Welcome to our monthly trawl for developmental biology (and related) preprints. 

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This month’s trawl includes a veritable farm, with developmental studies of potatoes, beetroot, tomato, maize, wheat, pigs, cows and goats, plus many of the usual suspects. They were hosted on bioRxiv and arXiv. Let us know if we missed anything. Use these links to get to the section you want:

 

Developmental biology

| Patterning & signalling

| Morphogenesis & mechanics

| Genes & genomes

| Stem cells, regeneration & disease modelling

| Plant development

Evo-devo & evo

Cell biology

Modelling

Tools & resources

Research practice & education

Why not…

 

Developmental biology

| Patterning & signalling

Bicc1 and dicer regulate left-right patterning through posttranscriptional control of the Nodal-inhibitor dand5
Markus Maerker, Maike Getwan, Megan E Dowdle, Jose L Pelliccia, Jason C McSheene, Valeria Yartseva, Katsura Minegishi, Philipp Vick, Antonio Giraldez, Hiroshi Hamada, Rebecca D Burdine, Michael D Sheets, Axel Schweickert, Martin Blum

 

Differences in mitochondrial activity trigger cell competition during early mouse development
Ana Lima, Gabriele Lubatti, Jörg Burgstaller, Di Hu, Alistair Green, Aida Di Gregorio, Tamzin Zawadzki, Barbara Pernaute, Elmir Mahammadov, Marian Dore, Juan Miguel Sanchez, Sarah Bowling, Margarida Sancho, Mohammad Karimi, David Carling, Nick Jones, Shankar Srinivas, Antonio Scialdone, Tristan A. Rodriguez

 

 

Cancer-associated HIF-2α impacts trunk neural crest stemness
Sofie Mohlin, Camilla U. Persson, Elina Fredlund, Emanuela Monni, Jessica M. Lindvall, Zaal Kokaia, Emma Hammarlund, Marianne E. Bronner

 

Local retinoic acid directs emergence of the extraocular muscle functional unit
Glenda Comai, Marketa Tesarova, Valerie Dupé, Muriel Rhinn, Pedro Vallecillo Garcia, Fabio da Silva, Betty Feret, Katherine Exelby, Pascal Dollé, Leif Carlsson, Brian Pryce, Francois Spitz, Sigmar Stricker, Tomas Zikmund, Jozef Kaiser, James Briscoe, Andreas Schedl, Norbert B. Ghyselinck, Ronen Schweitzer, Shahragim Tajbakhsh

 

 

Sox2 and canonical Wnt signaling interact to activate a developmental checkpoint coordinating morphogenesis with mesodermal fate acquisition
Brian A. Kinney, Richard H. Row, Yu-Jung Tseng, Maxwell D. Weidmann, Holger Knaut, Benjamin L. Martin

 

Canonical Wnt-signaling modulates the tempo of dendritic growth of adult-born hippocampal neurons
Jana Heppt, Marie-Theres Wittmann, Jingzhong Zhang, Daniela Vogt-Weisenhorn, Nilima Prakash, Wolfgang Wurst, Makoto Mark Taketo, D. Chichung Lie

 

ATX expression from GFAP+ cells is essential for embryonic development
Ioanna Sevastou, Ioanna Ninou, Vassilis Aidinis

 

 

Kctd15 regulates nephron segment development by repressing Tfap2a activity
Brooke E. Chambers, Eleanor G. Clark, Allison E. Gatz, Rebecca Ann Wingert

 

Heterozygous mutation of Sonic Hedgehog receptor (Ptch) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice
Thomas W. Jackson, Gabriel A. Bendfeldt, Kelby A. Beam, Kylie D. Rock, Scott M. Belcher

 

ARL13B regulates Sonic Hedgehog signaling from outside primary cilia
Eduardo D. Gigante, Megan R. Taylor, Anna A. Ivanova, Richard A. Kahn, Tamara Caspary

 

 

Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis
Bailey A Allard, Wei Wang, Tana S Pottorf, Hammad Mumtaz, Luciane M Silva, Damon T Jacobs, Jinxi Wang, Erin E Bumann, Pamela V Tran

 

Endothelial TGF-β signaling instructs smooth muscle development in the cardiac outflow tract
Giulia L.M. Boezio, Anabela Bensimon-Brito, Janett Piesker, Stefan Guenther, Christian S.M. Helker, Didier Y.R. Stainier

 

NOTCH inhibition promotes myoblast fusion by releasing HEYL repression on TMEM8C regulatory regions in foetal skeletal muscles
Joana Esteves de Lima, Cédrine Blavet, Marie-Ange Bonnin, Estelle Hirsinger, Emmanuelle Havis, Delphine Duprez

 

Modular and distinct PlexinA4/Farp2/Rac1 signaling controls dendrite morphogenesis
Victor Danelon, Ron Goldner, Edward Martinez, Irena Gokhman, Kimberly Wang, Avraham Yaron, Tracy S. Tran

 

Cell-type specific impact of glucocorticoid receptor activation on the developing brain
Cristiana Cruceanu, Leander Dony, Anthi C. Krontira, David S. Fischer, Simone Roeh, Rossella Di Giaimo, Christina Kyrousi, Janine Arloth, Darina Czamara, Silvia Martinelli, Stefanie Wehner, Michael S. Breen, Maik Koedel, Susann Sauer, Monika Rex-Haffner, Silvia Cappello, Fabian J. Theis, Elisabeth B. Binder

 

 

Prenylation of axonally translated proteins controls NGF-dependent axon growth
Emily Scott-Solomon, Rejji Kuruvilla

 

Microglia in the developing retina couple phagocytosis with the progression of apoptosis via P2RY12 signaling
Zachary I Blume, Jared M Lambert, Anna G Lovel, Diana M Mitchell

 

Early postnatal inhibitory circuit development in the mouse medial prefrontal and primary somatosensory cortex
Katerina Kalemaki, Xiaxia Xu, Ileana L. Hanganu-Opatz, Kyriaki Sidiropoulou, Domna Karagogeos

 

Nwd1 regulates neuronal differentiation and migration through purinosome formation in the developing cerebral cortex
Seiya Yamada, Ayaka Sato, Shin-ichi Sakakibara

 

Regulation of canonical Wnt signalling by ciliary protein MKS1 and Ubiquitin Proteasome System component UBE2E1
K. Szymanska, K. Boldt, C.V. Logan, M. Ueffing, E. Zeqiraj, G. Wheway, CA. Johnson

 

Bone morphogenetic protein 4 reduces global H3K4me3 to inhibit proliferation and promote differentiation of human neural stem cells
Sonali Nayak, Benjamin Best, Emily Hayes, Ashorne Mahenthiran, Nitin R Wadhwani, Barbara Mania-Farnell, Rintaro Hashizume, John A Kessler, Charles David James, Tadanori Tomita, Guifa Xi

 

Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish
Mounir El-Maï, Marta Marzullo, Inês Pimenta de Castro, Miguel Godinho Ferreira

 

The Wg and Dpp morphogens regulate gene expression by modulating the frequency of transcriptional bursts
Rachael Bakker, Madhav Mani, Richard W. Carthew

 

Edem1 activity in the fat body regulates insulin signalling and metabolic homeostasis in Drosophila
Himani Pathak, Jishy Varghese

 

ADAM17-triggered TNF signalling protects the ageing Drosophila retina from lipid droplet mediated degeneration
Sonia Muliyil, Clémence Levet, Stefan Düsterhöft, Iqbal Dulloo, Sally Cowley, Matthew Freeman

 

Context-specific functions of Notch in Drosophila blood cell progenitors
DM Blanco-Obregon, MJ Katz, L Durrieu, L Gándara, P Wappner

 

Regulation of BMP Signaling by O-GlcNAcylation
Matthew Moulton, Greg Humphreys, Alexander Kim, Anthea Letsou

 

GLP-1 Notch – LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1
Jian Chen, Ariz Mohammad, Nanette Pazdernik, Huiyan Huang, Beth Bowman, Eric Tycksen, Tim Schedl

 

Raising the Connectome: the emergence of neuronal activity and behavior in C. elegans
Bradly Alicea

 

 

| Morphogenesis & mechanics

Highly coordinated mechanical motion mediated by the microtubule cytoskeleton is a pivotal element of de-novo symmetry breaking in hydra spheroids
Heike Sander, Aravind Pasula, Mathias Sander, Varun Giri, Emmanuel Terriac, Franziska Lautenschlaeger, Albrecht Ott

 

Mechanical control of morphogenesis robustness
Emmanuel Martin, Sophie Theis, Guillaume Gay, Bruno Monier, Magali Suzanne

 

Gradient in cytoplasmic pressure in the germline cells controls overlying epithelial cell morphogenesis
Laurie-Anne Lamire, Pascale Milani, Gael Runel, Annamaria Kiss, Leticia Arias, Blandine Vergier, Pradeep Das, David Cluet, Arezki Boudaoud, Muriel Grammont

 

 

Transcytosis via the late endocytic pathway as a cell morphogenetic mechanism
R Mathew, LD Rios-Barrera, P Machado, Y Schwab, M Leptin

 

Developmental regulation of oocyte lipid uptake via ‘patent’ tricellular junctions in Drosophila epithelium
Sarayu Row, Wu-Min Deng

 

 

Fusion of Drosophila oocytes with specified germline sister cells
Zehra Ali-Murthy, Richard D. Fetter, Thomas B. Kornberg

 

In vivo control of the ezrin/radixin/moesin protein ERM-1 in C. elegans
João J. Ramalho, Ophélie Nicolle, Grégoire Michaux, Mike Boxem

 

Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon navigation
Hiroki Takechi, Satoko Hakeda-Suzuki, Yohei Nitta, Yuichi Ishiwata, Makoto Sato, Atsushi Sugie, Takashi Suzuki

 

FGFR3 is a positive regulator of osteoblast expansion and differentiation during zebrafish skull vault development
Emilie Dambroise, Ivan Ktorza, Alessandro Brombin, Ghaith Abdessalem, Joanne Edouard, Marine Luka, Imke Fiedler, Olivia Binder, Olivier Pelle, E. Elizabeth Patton, Björn Busse, Mickaël Menager, Frederic Sohm, Laurence Legeai-Mallet

 

Loss of Caveolin-1 and caveolae leads to increased cardiac cell stiffness and functional decline of the adult zebrafish heart
Dimitrios Grivas, Álvaro González-Rajal, Carlos Guerrero Rodríguez, Ricardo Garcia, José Luis de la Pompa

 

Epithelial morphogenesis in the perinatal mouse uterus
Zer Vue, Richard Behringer

 

Collective cell sorting requires contractile cortical waves in germline cells
Soline Chanet, Jean-René Huynh

 

Desmosomes pattern cell mechanics to govern epidermal tissue form and function
Joshua A. Broussard, Jennifer L. Koetsier, Kathleen J. Green

 

Cdc42 is required for lymphatic branching, maturation and valve formation during embryonic development
Yixin Jin, Jian Wang, Yang Liu, Rui Wang, Hailin Chen, Hongjiang Si, Sathish Srinivasan, Binu Tharakan, Shenyuan L. Zhang, Mariappan Muthuchamy, David C. Zawieja, Xu Peng

 

 

Myosin X interaction with KIF13B, a crucial pathway for Netrin-1-induced axonal development
Hua-Li Yu, Yun Peng, Yang Zhao, Yong-Sheng Lan, Bo Wang, Lu Zhao, Dong Sun, Jin-Xiu Pan, Zhao-Qi Dong, Lin Mei, Yu-Qiang Ding, Xiao-Juan Zhu, Wen-Cheng Xiong

 

Mutation of the Galectin-3 Glycan Binding Domain (Lgals3-R200S) Enhances Cortical Bone Expansion in Male and Trabecular Bone Mass in Female Mice
Kevin A. Maupin, Daniel Dick, VARI Vivarium, Transgenics Core, Bart O. Williams

 

CRL5-dependent regulation of Arl4c and Arf6 controls hippocampal morphogenesis
Jisoo S. Han, Keiko Hino, Raenier V. Reyes, Cesar P. Canales, Adam M. Miltner, Yasmin Haddadi, Junqing Sun, Chao-Yin Chen, Anna La Torre, Sergi Simó

 

A critical role for MSI1 and MSI2 in photoreceptor morphogenesis
Jesse Sundar, Fatimah Matalkah, Bohye Jeong, Peter Stoilov, Visvanathan Ramamurthy

 

SynGAP splice isoforms differentially regulate synaptic plasticity and dendritic development
Yoichi Araki, Ingie Hong, Timothy R. Gamache, Shaowen Ju, Leonardo Collado-Torres, Joo Heon Shin, Richard L. Huganir

 

PEDF-Rpsa-Itga6 signaling regulates cortical neuronal morphogenesis
Sara M. Blazejewski, Sarah A. Bennison, Ngoc T. Ha, Xiaonan Liu, Trevor H. Smith, Kimberly J. Dougherty, Kazuhito Toyo-oka

 

Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
Jasmin Morandell, Lena A. Schwarz, Bernadette Basilico, Saren Tasciyan, Armel Nicolas, Christoph Sommer, Caroline Kreuzinger, Christoph P. Dotter, Lisa S. Knaus, Zoe Dobler, Emanuele Cacci, Johann G. Danzl, Gaia Novarino

 

Clustered γ-Protocadherins Regulate Cortical Interneuron Programmed Cell Death
Walter Mancia, Julien Spatazza, Benjamin Rakela, Ankita Chatterjee, Viraj Pande, Tom Maniatis, Andrea R. Hasenstaub, Michael P. Stryker, Arturo Alvarez-Buylla

 

 

The gamma-Protocadherins regulate the survival of GABAergic interneurons during developmentally-regulated cell death
Candace H. Carriere, Anson D. Sing, Wendy Xueyi Wang, Brian E. Jones, Yohan Yee, Jacob Ellegood, Julie Marocha, Harinad Maganti, Lola Awofala, Amar Aziz, Jason P. Lerch, Julie L. Lefebvre

 

Ephrin-B2 Paces Neuronal Production in the Developing Neocortex
Anthony Kischel, Christophe Audouard, Mohamad-Ali Fawal, Alice Davy

 

 

| Genes & genomes

Cortical morphology at birth reflects spatio-temporal patterns of gene expression in the fetal brain
Gareth Ball, Jakob Seidlitz, Jonathan O’Muircheartaigh, Ralica Dimitrova, Daphna Fenchel, Antonios Makropoulos, Daan Christiaens, Andreas Schuh, Jonathan Passerat-Palmbach, Lucilio Cordero-Grande, Emer Hughes, Anthony Price, Jo V Hajnal, Daniel Rueckert, Emma Claire Robinson, David Edwards

 

Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells
Fabio M. D’Orazio, Piotr Balwierz, Yixuan Guo, Benjamín Hernández-Rodríguez, Aleksandra Jasiulewicz, Juan M. Vaquerizas, Bradley Cairns, Boris Lenhard, Ferenc Müller

 

Failure to maternally reprogram histone methylation causes developmental delay due to germline transcription in somatic tissues
Brandon S. Carpenter, Teresa W. Lee, Caroline F. Plott, Jovan S. Brockett, Dexter A. Myrick, David J. Katz

 

Chromatin accessibility and histone acetylation in the regulation of competence in early development
Melody Esmaeili, Shelby A. Blythe, John W. Tobias, Kai Zhang, Jing Yang, Peter S. Klein

 

Regulation of human development by ubiquitin chain editing of chromatin remodelers
David B. Beck, Mohammed A. Basar, Anthony J. Asmar, Joyce Thompson, Hirotsugu Oda, Daniela T. Uehara, Ken Saida, Precilla D’Souza, Joann Bodurtha, Weiyi Mu, Kristin W. Barañano, Noriko Miyake, Raymond Wang, Marlies Kempers, Yutaka Nishimura, Satoshi Okada, Tomoki Kosho, Ryan Dale, Apratim Mitra, Ellen Macnamara, Undiagnosed Diseases Network, Naomichi Matsumoto, Johi Inazawa, Magdalena Walkiewicz, Cynthia J. Tifft, Ivona Aksentijevich, Daniel L. Kastner, Pedro P. Rocha, Achim Werner

 

Characterising open chromatin identifies novel cis-regulatory elements important for paraxial mesoderm formation and axis extension
Gi Fay Mok, Leighton Folkes, Shannon Weldon, Eirini Maniou, Victor Martinez-Heredia, Alice Godden, Ruth Williams, Grant Nicholas Wheeler, Simon Moxon, Andrea Munsterberg

 

Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation
Dan Liang, Angela L. Elwell, Nil Aygün, Michael J. Lafferty, Oleh Krupa, Kerry E. Cheek, Kenan P. Courtney, Marianna Yusupova, Melanie E. Garrett, Allison Ashley-Koch, Gregory E. Crawford, Michael I. Love, Luis de la Torre-Ubieta, Daniel H. Geschwind, Jason L. Stein

 

 

The npBAF to nBAF Chromatin Switch Regulates Cell Cycle Exit in the Developing Mammalian Cortex
Simon MG Braun, Ralitsa Petrova, Jiong Tang, Andrey Krokhotin, Erik L Miller, Yitai Tang, Georgia Panagiotakos, Gerald R Crabtree

 

Hmx3a does not require its homeodomain for its essential functions in spinal cord, ear and lateral line development
Samantha J. England, Gustavo A. Cerda, Angelica Kowalchuk, Taylor Sorice, Ginny Grieb, Katharine E. Lewis

 

 

Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors
Shiri Kult, Elazar Zelzer, Tsviya Olender, Marco Osterwalder, Sharon Krief, Ronnie Blecher-Gonen, Shani Ben-Moshe, Lydia Farack, Hadas Keren-Shaul, Dena Leshkowitz, Tomer-Meir Salame, Terence D Capellini, Shalev Itzkovitz, Ido Amit, Axel Visel

 

Discovery of genes required for body axis and limb formation by global identification of retinoic acid regulated epigenetic marks
Marie Berenguer, Karolin F. Meyer, Jun Yin, Gregg Duester

 

The regulation of mammalian maternal-to-embryonic transition by Eukaryotic translation initiation factor 4E
Yan Li, Xuefeng Huang, Jianan Tang, Xu Ji, Miao Liu, Lu Chang, Jing Liu, Yihua Gu, Changgen Shi, Wuhua Ni, Hui-juan Shi, Chris O’Neill, Xingliang Jin

 

 

Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors
Kamryn N Gerner-Mauro, Haruhiko Akiyama, Jichao Chen

 

Discovery of an evolutionarily conserved smooth muscle cell-specific lncRNA CARMN
Kunzhe Dong, Jian Shen, Xiangqin He, Liang Wang, Guoqing Hu, Kirstopher M. Bunting, Rachael Dixon-Melvin, Zeqi Zheng, Hongbo Xin, Meixiang Xiang, Almira Vazdarjanova, Jiliang Zhou

 

Dicer- and BSC-dependent miRNAs during murine anagen development
Neda Vishlaghi, Thomas S. Lisse

 

Extensive nuclear gyration and pervasive non-genic transcription during primordial germ cell development in zebrafish
Stefan Redl, Antonio M. de Jesus Domingues, Stefanie Möckel, Willi Salvenmoser, Maria Mendez-Lago, René F. Ketting

 

Geminin is required for Hox gene regulation to pattern the developing limb
Emily M.A. Lewis, Savita Sankar, Caili Tong, Ethan Patterson, Laura E. Waller, Paul Gontarz, Bo Zhang, David M. Ornitz, Kristen L. Kroll

 

 

Hox-dependent coordination of cardiac progenitor cell patterning and differentiation
Sonia Stefanovic, Brigitte Laforest, Jean-Pierre Desvignes, Fabienne Lescroart, Laurent Argiro, Corinne Maurel-Zaffran, David Salgado, Christopher de Bono, Kristijan Pazur, Magali Théveniau-Ruissy, Christophe Béroud, Michel Pucéat, Anthony Gavalas, Robert G. Kelly, Stéphane Zaffran

 

Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics
David E. Buchholz, Thomas S. Carroll, Arif Kocabas, Xiaodong Zhu, Hourinaz Behesti, Phyllis L. Faust, Lauren Stalbow, Yin Fang, Mary E. Hatten

 

Single cell epigenomic atlas of the developing human brain and organoids
Ryan S. Ziffra, Chang N. Kim, Amy Wilfert, Tychele N. Turner, Maximilian Haeussler, Alex M. Casella, Pawel F. Przytycki, Anat Kreimer, Katherine S. Pollard, Seth A. Ament, Evan E. Eichler, Nadav Ahituv, Tomasz J. Nowakowski

 

High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human embryonic stem cell gastruloid cultures
Kyaw Thu Minn, Yuheng C. Fu, Shenghua He, Steven C. George, Mark A. Anastasio, Samantha A. Morris, Lilianna Solnica-Krezel

 

An atlas of cell types in the mammalian epididymis and vas deferens
Vera D. Rinaldi, Elisa Donnard, Kyle J. Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, Oliver J. Rando

 

The landscape of mouse epididymal cells defined by the single-cell RNA-Seq
Jianwu Shi, Mengmeng Sang, Gangcai Xie, Hao Chen

 

Single-cell RNA-seq reveals endoimmune cells in zebrafish
Yunwei Shi, Peipei Qian, Jiajing Sheng, Xu Zhang, Xiaoning Wang, Jingxiang Zhao, Guanyun Wei, Xia Liu, Gangcai Xie, Dong Liu

 

miR-206 knockout shows it is critical for myogenesis and directly regulates newly identified target mRNAs
Georgiana M. Salant, Kimngan L. Tat, James A. Goodrich, Jennifer F. Kugel

 

Molecular and genetic regulation of pig pancreatic islet cell development
Seokho Kim, Robert L. Whitener, Heshan Peiris, Xueying Gu, Charles A. Chang, Jonathan Y. Lam, Joan Camunas-Soler, Insung Park, Romina J. Bevacqua, Krissie Tellez, Stephen R. Quake, Jonathan R. T. Lakey, Rita Bottino, Pablo J. Ross, Seung K. Kim

 

Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
Michelle M Halstead, Xin Ma, Richard M Schultz, Pablo J Ross

 

Differentiation genes were governed by DNA methylation during hair follicle morphogenesis in Cashmere goat
Shanhe Wang, Fang Li, Jinwang Liu, Yuelang Zhang, Yujie Zheng, Wei Ge, Lei Qu, Xin Wang

 

A single-cell transcriptome atlas during Cashmere goat hair follicle morphogenesis
Wei Ge, Wei-Dong Zhang, Yue-Lang Zhang, Yu-Jie Zheng, Fang Li, Shan-He Wang, Jin-Wang Liu, Shao-Jing Tan, Zi-Hui Yan, Lu Wang, Wei Shen, Lei Qu, Xin Wang

 

A Waddington Epigenetic Landscape for the C. elegans embryo
Ahmed Elewa

 

Three Rules Explain Transgenerational Small RNA Inheritance in C. elegans
Leah Houri-Ze’evi, Olga Antonova, Oded Rechavi

 

Recovery from transgenerational RNA silencing is driven by gene-specific homeostasis
Sindhuja Devanapally, Pravrutha Raman, Samual Allgood, Farida Ettefa, Maigane Diop, Mary Chey, Yixin Lin, Yongyi E Cho, Rui Yin, Antony M Jose

 

mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage
Dylan M. Parker, Lindsay P. Winkenbach, Samuel P. Boyson, Matthew N. Saxton, Camryn Daidone, Zainab A. Al-Mazaydeh, Marc T. Nishimura, Florian Mueller, Erin Osborne Nishimura

 

Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility
Elizabeth Eck, Jonathan Liu, Maryam Kazemzadeh-Atoufi, Sydney Ghoreishi, Shelby A Blythe, Hernan Garcia

 

Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
Bumsik Cho, Sang-Ho Yoon, Daewon Lee, Ferdinand Koranteng, Sudhir Gopal Tattikota, Nuri Cha, Mingyu Shin, Hobin Do, Yanhui Hu, Sue Young Oh, Seok Jun Moon, Norbert Perrimon, Jin-Wu Nam, Jiwon Shim

 

 

Condensin I subunit Cap-G is essential for proper gene expression during the maturation of post-mitotic neurons
Amira Hassan, Pablo Araguas Rodriguez, Stefan K. Heidmann, Emma L. Walmsley, Gabriel N. Aughey, Tony D. Southall

 

An interaction network of RNA-binding proteins involved in Drosophila oogenesis
Prashali Bansal, Johannes Madlung, Kristina Schaaf, Boris Macek, Fulvia Bono

 

sisterless A is required for the activation of Sex lethal in the germline
Raghav Goyal, Ellen Baxter, Mark Van Doren

 

 

| Stem cells, regeneration & disease modelling

Msps Governs Acentrosomal Microtubule Assembly and Reactivation of Quiescent Neural Stem Cells
Qiannan Deng, Ye Sing Tan, Liang Yuh Chew, Hongyan Wang

 

 

dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye
Krista M. Angileri, Jeffrey M. Gross

 

Extracellular caspase-1 regulates hair follicle stem cell migration during wound-healing
Subhasri Ghosh, Akhil SHP Ananthan, Sunny Kataria, Neha Pincha, Abhik Dutta, Srilekha Athreya, Aishwarya Bhosale, Rakesh Dey, Colin Jamora

 

Embryonic signals perpetuate polar-like trophoblast stem cells and pattern the blastocyst axis.
Javier Frias Aldeguer, Maarten Kip, Judith Vivie, Linfeng Li, Anna Alemany, Jeroen Korving, Frank Darmis, Alexander van Oudenaarden, Niels Geijsen, Nicolas C Rivron

 

Sox2 modulation increases naïve pluripotency plasticity
Kathryn Tremble, Giuliano G. Stirparo, Lawrence E. Bates, Katsiaryna Maskalenka, Hannah T. Stuart, Kenneth Jones, Amanda Andersson-Rolf, Aliaksandra Radzisheuskaya, Bon-Kyoung Koo, Paul Bertone, José C. R. Silva

 

Oct4 regulates embryonic pluripotency via metabolic mechanisms and Stat3 signalling.
Giuliano G Stirparo, Agata Kurowski, Stanley E Strawbridge, Hannah Stuart, Thorsten E Boroviak, Ayaka Yanagida, Jennifer Nichols

 

Oct4-mediated inhibition of Lsd1 activity promotes the active and primed state of pluripotency enhancers
Lama AlAbdi, Debapriya Saha, Ming He, Mohd Saleem Dar, Sagar M. Utturkar, Putu Ayu Sudyanti, Stephen McCune, Brice H. Spears, James A. Breedlove, Nadia A. Lanman, Humaira Gowher

 

Neural stem cells traffic functional mitochondria via extracellular vesicles to correct mitochondrial dysfunction in target cells
Luca Peruzzotti-Jametti, Joshua D Bernstock, Giulia Manferrari, Rebecca Rogall, Erika Fernandez-Vizarra, James C Williamson, Alice Braga, Aletta Van den Bosch, Tommaso Leonardi, Agnes Kittel, Cristiane Beninca, Nunzio Vicario, Sisareuth Tan, Carlos Bastos, Iacopo Bicci, Nunzio Iraci, Jayden A Smith, Paul J Lehner, Edit I Buzas, Nuno Faria, Massimo Zeviani, Christian Frezza, Alain Brisson, Nicholas J Matheson, Carlo Viscomi, Stefano Pluchino

 

Mechanical Instability of Adherens Junctions Overrides Intrinsic Quiescence of Hair Follicle Stem Cells
Ritusree Biswas, Avinanda Banerjee, Sergio Lembo, Zhihai Zhao, Vairavan Lakshmanan, Manando Nakasaki, Vassily Kutyavin, Graham Wright, Dasaradhi Palakodeti, Robert Ross, Colin Jamora, Valeri Vasioukhin, Yan Jie, Srikala Raghavan

 

Myofiber stretch induces tensile and shear deformation of muscle stem cells in their native niche
Mohammad Haroon, Jenneke Klein-Nulend, Astrid D. Bakker, Jianfeng Jin, Carla Offringa, Fabien Le Grand, Lorenzo Giordani, Karen J. Liu, Robert D. Knight, Richard T. Jaspers

 

A susceptibility locus on chromosome 13 profoundly impacts the stability of genomic imprinting in mouse pluripotent stem cells
Emily Swanzey, Thomas F. McNamara, Effie Apostolou, Mamta Tahiliani, Matthias Stadtfeld

 

USP9X deubiquitinase couples the pluripotency network and cell metabolism to regulate ESC differentiation potential
Maud de Dieuleveult, Marjorie Leduc, Eralda Salataj, Céline Ransy, Julien Dairou, Kengo Homma, Morgane Le Gall, Pascale Bossard, Anne Lombès, Frédéric Bouillaud, Laure Ferry, Pierre-Antoine Defossez, Jean-Charles Cadoret, Hidenori Ichijo, Stephen A. Wood, François Guillonneau, Ralf Dressel, Benoit Miotto

 

 

Quantitative and molecular differences distinguish adult human medullary and extramedullary haematopoietic stem and progenitor cell landscapes
Nicole Mende, Hugo P Bastos, Antonella Santoro, Kendig Sham, Krishnaa T. Mahbubani, Abbie Curd, Hitoshi Takizawa, Nicola K Wilson, Bertie Göttgens, Kourosh Saeb-Parsy, Elisa Laurenti

 

USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells
Paul van den Berk, Cesare Lancini, Carlos Company, Michela Serresi, Danielle Hulsman, Colin Pritchard, Ji-Ying Song, Matthias Jürgen Schmitt, Ellen Tanger, Ivo J. Huijbers, Heinz Jacobs, Maarten van Lohuizen, Gaetano Gargiulo, Elisabetta Citterio

 

Cell signaling coordinates global Polycomb Repressive Complex 2 recruitment and gene expression in murine embryonic stem cells
Mohammad B. Aljazi, Yuen Gao, Yan Wu, George I. Mias, Jin He

 

Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells
Helena G. Asenjo, Amador Gallardo, Lourdes López-Onieva, Irene Tejada, Jordi Martorell-Marugán, Pedro Carmona-Sáez, David Landeira

 

Single Cell Analysis Reveals Partial Reactivation of X-chromosome Instead of Chromosome-wide Dampening in Naïve Human Pluripotent Stem Cells
S Mandal, D Chandel, H Kaur, S Majumdar, M Arava, S Gayen

 

ATR expands embryonic stem cell fate potential in response to replication stress
Sina Atashpaz, Sara Samadi Shams, Javier Martin Gonzalez, Endre Sebestyén, Negar Arghavanifard, Andrea Gnocchi, Eliene Albers, Simone Minardi, Giovanni Faga, Paolo Soffientini, Elisa Allievi, Valeria Cancila, Angela Bachi, Oscar Fernandez-Capetillo, Claudio Tripodo, Francesco Ferrari, Andrés Joaquin López-Contreras, Vincenzo Costanzo

 

Characterization of human-iPSCs derived spinal motor neurons by single-cell RNA sequencing
Louise Thiry, Regan Hamel, Stefano Pluchino, Thomas Durcan, Stefano Stifani

 

Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells
Steven Vermeulen, Nadia Roumans, Floris Honig, Aurélie Carlier, Dennie GAJ Hebels, Aysegul Dede Eren, Peter ten Dijcke, Aliaksei Vasilevich, Jan de Boer

 

Scalable generation of mesenchymal stem cells and adipocytes from human pluripotent stem cells
Manale Karam, Ihab Younis, Essam M. Abdelalim

 

Over-Confluence of expanded bone marrow mesenchymal stem cells ameliorates their chondrogenic capacity in 3D cartilage tissue engineering
Damien Tucker, Karen Still, Ashley Blom, Anthony P. Hollander, Wael Kafienah

 

Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA lnc-Rewind in muscle stem cells
Andrea Cipriano, Martina Macino, Giulia Buonaiuto, Tiziana Santini, Beatrice Biferali, Giovanna Peruzzi, Alessio Colantoni, Chiara Mozzetta, Monica Ballarino

 

 

Dissecting endothelial to haematopoietic stem cell transition by single-cell transcriptomic and functional analyses
Siyuan Hou, Zongcheng Li, Xiaona Zheng, Yun Gao, Ji Dong, Yanli Ni, Xiaobo Wang, Yunqiao Li, Xiaochen Ding, Zhilin Chang, Shuaili Li, Yuqiong Hu, Xiaoying Fan, Yu Hou, Lu Wen, Bing Liu, Fuchou Tang, Yu Lan

 

Transcription factors involved in stem cell maintenance are downstream of Slug/Snail2 and repressed by TGF-β in bronchial epithelial progenitors from Chronic Obstructive Pulmonary Disease
Pierre de la Grange, Ariane Jolly, Charlotte Courageux, Chamseddine Ben Brahim, Pascale Leroy

 

Ubiquitous overexpression of CXCL12 confers radiation protection and enhances mobilization of hematopoietic stem and progenitor cells
Smrithi Rajendiran, Stephanie Smith-Berdan, Leo Kunz, Maurizio Risolino, Licia Selleri, Timm Schroeder, E Camilla Forsberg

 

Modulation of the canonical Wnt activity by androgen signaling in prostate epithelial basal stem cells
Yueli Liu, Jiawen Wang, Corrigan Horton, Sol Katzman, Tao Cai, Zhu A. Wang

 

Regeneration in the adult Drosophila brain
Kassi L. Crocker, Khailee Marischuk, Stacey A. Rimkus, Hong Zhou, Jerry C.P. Yin, Grace Boekhoff-Falk

 

Wnt signaling determines body axis polarity in regenerating Hydra tissue
Rui Wang, Robert E. Steele, Eva-Maria S. Collins

 

ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration
Alla Aharonov, Avraham Shakked, Kfir Baruch Umansky, Alon Savidor, David Kain, Daria Lendengolts, Or-Yam Revach, Yuka Morikawa, Jixin Dong, Yishai Levin, Benjamin Geiger, James F. Martin, Eldad Tzahor

 

Protrudin functions as a scaffold in the endoplasmic reticulum to support axon regeneration in the adult central nervous system
Veselina Petrova, Craig S. Pearson, James R. Tribble, Andrea G. Solano, Evan Reid, Pete A. Williams, Herbert M. Geller, Richard Eva, James W. Fawcett

 

Isolation and long-term expansion of a single adult human renal epithelial cell with efficient kidney regeneration capacity
Yujia Wang, Zixian Zhao, Qiwang Ma, Hao Nie, Yufen Sun, Xiaobei Feng, Ting Zhang, Yu Ma, Jing Nie, Wei Zuo

 

Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18
Huan Liu, Kaylia Duncan, Annika Helverson, Priyanka Kumari, Camille Mumm, Yao Xiao, Jenna C Carlson, Fabrice Darbellay, Axel Visel, Elizabeth Leslie, Patrick Breheny, Albert J Erives, Robert Cornell

 

AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication
Kunihiko Yamashiro, Kei Hori, Esther S.K. Lai, Ryo Aoki, Kazumi Shimaoka, Saki F. Egusa, Asami Sakamoto, Manabu Abe, Kenji Sakimura, Takaki Watanabe, Naofumi Uesaka, Masanobu Kano, Mikio Hoshino

 

Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development
Adriana C. Gittenberger-de Groot, Joshua C. Peterson, Lambertus J. Wisse, Arno A.W. Roest, Robert E. Poelmann, Regina Bökenkamp, Nynke J. Elzenga, Mark Hazekamp, Margot M. Bartelings, Monique R.M. Jongbloed, Marco C. DeRuiter

 

Modelling and rescue of RP2 Retinitis Pigmentosa using iPSC Derived Retinal Organoids
Amelia Lane, Katarina Jovanovic, Ciara Shortall, Daniele Ottaviani, Anna Brugulat-Panes, Arpad Palfi, Naomi Chadderton, G. Jane Farrar, Alison J. Hardcastle, Michael E Cheetham

 

Human iPSC modeling elucidates mutation-specific responses to gene therapy in a genotypically diverse dominant maculopathy
Divya Sinha, Benjamin G Steyer, Pawan K Shahi, Katherine Mueller, Rasa Valiauga, Kimberly L Edwards, Cole Bacig, Stephanie S Steltzer, Sandhya Srinivasan, Amr Abdeen, Evan Cory, Viswesh Periyasamy, Alireza Fotuhi Siahpirani, Sushmita Roy, Bikash R Pattnaik, Krishanu Saha, David M Gamm

 

Carbamazepine restores neuronal signaling, protein synthesis and cognitive function in a mouse model of fragile X syndrome
Qi Ding, Fan Zhang, Yue Feng, Hongbing Wang

 

Variant-specific changes in persistent or resurgent Na+ current in SCN8A-EIEE13 iPSC-derived neurons
Andrew M. Tidball, Luis F. Lopez-Santiago, Yukun Yuan, Trevor W. Glenn, Joshua L. Margolis, J. Clayton Walker, Emma G. Kilbane, Lori L. Isom, Jack M Parent

 

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids
Ivanyuk Dina, Maria Jose Perez, Vasiliki Panagiotakopoulou, Gabriele Di Napoli, Dario Brunetti, Rawaa Al-Shaana, Stephan A. Kaeser, Mathias Jucker, Massimo Zeviani, Carlo Viscomi, Michela Deleidi

 

Human iPS Cells Derived Skeletal Muscle Progenitor Cells Promote Myoangiogenesis and Restore Dystrophin in Duchenne Muscular Dystrophic Mice
Wanling Xuan, Mahmood Khan, Muhammad Ashraf

 

 

| Plant development

 

 

Suspensor-derived somatic embryogenesis in Arabidopsis
Tatyana Radoeva, Catherine Albrecht, Marcel Piepers, Sacco de Vries, Dolf Weijers

 

Maternal genome dominance in early plant embryogenesis
Jaime Alaniz-Fabián, Daoquan Xiang, Gerardo Del Toro-De León, Axel Orozco-Nieto, Peng Gao, Andrew Sharpe, Leon V. Kochian, Gopalan Selvaraj, Nathan Springer, Cei Abreu-Goodger, Raju Datla, C. Stewart Gillmor

 

Strigolactone defective mutants of Arabidopsis exhibit delayed sepal senescence
Xi Xu, Rubina Jibran, Yanting Wang, Lemeng Dong, Kristyna Flokova, Azadeh Esfandiari, Andrew McLachlan, Axel Heiser, Andrew Sutherland-Smith, Harro Bouwmeester, Paul Dijkwel, Donald Hunter

 

Vacuolar sucrose homeostasis is critical for development, seed properties and survival of dark phases of Arabidopsis
Duc Phuong Vu, Cristina Martins Rodrigues, Benjamin Jung, Garvin Meissner, Patrick A.W. Klemens, Daniela Holtgräwe, Lisa Fürtauer, Thomas Nägele, Petra Nieberl, Benjamin Pommerrenig, H. Ekkehard Neuhaus

 

Variation in the expression of a transmembrane protein influences cell growth in Arabidopsis thaliana petals by altering auxin availability
Charlotte N. Miller, Jack Dumenil, Caroline Smith, Fu Hao Lu, Neil McKenzie, Volodymyr Chapman, Joshua Ball, Mathew Box, Michael Bevan

 

Pollen tube-triggered accumulation of NORTIA at the filiform apparatus facilitates fertilization in Arabidopsis thaliana
Jing Yuan, Yan Ju, Daniel S. Jones, Weiwei Zhang, Noel Lucca, Christopher J. Staiger, Sharon A. Kessler

 

An Arabidopsis AT-hook motif nuclear protein mediates somatic embryogenesis and coinciding genome duplication
Omid Karami, Arezoo Rahimi, Patrick Mak, Anneke Horstman, Kim Boutilier, Monique Compier, Bert van der Zaal, Remko Offringa

 

ETHYLENE RESPONSE FACTOR 115 integrates jasmonate and cytokinin signaling machineries to repress adventitious rooting in Arabidopsis
Abdellah Lakehal, Asma Dob, Zahra Rahneshan, Ondřej Novák, Sacha Escamez, Sanaria Alallaq, Miroslav Strnad, Hannele Tuominen, Catherine Bellini

 

Arabidopsis ERF4 and MYB52 Transcription Factors Play Antagonistic Roles in Regulating Homogalacturonan De-methylesterification in Seed Coat Mucilage
Anming Ding, Xianfeng Tang, Linhe Han, Jianlu Sun, Angyan Ren, Jinhao Sun, Zongchang Xu, Ruibo Hu, Gongke Zhou, Yingzhen Kong

 

An Arabidopsis long noncoding RNA modulates the transcriptome through interactions with a network of splicing factors
Richard Rigo, Jérémie Bazin, Natali Romero-Barrios, Michaël Moison, Leandro Lucero, Aurélie Christ, Moussa Benhamed, Thomas Blein, Stéphanie Huguet, Céline Charon, Martin Crespi, Federico Ariel

 

CHLOROPLAST UNUSUAL POSITIONING 1 is a new type of actin nucleation factor in plants
Sam-Geun Kong, Atsushi Shimada, Saku T. Kijima, Keiko Hirose, Kaoru Katoh, Jeongsu Ahn, Takeshi Higa, Akira Takano, Yuki Nakamura, Noriyuki Suetsugu, Daisuke Kohda, Taro Q. P. Uyeda, Masamitsu Wada

 

Disruption of NAP1 genes supresses the fas1 mutant phenotype and enhances genome stability
Karolína Kolářová, Martina Nešpor Dadejová, Tomáš Loja, Eva Sýkorová, Martina Dvořáčková

 

COP1 destabilizes DELLA proteins in Arabidopsis
Noel Blanco-Touriñán, Martina Legris, Eugenio G. Minguet, Cecilia Costigliolo-Rojas, María A. Nohales, Elisa Iniesto, Marta García-León, Manuel Pacín, Nicole Heucken, Tim Blomeier, Antonella Locascio, Martin Černý, David Esteve-Bruna, Mónica Díez-Díaz, Břetislav Brzobohatý, Henning Frerigmann, Matías D. Zurbriggen, Steve A. Kay, Vicente Rubio, Miguel A. Blázquez, Jorge J. Casal, David Alabadí

 

A suppressor of axillary meristem maturation promotes longevity in flowering plants
Omid Karami, Arezoo Rahimi, Majid Khan, Marian Bemer, Rashmi R. Hazarika, Patrick Mak, Monique Compier, Vera van Noort, Remko Offringa

 

The Arabidopsis N-terminal Acetyltransferase NAA50 Regulates Plant Growth and Defense
Matthew Neubauer, Roger W. Innes

 

Loss of AUXIN RESPONSE FACTOR 4 function alters plant growth, stomatal function and improves tomato tolerance to salinity and osmotic stress
Sarah Bouzroud, Karla Gasparini, Guojian Hu, Maria Antonia Machado Barbosa, Bruno Luan Rosa, Mouna Fahr, Najib Bendaou, Mondher Bouzayen, Agustin Zsögön, Abdelaziz Smouni, Mohamed Zouine

 

Mutations in the tomato gibberellin receptors suppresses xylem proliferation and reduces water loss under water-deficit conditions
Natanella Illouz-Eliaz, Idan Nissan, Ido Nir, Uria Ramon, Hagai Shohat, David Weiss

 

Sucrose promotes etiolated stem branching through activation of cytokinin accumulation followed by vacuolar invertase activity
Bolaji Babajide Salam, Francois Barbier, Raz Danieli, Carmit Ziv, Lukáš Spíchal, Paula Teper-Bamnolker, Jiming Jiang, Naomi Ori, Christine Beveridge, Dani Eshel

 

Vernalization alters sugar beet (Beta vulgaris) sink and source identities and reverses phloem translocation from taproots to shoots
Cristina Martins Rodrigues, Christina Müdsam, Isabel Keller, Wolfgang Zierer, Olaf Czarnecki, José María Corral, Frank Reinhardt, Petra Nieberl, Frederik Sommer, Michael Schroda, Timo Mühlhaus, Karsten Harms, Ulf-Ingo Flügge, Uwe Sonnewald, Wolfgang Koch, Frank Ludewig, H. Ekkehard Neuhaus, Benjamin Pommerrenig

 

Silencing of TaCKX1 mediates expression of other TaCKX genes to increase grain yield in wheat
Bartosz Jabłoński, Hanna Ogonowska, Karolina Szala, Andrzej Bajguz, Wacław Orczyk, Anna Nadolska-Orczyk

 

Silencing of Mu elements in maize involves distinct populations of small RNAs and distinct patterns of DNA methylation
Diane Burgess, Hong Li, Meixia Zhao, Sang Yeol Kim, Damon Lisch

 

Variation in maize chlorophyll biosynthesis alters plant architecture
Rajdeep S. Khangura, Gurmukh S. Johal, Brian P. Dilkes

 

 

Accurate and Versatile 3D Segmentation of Plant Tissues at Cellular Resolution
Adrian Wolny, Lorenzo Cerrone, Athul Vijayan, Rachele Tofanelli, Amaya Vilches Barro, Marion Louveaux, Christian Wenzl, Susanne Steigleder, Constantin Pape, Alberto Bailoni, Salva Duran-Nebreda, George Bassel, Jan U. Lohmann, Fred A. Hamprecht, Kay Schneitz, Alexis Maizel, Anna Kreshuk

 

Design of a biosensor for direct visualisation of auxin
Ole Herud-Sikimic, Andre C Stiel, Marina Ortega-Perez, Sooruban Shanmugaratnam, Birte Hoecker, Gerd C Juergens

 

 

Evo-devo & evo

 

 

Evolution of vertebrate gill covers via shifts in an ancient Pou3f3 enhancer
Lindsey Barske, Peter Fabian, Christine Hirschberger, David Jandzik, Tyler Square, Pengfei Xu, Nellie Nelson, Haoze Vincent Yu, Daniel M. Medeiros, J. Andrew Gillis, J. Gage Crump

 

The TMJ disc is a common ancestral feature in all mammals, as evidenced by the presence of a rudimentary disc during monotreme development
Neal Anthwal, Abigail S Tucker

 

 

NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis
Océane Tournière, David Dolan, Gemma Sian Richards, Kartik Sunagar, Yaara Y Columbus-Shenkar, Yehu Moran, Fabian Rentzsch

 

Hedgehog signaling is required for endomesodermal patterning and germ cell development in Nematostella vectensis
Cheng-Yi Chen, Sean A. McKinney, Lacey R. Ellington, Matthew C. Gibson

 

Growth of the Fucus embryo: insights into wall-mediated cell expansion through mechanics and transcriptomics
Marina Linardić, Shawn J Cokus, Matteo Pellegrini, Siobhan Ariel Braybrook

 

Variation in a pleiotropic regulatory module drives evolution of head shape and eye size in Drosophila
Elisa Buchberger, Anıl Bilen, Sanem Ayaz, David Salamanca, Cristina Matas de las Heras, Armin Niksic, Isabel Almudi, Montserrat Torres-Oliva, Fernando Casares, Nico Posnien

 

The conserved regulatory basis of mRNA contributions to the early Drosophila embryo differs between the maternal and zygotic genomes
Charles S. Omura, Susan E. Lott

 

An ancient satellite repeat controls gene expression and embryonic development in Aedes aegypti through a highly conserved piRNA
Rebecca Halbach, Pascal Miesen, Joep Joosten, Ezgi Taşköprü, Bas Pennings, Chantal B.F. Vogels, Sarah H. Merkling, Constantianus J. Koenraadt, Louis Lambrechts, Ronald P. van Rij

 

 

A long tail of truth and beauty: The developmental basis of complexity, symmetry, and beauty in the evolution of the peacock’s tail.
Rama Shankar Singh, Santosh Jagadeeshan

 

 

Molecular mechanism underlying venation patterning in butterflies
Tirtha Das Banerjee, Antónia Monteiro

 

Perfect mimicry between Heliconius butterflies is constrained by genetics and development
Steven M Van Belleghem, Paola A. Alicea Roman, Heriberto Carbia Gutierrez, Brian A. Counterman, Riccardo Papa

 

Developmental hourglass and heterochronic shifts in fin and limb development
Koh Onimaru, Kaori Tatsumi, Chiharu Tanegashima, Mitsutaka Kadota, Osamu Nishimura, Shigehiro Kuraku

 

Evolution of gastrointestinal tract morphology and plasticity in cave-adapted Mexican tetra, Astyanax mexicanus
Misty R. Riddle, Fleur Damen, Ariel Aspiras, Julius A. Tabin, Suzanne McGaugh, Clifford J. Tabin

 

A practical staging atlas to study embryonic development of Octopus vulgaris under controlled laboratory conditions
Astrid Deryckere, Ruth Styfhals, Erica A.G. Vidal, Eduardo Almansa, Eve Seuntjens

 

Transcriptome analysis reveals evolutionary co-option of neural development and signaling genes for the wing pigmentation pattern of the polka-dotted fruit fly
Yuichi Fukutomi, Shu Kondo, Atsushi Toyoda, Shuji Shigenobu, Shigeyuki Koshikawa

 

Millipede genomes reveal unique adaptation of genes and microRNAs during myriapod evolution
Zhe Qu, Wenyan Nong, Wai Lok So, Tom Barton-Owen, Yiqian Li, Chade Li, Thomas C.N. Leung, Tobias Baril, Annette Y.P. Wong, Thomas Swale, Ting-Fung Chan, Alexander Hayward, Sai-Ming Ngai, Jerome H.L. Hui

 

Temperature change has the same effect as genetic variation on a morphological trait involved in reproductive isolation between Drosophila sister species
Alexandre E Peluffo, Mehdi Hamdani, Alejandra Vargas-Valderrama, Jean R David, Francois Mallard, Francois Graner, Virginie Courtier-Orgogozo

 

Three genomes of Osteoglossidae shed light on ancient teleost evolution
Shijie Hao, Kai Han, Lingfeng Meng, Xiaoyun Huang, Chengcheng Shi, Mengqi Zhang, Yilin Wang, Qun Liu, Yaolei Zhang, Inge Seim, Xun Xu, Xin Liu, Guangyi Fan

 

On the origin and evolution of RNA editing in metazoans
Qiye Li, Pei Zhang, Ji Li, Hao Yu, Xiaoyu Zhan, Yuanzhen Zhu, Qunfei Guo, Huishuang Tan, Nina Lundholm, Lydia Garcia, Michael D. Martin, Meritxell Antó Subirats, Yi-Hsien Su, Iñaki Ruiz-Trillo, Mark Q. Martindale, Jr-Kai Yu, M. Thomas P. Gilbert, Guojie Zhang

 

A rapidly evolved shift in life history timing during ecological speciation is driven by the transition between developmental phases
Thomas HQ Powell, Andrew D Nguyen, Qinwen Xia, Jeffrey L Feder, Gregory J Ragland, Daniel A Hahn

 

CRISPR Mutants of Three Y Chromosome Genes Suggest Gradual Evolution of Fertility Functions in Drosophila melanogaster
Yassi Hafezi, Samantha R. Sruba, Steven R. Tarrash, Mariana F. Wolfner, Andrew G. Clark

 

 

Cell biology

 

Drosophila dTBCE recruits tubulin around chromatin to promote mitotic spindle assembly
Mathieu Métivier, Emmanuel Gallaud, Aude Pascal, Jean-Philippe Gagné, Guy G. Poirier, Denis Chrétien, Romain Gibeaux, Laurent Richard-Parpaillon, Christelle Benaud, Régis Giet

 

Acto-myosin network geometry defines centrosome position
Ana Joaquina Jimenez, Chiara de Pascalis, Gaelle Letort, Benoit Vianay, Robert D. Goldman, Michel Bornens, Matthieu Piel, Laurent Blanchoin, Manuel Théry

 

 

The mouse Balbiani body maintains primordial follicle quiescence via RNA storage
Lei Lei, Kanako Ikami, Haley Abbott, Shiying Jin

 

Shikonin induces odontoblastic differentiation of dental pulp stem cells via AKT–mTOR signaling in the presence of CD44
Naoki Umemura, Kunihiro Kajiura, Emika Ohkoshi, Takahisa Ohta, Nobuo Kondoh, Satoshi Kawano

 

N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells
Jiang-Zhou Yu, Jennifer Wang, Steven D. Sheridan, Roy H. Perlis, Mark M. Rasenick

 

A paralog-specific role of the COPI pathway in the neuronal differentiation of murine pluripotent cells
Manu Goyal, Xiyan Zhao, Mariya Bozhinova, Karla Lisette Andrade López, Cilia de Heus, Sandra Schulze-Dramac, Michaela Müller-McNicoll, Judith Klumperman, Julien Béthune

 

Regulation of the time when cells commit to terminally differentiate controls the number of differentiated cells
Michael L Zhao, Atefeh Rabiee, Kyle M Kovary, Zahra Bahrami-Nejad, Brooks Taylor, Mary N Teruel

 

Mechanical stretch sustains myofibroblast phenotype and function in microtissues through latent TGF-β1 activation
Matthew Walker, Michel Godin, Andrew E. Pelling

 

Dietary supplementation with PUFAs rescues the eggshell defects caused by seipin mutations in C. elegans
Xiaofei Bai, Leng-Jie Huang, Sheng-Wen Chen, Ben Nebenfuehr, Brian Wysolmerski, Jui-Ching Wu, Sara K. Olson, Andy Golden, Chao-Wen Wang

 

The highly expressed lipid buffer FABP4 enforces adipocyte cell identity by driving the initial cell differentiation process
Zahra Bahrami-Nejad, Tinghuan Chen, Stefan Tholen, Atefeh Rabiee, Michael L. Zhao, Ewa Bielczyk-Macynzka, Fredric B. Kraemer, Mary N. Teruel

 

 

Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth cones
Tanushree Kundu, Priyanka Dutta, Dhriti Nagar, Sankar Maiti, Aurnab Ghose

 

The somatic Golgi nucleates microtubules that are directed by Kinesin-2 to maintain microtubule polarity within neurons
Amrita Mukherjee, Paul Brooks, Fred Bernard, Antoine Guichet, Paul T. Conduit

 

KLF4 coordinates corneal epithelial apicobasal polarity and plane of cell division, and is downregulated in ocular surface squamous neoplasia
Anil Tiwari, Sudha Swamynathan, Vishal Jhanji, Shivalingappa K. Swamynathan

 

Aurora B and Condensin are dispensable for chromosome arm and telomere separation during meiosis II
Julien Berthezene, Céline Reyes, Tong Li, Stéphane Coulon, Pascal Bernard, Yannick Gachet, Sylvie Tournier

 

Extracellular TGF-β downregulates the expression of Wnt transcription factor TCF7L2/TCF4 in mesenchymal stromal cells and fibroblasts
Osvaldo Contreras, Hesham Soliman, Marine Theret, Fabio M. Rossi, Enrique Brandan

 

Reduced PABPN1 levels causes cytoskeleton disorganization and aberrant differentiation
Cyriel Sebastiaan Olie, Erik van der Wal, Cikes Domagoj, Loes Maton, Jessica C. de Greef, I-Hsuan Lin, Yi-Fan Chen, Elsayad Kareem, Josef M. Penninger, Benedikt M. Kessler, Vered Raz

 

WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility
Shail Kabrawala, Margaret D. Zimmer, Kenneth G. Campellone

 

Linker histone H1 determines cell stiffness and differentiation
Marie Kijima, Hiroyuki Yamagishi, Riho Kawano, Tomoki Konishi, Takuya Okumura, Masanori Hayase, Ryushin Mizuta

 

Machine learning approach reveals heterogeneous responses to FAK and Rho GTPases inhibition on smooth muscle spheroid formation
Kalyanaraman Vaidyanathan, Chuangqi Wang, Yudong Yu, Amanda Krajnik, Moses Choi, Bolun Lin, John Kolega, Kwonmoo Lee, Yongho Bae

 

VARIATION AND SELECTION IN AXON NAVIGATION THROUGH MICROTUBULE-DEPENDENT STEPWISE GROWTH CONE ADVANCE
Steven G Turney, Indra Chandrasekar, Mostafa Ahmed, Robert M Rioux, George M Whitesides, Paul C Bridgman

 

 

Modelling

 

Computational modelling of cambium activity provides a regulatory framework for simulating radial plant growth
Ivan Lebovka, Bruno Hay Mele, Alexandra Zakieva, Nial Gursanscky, Roeland Merks, Thomas Greb

 

Discovery of the spatial pattern of prickles on the stem of the rose and the mathematical model of the pattern
Kazuaki Amikura, Hiroshi Ito

 

Geometric models for robust encoding of dynamical information into embryonic patterns
Laurent Jutras-Dubé, Ezzat El-Sherif, Paul François

 

Epithelial organ shape is generated by patterned actomyosin contractility and maintained by the extracellular matrix
Ali Nematbakhsh, Megan Levis, Nilay Kumar, Weitao Chen, Jeremiah Zartman, Mark Alber

 

Modelling the emergence of whisker barrels
Sebastian S James, Leah A Krubitzer, Stuart P Wilson

 

Multiscale modelling of motility wave propagation in cell migration
Hamid Khataee, Zoltan Neufeld, Andras Czirok

 

New mathematical modelling tools for co-culture experiments: when do we need to explicitly account for signalling molecules?
Wang Jin, Haolu Wang, Xiaowen Liang, Michael S Roberts, Matthew J Simpson

 

A Reaction-Diffusion Network model predicts a dual role of Cactus/IκB to regulate Dorsal/NFκB nuclear translocation in Drosophila
Claudio D. T. Barros, Maira A. Cardoso, Paulo M. Bisch, Helena M. Araujo, Francisco J P Lopes

 

Perturbation analysis of a multi-morphogen Turing Reaction-Diffusion stripe patterning system reveals key regulatory interactions
Andrew D. Economou, Nicholas A.M. Monk, Jeremy B.A. Green

 

An Active Chemo-mechanical Model to Predict Adhesion and Microenvironmental Regulation of 3D Cell Shapes
Xingyu Chen, Veronika te Boekhorst, Eoin McEvoy, Peter Friedl, Vivek B. Shenoy

 

Computational estimates of mechanical constraints on cell migration through extracellular matrix
Ondrej Maxian, Alex Mogilner, Wanda Strychalski

 

Cell polarisation in a bulk-surface model can be driven by both classic and non-classic Turing instability
Johannes Borgqvist, Adam Malik, Carl Lundholm, Anders Logg, Philip Gerlee, Marija Cvijovic

 

Cytoskeleton polarity is essential in determining orientational order in basal bodies of multi-ciliated cells
Toshinori Namba, Shuji Ishihara

 

Leader-cell-driven epithelial sheet fingering
Yanjun Yang, Herbert Levine

 

 

Tools & resources

A plug and play microfluidic platform for standardized sensitive low-input Chromatin Immunoprecipitation
René A.M. Dirks, Peter Thomas, Robert C. Jones, Hendrik G. Stunnenberg, Hendrik Marks

 

A chemical tool for improved culture of human pluripotent stem cells
Laurence Silpa, Maximilian Schuessler, Gu Liu, Marcus Olivecrona, Lucia Groizard-Payeras, Elizabeth Couper, Carole J. R. Bataille, Mark Stevenson, Len W. Seymour, Stephen G. Davies, William S. James, Sally A. Cowley, Angela J. Russell

 

CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos
Gopal Kushawah, Joaquin Abugattas-Nuñez del Prado, Juan R. Martinez-Morales, Michelle DeVore, Javier R. Guelfo, Emry O. Brannan, Wei Wang, Timothy J. Corbin, Andrea M. Moran, Alejandro Sánchez Alvarado, Edward Málaga-Trillo, Carter M. Takacs, Ariel A. Bazzini, Miguel A. Moreno-Mateos

 

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing
Benedetta Artegiani, Delilah Hendriks, Joep Beumer, Rutger Kok, Xuan Zheng, Indi Joore, Susana Chuva de Sousa Lopes, Jeroen van Zon, Sander Tans, Hans Clevers

 

Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes
Carlee MacPherson Cunningham, Gianfranco Bellipanni, Raymond Habas, Darius Balciunas

 

 

HySyn: A genetically-encoded synthetic synapse to rewire neural circuits in vivo
Josh D. Hawk, Daniel A. Colón-Ramos

 

A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and their Differentiated Derivatives
Danny El-Nachef, Kevin Shi, Kevin M. Beussman, Refugio Martinez, Mary C. Regier, Guy W. Everett, Charles E. Murry, Kelly R. Stevens, Jessica E. Young, Nathan J. Sniadecki, Jennifer Davis

 

A Reporter Mouse for In Vivo Detection of DNA Damage in Embryonic Germ Cells
Jordana C. Bloom, John C. Schimenti

 

Histone modification dynamics as revealed by a multicolor immunofluorescence-based single-cell analysis
Yoko Hayashi-Takanaka, Yuto Kina, Fumiaki Nakamura, Leontine E. Becking, Yoichi Nakao, Takahiro Nagase, Naohito Nozaki, Hiroshi Kimura

 

Derivation and characterization of chimera-competent eXtra-Embryonic eNdoderm (XEN) cells from pig blastocysts
Chi Park, Young Jeoung, Jun Uh, Kieun Park, Jessica Bridge, Anne Powell, Jie Li, Laramie Pence, Tianbin Liu, Hai-Xi Sun, Ying Gu, Yue Shen, Jun Wu, Juan-Carlos Izpisua Belmonte, Bhanu P. Telugu

 

Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates
Pascal Poc, Vanessa A. Gutzeit, Julia Ast, Joon Lee, Ben J. Jones, Elisa D’Este, Bettina Mathes, David J. Hodson, Joshua Levitz, Johannes Broichhagen

 

Three dimensional parallelized RESOLFT nanoscopy for volumetric live cell imaging
Andreas Bodén, Francesca Pennacchietti, Ilaria Testa

 

Super-Beacons: open-source probes with spontaneous tunable blinking compatible with live-cell super-resolution microscopy
Pedro M. Pereira, Nils Gustafsson, Mark Marsh, Musa M. Mhlanga, Ricardo Henriques

 

A versatile, multi-laser twin-microscope system for light-sheet imaging
Kevin Keomanee-Dizon, Scott E. Fraser, Thai V. Truong

 

Automated screening by 3D light-sheet microscopy with high spatial and temporal resolution reveals mitotic phenotypes
Björn Eismann, Teresa G Krieger, Jürgen Beneke, Ruben Bulkescher, Lukas Adam, Holger Erfle, Carl Herrmann, Roland Eils, Christian Conrad

 

Single-color Fluorescence Lifetime Cross-Correlation Spectroscopy in vivo
M. Štefl, K. Herbst, M. Rübsam, A. Benda, M. Knop

 

Quantifying Tensile Forces at Cell–Cell Junctions with a DNA-based Fluorescent Probe
Bin Zhao, Ningwei Li, Tianfa Xie, Chungwen Liang, Yousef Bagheri, Yubing Sun, Mingxu You

 

The OptoGenBox – a device for long-term optogenetics in C. elegans
Inka Busack, Florian Jordan, Peleg Sapir, Henrik Bringmann

 

AAV Ablates Neurogenesis in the Adult Murine Hippocampus
ST Johnston, SL Parylak, S Kim, N Mac, CK Lim, IS Gallina, CW Bloyd, A Newberry, CD Saavedra, O Novák, JT Gonçalves, FH Gage, M Shtrahman

 

The Developing Human Connectome Project: typical and disrupted perinatal functional connectivity
Michael Eyre, Sean P Fitzgibbon, Judit Ciarrusta, Lucilio Cordero-Grande, Anthony N Price, Tanya Poppe, Andreas Schuh, Emer Hughes, Camilla O’Keeffe, Jakki Brandon, Daniel Cromb, Katy Vecchiato, Jesper Andersson, Eugene P Duff, Serena J Counsell, Stephen M Smith, Daniel Rueckert, Joseph V Hajnal, Tomoki Arichi, Jonathan O’Muircheartaigh, Dafnis Batalle, A David Edwards

 

 

 

 

Research practice & education

Peer review and preprint policies are unclear at most major journals
Thomas Klebel, Stefan Reichmann, Jessica Polka, Gary McDowell, Naomi Penfold, Samantha Hindle, Tony Ross-Hellauer

 

The extent and drivers of gender imbalance in neuroscience reference lists
Jordan D. Dworkin, Kristin A. Linn, Erin G. Teich, Perry Zurn, Russell T. Shinohara, Danielle S. Bassett

 

Rigor and Transparency Index, a new metric of quality for assessing biological and medical science methods
Joe Menke, Martijn Roelandse, Burak Ozyurt, Maryann Martone, Anita Bandrowski

 

High School Science Fair: Positive And Negative Outcomes
Frederick Grinnell, Simon Dalley, Joan Reisch

 

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