About: Hannah Long

Biography:

In my research I investigate how gene expression is regulated during development, and how this can go awry in human disease. I have focused on congenital craniofacial abnormalities, and understanding how non-coding genetic mutations can drive these disorders. I did my undergraduate studies at the University of Cambridge in the Natural Sciences, and was awarded her DPhil at the University of Oxford Biochemistry Department in 2014 as a student in the Wellcome Trust Graduate Programme in Chromosome and Developmental Biology. During my PhD, I worked with Professors Rob Klose and Roger Patient to uncover conservation of non-methylated islands across vertebrate species and interrogate DNA sequence features that contribute to DNA methylation status. In my post-doctoral work, as a Sir Henry Wellcome post-doctoral research fellow in the laboratory of Professor Joanna Wysocka at Stanford University, I have investigated mechanisms of developmental gene regulation, with a focus on long-range enhancer function in craniofacial development, evolution and disease.

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