I am a chemist from training, with a strong interest in biology. Our lab develops genetically encoded fluorescent probes and biosensors for quantitative functional imaging with the overarching goal to unravel (G-protein) signalling networks in time and space in cells and tissues. You can follow me on twitter: @joachimgoedhart or Mastodon: @JoachimGoedhart@mas.to
Posted by Joachim Goedhart, on 26 June 2018
Experiments are rarely performed in isolation. Usually, several conditions are compared in parallel or sequential experiments. This experimental strategy also applies to time-dependent data, e.g. from timelapse imaging. So, naturally, ...Posted by Joachim Goedhart, on 31 May 2018
The visualization of temporal data by line graphs has been documented and popularized by William Playfair in the 18th century (Aigner et al, 2011; Beniger and Robyn, 1978). Today, time-dependent changes ...Posted by Joachim Goedhart, on 18 April 2018
After leaving the bar, what are we to do? I propose to move on to a better bar (and I hope that you will not be disappointed when you find ...Posted by Joachim Goedhart, on 5 April 2018
In a previous blog, I have disgraced parrots by associating them with P-values and discrediting them for their mechanic repetition. Nevertheless, I admire the vivid colours of these multifaceted birds. ...Posted by Joachim Goedhart, on 1 February 2018
Recently, Nature published my correspondence “Dispense with redundant P values”. It highlights my concern that p-values are often calculated because “everybody does it”. This reminded me of the mechanical repetition ...