developmental and stem cell biologists
I am a chemist from training, with a strong interest in biology. Our lab develops genetically encoded fluorescent probes and biosensors for quantitative functional imaging with the overarching goal to unravel (G-protein) signalling networks in time and space in cells and tissues. You can follow me on BlueSky: https://bsky.app/profile/joachimgoedhart.bsky.social
Posted by Joachim Goedhart, on 12 December 2018
When we examined the kinetics of Rho GTPase activity in endothelial cells in response to receptor stimulation (Reinhard, 2017), we noticed considerable cell-to-cell heterogeneity. In the original work we published ...Posted by Joachim Goedhart, on 8 October 2018
Calculation and reporting of p-values is common in scientific publications and presentations (Cristea and Ioannidis, 2018). Usually, the p-value is calculated to decide whether two conditions, e.g. control and treatment, ...Posted by Joachim Goedhart, on 26 June 2018
Experiments are rarely performed in isolation. Usually, several conditions are compared in parallel or sequential experiments. This experimental strategy also applies to time-dependent data, e.g. from timelapse imaging. So, naturally, ...Posted by Joachim Goedhart, on 31 May 2018
The visualization of temporal data by line graphs has been documented and popularized by William Playfair in the 18th century (Aigner et al, 2011; Beniger and Robyn, 1978). Today, time-dependent changes ...Posted by Joachim Goedhart, on 18 April 2018
After leaving the bar, what are we to do? I propose to move on to a better bar (and I hope that you will not be disappointed when you find ...
