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developmental and stem cell biologists

Joachim Goedhart

I am a chemist from training, with a strong interest in biology. Our lab develops genetically encoded fluorescent probes and biosensors for quantitative functional imaging with the overarching goal to unravel (G-protein) signalling networks in time and space in cells and tissues. You can follow me on BlueSky: https://bsky.app/profile/joachimgoedhart.bsky.social

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Posts by Joachim Goedhart

Data Visualization with Flying Colors

Posted by , on 29 August 2019

The importance of barrier-free use of colors in images and graphs has been highlighted in letters to editors (Miall, 2007), papers (Geissbuehler and Lasser, 2013, Levine, 2009), editorials (anonymous, 2007), ...

Data manipulation? It's normal(ization)!

Posted by , on 25 June 2019

In a previous blog, I have highlighted several ways to visualize the cell-to-cell heterogeneity from time-lapse imaging data. However, I have ignored that data is often rescaled in a way ...

User-friendly p-values

Posted by , on 13 February 2019

A good statistic is the one that you can understand. Mean values are understandable and everybody knows how to calculate them. Most people also realize how the mean value can ...

Experimenting with non-anonymous peer review

Posted by , on 3 February 2019

Last year, I started to experiment with signing my reports for peer review of manuscripts, inspired by other people on twitter (@kaymtye, @AndrewPlested who in turn were inspired by Leslie ...

Visualizing the heterogeneity of single cell data from time-lapse imaging

Posted by , on 12 December 2018

When we examined the kinetics of Rho GTPase activity in endothelial cells in response to receptor stimulation (Reinhard, 2017), we noticed considerable cell-to-cell heterogeneity. In the original work we published ...

Recent comments by Joachim Goedhart

A follow-up of this post is available: https://thenode.biologists.com/converting-excellent-spreadsheets-part2
by Joachim Goedhart in Converting excellent spreadsheets to tidy data on September 29, 2020