developmental and stem cell biologists
I am a chemist from training, with a strong interest in biology. Our lab develops genetically encoded fluorescent probes and biosensors for quantitative functional imaging with the overarching goal to unravel (G-protein) signalling networks in time and space in cells and tissues. You can follow me on twitter: @joachimgoedhart or Mastodon: @JoachimGoedhart@mas.to
Posted by Joachim Goedhart, on 25 June 2019
In a previous blog, I have highlighted several ways to visualize the cell-to-cell heterogeneity from time-lapse imaging data. However, I have ignored that data is often rescaled in a way ...Posted by Joachim Goedhart, on 13 February 2019
A good statistic is the one that you can understand. Mean values are understandable and everybody knows how to calculate them. Most people also realize how the mean value can ...Posted by Joachim Goedhart, on 3 February 2019
Last year, I started to experiment with signing my reports for peer review of manuscripts, inspired by other people on twitter (@kaymtye, @AndrewPlested who in turn were inspired by Leslie ...Posted by Joachim Goedhart, on 12 December 2018
When we examined the kinetics of Rho GTPase activity in endothelial cells in response to receptor stimulation (Reinhard, 2017), we noticed considerable cell-to-cell heterogeneity. In the original work we published ...Posted by Joachim Goedhart, on 8 October 2018
Calculation and reporting of p-values is common in scientific publications and presentations (Cristea and Ioannidis, 2018). Usually, the p-value is calculated to decide whether two conditions, e.g. control and treatment, ...
