CoB Workshop (Day 4): Epigenetic Memory
Posted by dnadave, on 3 July 2012
Reflecting on all the great talks over the course of four days, this meeting has been one of the most enjoyable I’ve been to – I’m sure it was due to equal parts setting and participants. Having a small number of high caliber participants was amenable to lively follow-up discussions either over food, drink, or a friendly game of croquet – again kudos to the organizers and the Company of Biologists. After yet another fantastic lunch we all abruptly disband to the four corners of the world, but, as someone once said, no party can last forever. Back to the lab, fresh with either new or more refined questions to test.
I leave you with some summary points that were articulated on the last day by Sir John Gurdon. Food for thought if you will.
What is the significance of epigenetic memory? To establish and stabilize the somatic cell identity?
However eventually all things will exchange because the marks that maintain this epigenetic memory are either dynamic or can be perturbed.
Hence, what determines the exchange or transition of epigenetic marks? And, what is the basis of resistance.
Until next time. Cheers.
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