developmental and stem cell biologists
Posted by the Node Interviews, on 5 December 2018
This interview, the 52nd in our series, was the first to be published in Development. We’re aiming for one interview per issue, and will continue to put them up here ...Posted by the Node Interviews, on 24 October 2018
The construction of complex three-dimensional tissue structures during embryogenesis requires precise control of cell and tissue mechanics. The Xenopus embryo provides a powerful tool for interrogating this relationship, as demonstrated ...Posted by the Node Interviews, on 21 September 2018
During early mouse development, a series of signalling interactions breaks the symmetry of the egg cylinder, spatially organising the embryo into territories that define the future axes of the body. ...Posted by the Node Interviews, on 4 September 2018
Axon guidance relies on the reception and integration of molecular cues from the environment by growth cones, and defective pathfinding results in misplaced projection patterns in the mature nervous system. ...Posted by the Node Interviews, on 9 August 2018
The neural crest is a progenitor population with the capacity to contribute to all vertebrate germ layers. The transcription factor and signalling pathway activity underlying this remarkable pluripotency have been well ...