd, Valeria C. Culotta, Andrew S. McCallion

Sex-, development-, and nutrition-dependent expression of a major age-at-maturity gene in Atlantic salmon

Eirik Ryvoll Åsheim, Paul Vincent Debes, Andrew House, Petra Liljeström, Annukka Ruokolainen, Morgane Frapin, Iikki Donner, Ehsan Pashay Ahi, Jaakko Erkinaro, Jukka-Pekka Verta, Craig R Primmer

De novo assembly of the selfish t supergene reveals a deleterious evolutionary trajectory

Jan-Niklas Runge, Kristian Ullrich, Anna K. Lindholm

The Drosophila maternal-effect gene abnormal oocyte (ao) does not repress histone gene expression

Risa Takenaka, Sierra M. Simmerman, Casey A. Schmidt, Eric H. Albanese, Leila E. Rieder, Harmit S. Malik

The Primate Major Histocompatibility Complex: An Illustrative Example of Gene Family Evolution

Alyssa Lyn Fortier, Jonathan K. Pritchard

Evolutionary genomics predicts adaptive genetic and plastic gene expression responses to climate change in a key alpine forest tree species

Zhiqin Long, Yupeng Sang, Jiajun Feng, Xinxin Zhang, Tingting Shi, Lushui Zhang, Kangshan Mao, Loren H. Rieseberg, Jianquan Liu, Jing Wang

Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis

Zoé Dumas, William Toubiana, Marie Delattre, Tanja Schwander

From Dumas et al. This image is made available under a CC-BY-NC-ND 4.0 International license.

Expansion of Drosophila haemocytes using a conditional GeneSwitch driver affects larval haemocyte function, but does not modulate adult lifespan or survival from infection

Dan J Hayman, Lola M Morrin, Sudipta Halder, Eleanor J Phillips, Mirre J P Simons, Iwan R Evans

Developmental transcriptomics in Pristionchus reveals the logic of a plasticity gene regulatory network

Shelley Reich, Tobias Loschko, Julie Jung, Samantha Nestel, Ralf J. Sommer, Michael S. Werner

The L1CAM SAX-7 is an antagonistic modulator of Erk Signaling

Melinda Moseley-Alldredge, Caroline Aragón, Marcus Vargus, Divya Alley, Nirali Somia, Lihsia Chen

NR2F2 regulation of interstitial to fetal Leydig cell differentiation in the testis: insights into differences of sex development

Martín Andrés Estermann, Sara Grimm, Abigail Kitakule, Karina Rodriguez, Paula Brown, Kathryn McClelland, Ciro Amato, Humphrey Hung-Chang Yao

Enhancer adoption by an LTR retrotransposon generates viral-like particles causing developmental limb phenotypes

Juliane Glaser, Giulia Cova, Beatrix Fauler, Cesar A. Prada-Medina, Virginie Stanislas, Mai H.Q. Phan, Robert Schöpflin, Yasmin Aktas, Martin Franke, Guillaume Andrey, Christina Paliou, Verena Laupert, Wing-Lee Chan, Lars Wittler, Thorsten Mielke, Stefan Mundlos

Gene regulatory dynamics during craniofacial development in a carnivorous marsupial

Laura E. Cook, Charles Y. Feigin, John Hills, Davide M. Vespasiani, Andrew J. Pask, Irene Gallego Romero

Effects of alcohol on the transcriptome, methylome, and metabolome of in vitro gastrulating human embryonic cells

Essi Wallen, Karita Ramo, Jussi Vehvilainen, Joonas Sokka, Marko Lehtonen, Timo Otonkoski, Ras Trokovic, Pauliina Auvinen, Olli Karkkainen, Nina Kaminen-Ahola

Live imaging human embryos reveals mitotic errors and lineage specification prior to implantation

Ahmed Abdelbaki, Afshan McCarthy, Anita Karsa, Leila Muresan, Kay Elder, Athanasios Papathanasiou, Phil Snell, Leila Christie, Martin Wilding, Benjamin J. Steventon, Kathy K. Niakan

Genomic mosaicism reveals developmental organization of trunk neural crest-derived ganglia

Keng Ioi Vong, Yanina D. Alvarez, Geoffroy Noel, Scott T. Barton, Changuk Chung, Robyn Howarth, Naomi Meave, Qingquan Zhang, Fiza Jiwani, Chelsea Barrows, Arzoo Patel, Jiang Xiong Wang, Neil Chi, Stephen F. Kingsmore, Melanie D. White, Xiaoxu Yang, Joseph G. Gleeson

Dynamic transcriptional and epigenetic changes define postnatal tendon growth

Heather L. Dingwall, Mor Grinstein, Terence D. Capellini, Jenna L. Galloway

Elavl1 is dispensable for appendicular skeletal development

Rohini Parsha, Satya K. Kota

Fast-twitch myofibrils grow in proportion to Mylpf dosage in the zebrafish embryo

Tayo E Adekeye, Emily M Teets, Emily A Tomak, Sadie L Waterman, Kailee A Sprague, Angelina White, Maddison L Coffin, Sabrina M Varga, Teresa E Easterbrooks, Sarah J Shepherd, Jared D Austin, Dmitrii Krivorotko, Troy E Hupper, Joshua B Kelley, Sharon L Amacher, Jared C Talbot

LINE1 promotes nuclear compartmentalization to repress the 8-cell state in embryonic stem cells

Juan Zhang, Lamisa Ataei, Liang Wu, Kirti Mittal, Linh Huynh, Shahil Sarajideen, Abdul Mazid, David P. Cook, Daniel Trcka, Kevin Tse, Jeffrey L. Wrana, Michael M. Hoffman, Miguel A. Esteban, Miguel Ramalho-Santos

Distinct Roles for SETα and SETβ in Early Cell Fate Decisions

Patrick Siang Lin Lim, Eran Meshorer

Highly conserved sequence-specific double-stranded DNA binding networks contributing to divergent genomic evolution of human and chimpanzee brain development

Gennadi Glinsky

| Stem cells, regeneration & disease modelling

Ciliary marginal zone of the developing human retina maintains retinal progenitor cells until late gestational stages

Kiara C. Eldred, Sierra J. Edgerton, Isabel Ortuño-Lizarán, Juliette Wohlschlegel, Stephanie M. Sherman, Sidnee Petter, Gracious Wyatt-Draher, Dawn Hoffer, Ian Glass, Anna La Torre, Thomas A. Reh

The miR-290 and miR-302 clusters are essential for reprogramming of fibroblasts to induced pluripotent stem cells

Julia Ye, Ryan M. Boileau, Ronald J. Parchem, Robert L. Judson-Torres, Robert Blelloch

An RNA binding regulatory cascade controls the switch from proliferation to differentiation in the Drosophila male germ line stem cell lineage

Devon E. Harris, Jongmin J. Kim, Sarah R. Stern, Hannah M. Vicars, Neuza R. Matias, Lorenzo Gallicchio, Catherine C. Baker, Margaret T. Fuller

Secretome analysis by proximal labeling in Golgi apparatus for identifying fat body derived humoral factors in Drosophila disc regeneration

Yutaka Yoshida, Soshiro Kashio, Masayuki Miura

The Initiator Caspase Dronc Drives Compensatory Proliferation of Apoptosis-Resistant Cells During Epithelial Tissue Regeneration After Ionizing Radiation

Tslil Braun, Naama Afgin, Lena Sapozhnikov, Ehud Sivan, Andreas Bergmann, Luis Alberto Baena-Lopez, Keren Yacobi-Sharon, Eli Arama

Organoid Modeling and Single-Cell Profiling Uncover the Migration Mechanism of Smooth Muscle Cells in Moyamoya Disease

Shihao He, Junze Zhang, Xilong Wang, Zhen Qi, Zhenyu Zhou, Yanru Wang, Shaoqi Xu, Dandan Li, Xun Ye, Ziqi Liu, Xiaokuan Hao, Yuanli Zhao, Rong Wang

Culture Conditions Differentially Regulate the Inflammatory Niche and Cellular Phenotype of Tracheo-Bronchial Basal Stem Cells

Shubha Murthy, Denise A. Seabold, Lalit K. Gautam, Adrian M. Caceres, Rosemary Sease, Ben A. Calvert, Shana Busch, Aaron Neely, Crystal N. Marconett, Amy L. Ryan

Simultaneous generation of osteoblasts and adipocytes by a bivalent differentiation medium from bone marrow stromal/stem cells (BMSCs)

Dawei Qiu, Dong Liu, Jia Chen, Jingwen Huang, Yong Yang, Wanyi Wei, Ziwei Luo

Proliferation and differentiation of intestinal stem cells depends on the zinc finger transcription factor BCL11/Chronophage

Siamak Redhai, Nick Hirschmüller, Tianyu Wang, Shivohum Bahuguna, Svenja Leible, Stefan Peidli, Erica Valentani, Sviatoslav Kharuk, Michaela Holzem, Lea Bräckow, Fillip Port, David Ibberson, Wolfgang Huber, Michael Boutros

Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty

Daniel Sheridan, Probir Chakravarty, Gil Golan, Yolanda Shiakola, Christophe Galichet, Patrice Mollard, Philippa Melamed, Robin Lovell-Badge, Karine Rizzoti

Hypoxia and loss of GCM1 expression prevents differentiation and contact inhibition in human trophoblast stem cells

Jessica K. Cinkornpumin, Sin Young Kwon, Anna-Maria Prandstetter, Theresa Maxian, Jacinthe Sirois, James Goldberg, Joy Zhang, Deepak Saini, Purbasa Dasgupta, Mariyan J. Jeyarajah, Stephen Renaud, Soumen Paul, Sandra Haider, William A Pastor

MIXL1 Activation in Endoderm Differentiation of Human Induced Pluripotent Stem Cells

Pierre Osteil, Sarah Withey, Nicole Santucci, Nader Aryamanesh, Chi Nam Ignatius Pang, Nazmus Salehin, Jane Sun, Annie Qin, Jiayi Su, Hilary Knowles, Zhaoxiang Cai, Xiucheng Bella Li, Ernst J Wolvetang, Patrick P.L. Tam

Modulating DNA Polα Enhances Cell Reprogramming Across Species

Rajesh Ranjan, Binbin Ma, Ryan J. Gleason, Yijun Liao, Yingshan Bi, Brendon E. M. Davis, Guanghui Yang, Maggie Clark, Vikrant Mahajan, Madison Condon, Nichole A. Broderick, Xin Chen

Single Cell Profiling in the Sox10Dom/+ Hirschsprung Mouse Implicates Hoxa6 in Enteric Neuron Lineage Allocation

Justin A. Avila, Joseph T. Benthal, Jenny C. Schafer, E. Michelle Southard-Smith

RFX3 is essential for the development and maturation of human pancreatic islets derived from pluripotent stem cells

Bushra Memon, Noura Aldous, Ahmed K. Elsayed, Sadaf Ijaz, Sikander Hayat, Essam M. Abdelalim

Identification of neurodevelopmental organization of the cell populations of juvenile Huntington’s disease using dorso-ventral HD organoids and HD mouse embryos

Karolina Świtońska-Kurkowska, Jakub Kubiś, Joanna Delimata-Raczek, Bart Krist, Magda Surdyka, Żaneta Kalinowska-Pośka, Piotr Piasecki, Luiza Handschuh, Jan Podkowiński, Magdalena Rakoczy, Anna Samelak-Czajka, Michael Hayden, Nicholas S Caron, Maciej Figiel

From Świtońska-Kurkowska et al. This image is made available under a CC-BY 4.0 International license.

Reducing oxidative stress improves ex vivo polymer-based human haematopoietic stem and progenitor cell culture and gene editing

Yavor Bozhilov, Elizabeth Brown, Ian Hsu, Indranil Singh, Alejo Rodriguez-Fraticelli, Anindita Roy, Satoshi Yamazaki, Adam C. Wilkinson

MEK1/2 kinases cooperate with c-Myc:MAX to prevent polycomb repression of TERT in human pluripotent stem cells

Spandana Kotian, Lindsay F. Rizzardi, Josh L. Stern

Human iPSC-derived brain pericytes exhibit differences in inflammatory activation compared to primary human brain pericytes

Samuel JC McCullough, Eliene Albers, Akshata Anchan, Jane Yu, Simon J O’Carroll, Bronwen Connor, E Scott Graham

Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors

Kutay Karatepe, Bruna Mafra de Faria, Jian Zhang, Xinyue Chen, Hugo Pinto, Dmitry Fyodorov, Esen Sefik, Michael Willcockson, Richard Flavell, Arthur Skoultchi, Shangqin Guo

Early lineage segregation of primary myotubes from secondary myotubes and adult muscle stem cells

Gauthier Toulouse, William Jarassier, Valérie Morin, Fabien Le Grand, Christophe Marcelle

Inflammation perturbs hematopoiesis by remodeling specific compartments of the bone marrow niche

James W. Swann, Ruiyuan Zhang, Evgenia V. Verovskaya, Fernando J. Calero-Nieto, Xiaonan Wang, Melissa A. Proven, Peter T. Shyu, X. Edward Guo, Berthold Göttgens, Emmanuelle Passegué

Metabolic reprogramming regulates histone lactylation during zebrafish caudal fin regeneration

Jorge Borbinha, Raquel Lourenco, Ana Sofia Brandao, Ana Carvalho, Rune Matthiesen, Antonio Jacinto

Differential responses and recovery dynamics of HSPC populations following Plasmodium chabaudi infection.

Federica Bruno, Christiana Georgiou, Deirdre Cunningham, Samantha Atkinson, Lucy Bett, Marine Secchi, Flora Birch, Sara Gonzalez Anton, jean langhorne, Cristina Lo Lo Celso

Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development

Silvia Vicenzi, Fangyuan Gao, Parker Côté, Joshua D. Hartman, Lara C. Avsharian, Ashni A. Vora, R. Grant Rowe, Hojun Li, Dorota Skowronska-Krawczyk, Leslie A. Crews

Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells

Rachel Wellington, Xiaoyi Cheng, Clyde A. Campbell, Cole Trapnell, Raquel Espin-Palazon, Brandon Hadland, Sergei Doulatov

Bnip3lb-driven mitophagy sustains expansion of the embryonic hematopoietic stem cell pool

Eleanor Meader, Morgan T. Walcheck, Mindy R. Leder, Ran Jing, Paul J. Wrighton, Wade W. Sugden, Mohamad A. Najia, Isaac M. Oderberg, Vivian M. Taylor, Zachary C. LeBlanc, Eleanor D. Quenzer, Sung-Eun Lim, George Q. Daley, Wolfram Goessling, Trista E. North

Apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2/APE2) is required for efficient expression of TERT in human embryonic stem cells

Josh L. Stern, Lindsay F. Rizzardi, Natalie R. Gassman

Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye

Alicia Hurtado, Víctor López-Soriano, Miguel Lao, M. Ángeles Celis-Barroso, Pilar Lazúen, Alejandro Chacón de Castro, Yolanda Ramírez-Casas, Miguel Alaminos, J. Martin Collinson, Miguel Burgos, Rafael Jiménez, F. David Carmona, Francisco J. Barrionuevo

Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila

André B. Medina, Jessica Perochon, Cai Johnson, Sofia Polcowñuk, Yuanliangzi Tian, Yachuan Yu, Julia B. Cordero

From Medina et al. This image is made available under a CC-BY 4.0 International license.

| Plant development

Raffinose induces autophagy to promote plant growth

Sahar Magen, Sahar Daniel, Shahar Weiss, David J. Factor, Sergey Mursalimov, Yoram Soroka, Simon Michaeli, Tamar Avin-Wittenberg

ETTIN-mediated auxin signalling is an angiosperm-specific neofunctionalization for carpel development

Aaron Chun Hou Ang, Sumanth Mutte, Dolf Weijers, Lars Østergaard

Evolutionary conserved RLF, a plant cytochrome b5-like heme-binding protein, is essential for organ development in Marchantia polymorpha

Kentaro P. Iwata, Takayuki Shimizu, Yuuki Sakai, Tomoyuki Furuya, Hinatamaru Fukumura, Yuki Kondo, Tatsuru Masuda, Kimitsune Ishizaki, Hidehiro Fukaki

Deciphering transcriptional programming during lupin (Lupinus angustifolius) seed development using RNA-seq

Virginia Wainaina, Tina Rathjen, Trijntje Hughes, Annelie Marquardt, Natalie Fletcher, Hayley Casarotto, Meredith McNeil, Kerensa McElroy, Ling-Ling Gao

CUP-SHAPED COTYLEDON2 activates MIR319C transcription and promotes cell proliferation in Arabidopsis leaf primordia

Naveen Shankar, Abhishek Gupta, Somsree Roy, Vishwadeep Mane, Olivier Hamant, Utpal Nath

Recruitment of SH3P2–DRP1A by HYCCIN2 Drives Membrane Tubulation in Arabidopsis Embryonic Cell Plate Formation

Ya-Wen Hsu, Chine-Ta Juan, Cian-Ling Guo, Huei-Jing Wang, Guang-Yuh Jauh

The fate of pollen in two morphologically contrasting buzz-pollinated Solanum flowers

Christian Ary Vasquez-Castro, Elodie Morel, Bernardo Garcia-Simpson, Mario Vallejo-Marin

Floral Reversion based micropropagation of Day-Neutral Cannabis sativa L

Darya Sadat Tabatabaei, Rambod Abiri, A.M.P. Jones

Genomic imprinting in an early-diverging angiosperm reveals ancient mechanisms for seed initiation in flowering plants

Ana M. Florez-Rueda, Mathias Scharmann, Leonardo P. de Souza, Alisdair R. Fernie, Julien B. Bachelier, Duarte D. Figueiredo

Stable and dynamic gene expression patterns over diurnal and developmental timescales in Arabidopsis thaliana

Ethan J Redmond, James Ronald, Seth J Davis, Daphne Ezer

Integrated Transcriptome and Metabolome Analyses Reveal the Mechanism Regulating Bulbil Initiation and Development in Cystopteris chinensis

An Yu, Xiaohong Chen, Wenkai Xi, Xia Zhao, Yazhu Wang, Zhihong Gong, Xiaofeng Zhou

A genome-wide association screen for genes affecting leaf trichome development and epidermal metal accumulation in Arabidopsis

Radek Bezvoda, Yazmín Mónica Landeo-Ríos, Zdeňka Kubátová, Eva Kollárová, Ivan Kulich, Wolfgang Busch, Viktor Žárský, Fatima Cvrčková

From Bezvoda et al. This image is made available under a CC-BY 4.0 International license.

Integration of light quality signals regulates ABA abundance and stomatal movements during seedling establishment

Mathilda Gustavsson, Lionel Hill, Keara A. Franklin, Ashley J. Pridgeon

Non-CG DNA methylation modulates hypocotyl elongation during thermormorphogenesis

Maián Garro, Eleonora Greco, Gustavo J. Vannay, Aleksandra Leonova, Leonardo Bruno, Matías Capella

| Evo-devo

Climatic-environmental influences on hominin brain size over the last 5 million years

Samuel L. Nicholson, Thomas A. Püschel, Joanna Baker, Chris Venditti

Toxoplasma gondii infection misdirects placental trophoblast lineage specification

Leah F. Cabo, Liheng Yang, Mingze Gao, Rafaela J. da Silva, NyJaee N. Washington, Sarah M. Reilly, Christina J. Megli, Carolyn B. Coyne, Jon P. Boyle

Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations

Sulov Saha, Clemence Debacq, Christophe Audouard, Thomas Jungas, Pierrick Dupre, Mohamad Ali Fawal, Clement Chapat, Henri-Alexandre Michaud, Laurent Le Cam, Matthieu Lacroix, David Ohayon, Alice Davy

Direct measurement of the mutation rate and its evolutionary consequences in a critically endangered mollusk

T. Brock Wooldridge, Sarah Ford, Holland Conwell, John Hyde, Kelley Harris, Beth Shapiro

Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease

Yao-Chung Chen, Arnaud Maupas, Katja Nowick

A glyphosate-based herbicide selects for genetic changes while retaining within-species diversity in a freshwater bacterioplankton community

Emma Derrick, Naíla Barbosa da Costa, Rowan D. H. Barrett, B. Jesse Shapiro

Shared selection and genetic architecture drive strikingly repeatable evolution in long-term experimental hybrid populations

Gregory L. Owens, Celine Caseys, Nora Mitchell, Sariel Hübner, Kenneth D. Whitney, Loren H. Rieseberg

Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling

J. Luis Leal, Eva Hodková, Anja Billhardt, D. Magnus Eklund, Gustaf Granath, Pilar Herrera Egoavil, Jun Chen, Pascal Milesi, Jarkko Salojärvi, Martin Lascoux

Convergent evolution associated with the loss of developmental diapause may promote extended lifespan in bees

Priscila K. F. Santos, Karen M. Kapheim

How environment and genetic architecture of unreduced gametes shape the establishment of autopolyploids

Yu Cheng, Filip Kolář, Roswitha Schmickl, Josselin Clo

Cell differentiation controls iron assimilation in a choanoflagellate

Fredrick Leon, Jesus M. Espinoza-Esparza, Vicki Deng, Maxwell C. Coyle, Sarah Espinoza, David S. Booth

Morphometric evaluation of the anterior cranial fossa during the prenatal stage in humans and its clinical implications

Derkowski Wojciech, Kędzia Alicja, Dudek Krzysztof, Glonek Michał

Ventral-to-dorsal electrocyte development in electric organs of electric eel (Electrophorus)

Sinlapachai Senarat, Ayako Matsumoto, Shintaro Sakaki, Daichi Tsuzuki, Kazuko Uchida, Makoto Kuwahara, Eiichi Hondo, Atsuo Iida

An evolutionarily conserved Hox-Gbx segmentation code in the rice coral Montipora capitata

Shuonan He, Emma Rangel-Huerta, Eric Hill, Lacey Ellington, Shiyuan Chen, Sofia Robb, Eva Majerov, Crawford Drury, Matthew Gibson

Homeodomain protein codes specify neuronal diversity in the first ganglion of the Drosophila visual system

Chundi Xu, Peter Newstein, Rishi Sastry, Chris Doe

The multi-level effect of chlorpyrifos during clownfish metamorphosis

Mathieu Reynaud, Stefano Vianello, Shu-Hua Lee, Pauline Salis, Kai Wu, Bruno Frederich, David Lecchini, Laurence Besseau, Natacha Roux, Vincent Laudet

Evolution of the neural sex-determination system in insects: The doublesex homolog in crickets functions as an X-linked masculinizing factor to regulate morphological but not behavioral sexual dimorphism

Takayuki Watanabe

The role of vibration amplitude in the escape hatching response of red-eyed treefrog embryos

Julie Jung, Michael S. Caldwell, J. Gregory McDaniel, Karen M. Warkentin

Cell Biology

The spatiotemporal distribution of LIN-5/NuMA regulates spindle orientation and tissue organization in the C. elegans germ line

Réda M. Zellag, Vincent Poupart, Takefumi Negishi, Jean-Claude Labbé, Abigail R. Gerhold

From Zellag et al. This image is made available under a CC-BY-NC 4.0 International license.

Distinct Non-occluding Functions of Septate Junction Components in Signaling Pathway Regulation and Cell Polarity During Epithelial Development

V. Holtwick, A. Schubert, K. Rust

Non-random segregation of mitochondria during asymmetric cell division contributes to cell fate divergence in daughter cells

Ioannis Segos, Jens Van Eeckhoven, Simon Berger, Nikhil Mishra, Eric J. Lambie, Barbara Conradt

Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells

Seiichi Koike, Masashi Tachikawa, Motosuke Tsutsumi, Takuya Okada, Tomomi Nemoto, Kazuko Keino-Masu, Masayuki Masu

Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts

Gabriel Guilloux, Maiko Kitaoka, Karel Mocaer, Claire Heichette, Laurence Duchesne, Rebecca Heald, Thierry Pécot, Romain Gibeaux

The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice.

Atsuko Kageyama, Narumi Ogonuki, Takuya Wakai, Takafumi Namiki, Yui Kawata, Manabu Ozawa, Yasuhiro Yamada, Toshiyuki Fukada, Atsuo Ogura, Rafael A. Fissore, Naomi Kashiwazaki, Junya Ito

gilgamesh, Drosophila casein kinase 1g, is required for myosin-dependent junction strengthening and epithelial folding

Lingkun Gu, Reina Benefiel, Jasneet Brar, Mo Weng

Decidual natural killer cells promote extravillous trophoblast developmental pathways: evidence from trophoblast organoid co-cultures

Morgan Zych, Natalie Lo, Kate A Patton, Kewei Wang, Brian J Cox

Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programs and repeats in pluripotent cells

Jingchao Zhang, Greg Donahue, Michael B. Gilbert, Tomer Lapidot, Dario Nicetto, Kenneth S. Zaret

Co-transcriptional RNA processing boosts zygotic gene activation

Jingzhao Xu, XiaoJing Li, Xiaowen Hao, Xinyun Hu, Shaoqian Ma, Yantao Hong, Jing Zhang, Dingfei Yan, Haiteng Deng, Jie Na, Xiong Ji, Zai Chang, Xiaohua Shen

“Mitotic” kinesin-5 is a dynamic brake for axonal growth

Wen Lu, Brad S. Lee, Helen Xue Ying Deng, Margot Lakonishok, Enrique Martin-Blanco, Vladimir I. Gelfand

Restorative macrophage-derived RNAseT2 stimulates muscle stem cell fusion via an SLK/N-WASP/actin bundling dependent axis

Michèle Weiss-Gayet, Gaëtan Juban, Emmeran Le Moal, Antonio Moretta, Camilla Farnetani, Christelle Gobet, Jules Guillemaud, Marie-Catherine Le Bihan, Oded Shoseyov, Annie Adrait, Katharina Ternka, Odile Boespflug-Tanguy, Matthias Kettwig, Yohann Couté, Rémi Mounier, Francesco Acquati, Robert D Knight, Bénédicte Chazaud

Key roles of the zona pellucida and perivitelline space in promoting gamete fusion and fast block to polyspermy inferred from the choreography of spermatozoa in mice oocytes

Yaělle Dubois, Sophie Favier, Nathan Martin-Fornier, Mohyeddine Omrane, David Stroebel, Eric Perez, Sandrine Barbaux, Ahmed Ziyyat, Nicolas Rodriguez, Christine Gourier

Pdgfab/Pdgfra-mediated chemoattraction guides the migration of sclerotome-derived fibroblast precursors in zebrafish

Emilio E. Méndez-Olivos, Katrinka M. Kocha, Shan Liao, Peng Huang

Localized translation of erm-1 contributes to ERM-1 function in the C. elegans embryo

Elise van der Salm, Esther Koelewijn, Erica van der Maas, Max Eeken, Suzan Ruijtenberg

Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution

Julie Uveira, Antoine Donati, Marvin Léria, Marion Lechable, François Lahaye, Christine Vesque, Evelyn Houliston, Tsuyoshi Momose

From Uveira et al. This image is made available under a CC-BY-ND 4.0 International license.

Modelling

Cell geometry, microtubule anchoring and anisotropic dynamic instability: challenges and solutions to transverse cortical array organization

Tim Y.Y. Tian, Geoffrey O. Wasteneys, Colin B. Macdonald, Eric N. Cytrynbaum

From Genes to Patterns: A Framework for Modeling the Emergence of Embryonic Development from Transcriptional Regulation

Jimena Garcia-Guillen, Ezzat El-Sherif

Single-cell multi-omics, spatial transcriptomics and systematic perturbation decode circuitry of neural crest fate decisions

Zhiyuan Hu, Sarah Mayes, Weixu Wang, José M. Santos-Pereira, Fabian Theis, Tatjana Sauka-Spengler

Dynamic landscapes and statistical limits on growth during cell fate specification

Gautam Reddy

(Un)buckling mechanics of epithelial monolayers under compression

Chandraniva Guha Ray, Pierre A. Haas

Engineering morphogenesis of cell clusters with differentiable programming

Ramya Deshpande, Francesco Mottes, Ariana-Dalia Vlad, Michael P. Brenner, Alma dal Co

Modelling and calibration of pair-rule protein patterns in Drosophila embryo: From Even-skipped and Fushi-tarazu to Wingless expression networks

Catarina Dias, Rui Dilão

Tools & Resources

Ultrack: pushing the limits of cell tracking across biological scales

Jordão Bragantini, Ilan Theodoro, Xiang Zhao, Teun A.P.M. Huijben, Eduardo Hirata-Miyasaki, Shruthi VijayKumar, Akilandeswari Balasubramanian, Tiger Lao, Richa Agrawal, Sheng Xiao, Jan Lammerding, Shalin Mehta, Alexandre X. Falcão, Adrian Jacobo, Merlin Lange, Loïc A. Royer

From Bragantini et al. This image is made available under a CC-BY-NC 4.0 International license.

Disrupted developmental signaling induces novel transcriptional states

Aleena Patel, Vanessa Gonzalez, Triveni Menon, Stanislav Y. Shvartsman, Rebecca Burdine, Maria Avdeeva

Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets

Joost J.A.P.M. Wijnakker, Gijs J. F. van Son, Daniel Krueger, Willine van de Wetering, Carmen Lopez-Iglesias, Robin Schreurs, Fenna van Rijt, Sangho Lim, Lin Lin, Peter J. Peters, Ralph R. Isberg, Claudia Yanda, Wim de Lau, Hans Clevers

A simple immunohistochemical method for perinatal mammalian ovaries revealed different kinetics of oocyte apoptosis caused by DNA damage and asynapsis

Hiroshi Kogo, Akiko Iizuka-Kogo, Hanako Yamamoto, Maiko Ikezawa, Yukiko Tajika, Toshiyuki Matsuzaki

A community-oriented, data-driven resource to improve protocol design for cardiac modelling from human pluripotent stem cells

Chris Siu Yeung Chow, Sumedha Negi, Shaine Chenxin Bao, Chen Fang, James E. Hudson, Woo Jun Shim, Yuanzhao Cao, Nathan J. Palpant

Large-scale mouse mutagenesis identifies novel genes affecting vertebral development.

Ximena Ibarra-Soria, Elizabeth Webb, John Mulley

Mutant scaling laws reveal that accelerated evolution via gene amplification requires spatially structured population growth

Natalia L. Komarova, Justin Pritchard, Dominik Wodarz

Single-cell proteomics of pre-implantation mouse embryos uncovers distinct asymmetry of certain proteins among early blastomeres

Yuan Yuan, Mo Hu, Yinghui Zheng, Yutong Zhang, Yuxuan Pang, Xiaoliang Sunney Xie

Zebrafish glial-vascular interactions progressively expand over the course of brain development

Lewis G Gall, Courtney M Stains, Moises Freitas-Andrade, Bill Z Jia, Nishi Patel, Sean G Megason, Baptiste Lacoste, Natasha Meyer O’Brown

Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes Towards a Purkinje Fiber Fate

David M. Gonzalez, Rafael Dariolli, Julia Moyett, Stephanie Song, Bhavana Shewale, Jacqueline Bliley, Daniel Clarke, Avi Ma’ayan, Stacey Rentschler, Adam Feinberg, Eric Sobie, Nicole C. Dubois

Leveraging CRISPR activation for rapid assessment of gene editing products in human pluripotent stem cells

Youjun Wu, Aaron Zhong, Alessandro Evangelisti, Mega Sidharta, Lorenz Studer, Ting Zhou

Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity

Takao Yogo, Yuichiro Iwmaoto, Becker Hans Jiro, Takaharu Kimura, Ayano Sugiyama-Finnis, Tomomasa Yokomizo, Toshio Suda, Sadao Ota, Satoshi Yamazaki

Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts

Gabriel Guilloux, Maiko Kitaoka, Karel Mocaer, Claire Heichette, Laurence Duchesne, Rebecca Heald, Thierry Pecot, Romain Gibeaux

A Drosophila holidic diet optimised for growth and development

Sebastian Sorge, Victor Girard, Lena Lampe, Vanessa Tixier, Alexandra Weaver, Theresa Higgins, Alex P. Gould

An explainable map of human gastruloid morphospace reveals gastrulation failure modes and predicts teratogens

Joseph Rufo, Chongxu Qiu, Dasol Han, Naomi Baxter, Gabrielle Daley, Maxwell Z. Wilson

Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs

Çağrı Çevrim, Béryl Laplace-Builhé, Ko Sugawara, Maria Lorenza Rusciano, Nicolas Labert, Jacques Brocard, Alba Almazán, Michalis Averof

From Çevrim et al. This image is made available under a CC-BY 4.0 International license.

Research practice & education

From impact metrics and open science to communicating research: Journalists’ awareness of academic controversies

Alice Fleerackers, Laura L. Moorhead, Juan Pablo Alperin, Michelle Riedlinger, Lauren A. Maggio

When crayfish make news, headlines are correct but still misleading

Zen Faulkes

Updated science-wide author databases of standardized citation indicators including retraction data

John P. A. Ioannidis, Angelo Maria Pezzullo, Antonio Cristiano, Stefania Boccia, Jeroen Baas

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