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Flippase recognition target: orientation matters, so why care?

Posted by , on 16 April 2014

FRT sites are used often (at least in Drosophila) for inducing deletions or “flipping out” of markers in transgenic constructs. When there are two FRTs sequences in tandem, after inducing ...
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What's your favourite gene?

Posted by , on 11 April 2014

I recently took part in the ‘I’m a scientist, get me out of here!’ outreach event. As soon as the school children found out I was a developmental geneticist and ...
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Negative findings: tackling the negativity

Posted by , on 18 March 2014

‘Science is often romanticised as a flawless system of knowledge building, where scientists work together to systematically find answers. In reality, this is not always the case. Dissemination of results ...
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In time of revision: of Wingless and morphogens

Posted by , on 27 December 2013

In time of revision: of Wingless and morphogens Alfonso Martinez Arias The recent publication of the important work of C. Alexandre, LA. Baena and JP. Vincent on the molecular requirements ...
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Setting the record straight- an interview with Daniel St Johnston

Posted by , on 3 December 2013

Professor Daniel St Johnston is a prominent developmental biologist and the current director of the Gurdon Institute in Cambridge (UK). The St Johnston lab recently retracted two papers, in what ...
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Conflicts of Interest

Posted by , on 28 October 2013

‘‘None of the scientists would comment on the record, for fear that it would affect their funding or that of their postdocs and graduate students’’ Nature, September 2012 ‘Is science ...
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Evolution of the Human Neocortex: How Unique Are We?

Posted by , on 28 October 2013

“Evolution of the Human Neocortex: How Unique Are We?” was the question asked at the Wiston House in West Sussex from 22-25 September 2013.  Although we were hardly the first to ...
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Neocortex evolution and human uniqueness

Posted by , on 20 October 2013

“So God created mankind in his own image, in the image of God he created them; male and female he created them. God blessed them and said to them, ‘Be fruitful and increase in number; fill the ...
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Cellular Reincarnation

Posted by , on 1 October 2013

Stuck! Here I was trapped in this valley with no way out. And it was crowded here, with all of my fibers I sensed numerous peers condemned to a similar ...
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Where scientists fear to tread

Posted by , on 22 August 2013

I have recently returned from a spate of international conferences that afforded me the opportunity to experience meetings for the first time as an editor, instead of as an active ...
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