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3 year postdoctoral researcher position in stem cells and developmental biology

Posted by , on 18 February 2024

Job type: Postdoctoral researcher

Location: University of Sheffield, UK

Closing Date: 13 March 2024

The Tsakiridis group (School of Biosciences, University of Sheffield, UK; https://www.tsakiridislab.com/) are seeking an independent and motivated postdoctoral Research Associate to work on a 3 year MRC-funded project at the interface of developmental/stem cell biology and disease modelling. The successful applicant will primarily employ human pluripotent stem cell (hPSC) differentiation and genetic engineering to elucidate the nature of human enteric nervous system (ENS) progenitor dynamics and their crosstalk with Schwann cell precursors during ENS development and Hirschsprung disease. This project is a close collaboration with the group of Conor McCann at the UCL Great Ormond Street Institute of Child Health in London.

Applicants must hold a PhD (or be close to completion/have equivalent experience) in a subject related to stem cell/developmental biology. Experience in hPSC culture and neural/neural crest differentiation, immunocytochemistry, flow cytometry and qPCR is required. Good knowledge of CRISPR/Cas9-based gene editing approaches in hPSCs would be advantageous. The successful candidate will be expected to have excellent interpersonal, written and communication skills, and be able to work to a high standard.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience. To apply see: https://www.jobs.ac.uk/job/DFZ318/research-associate

Salary: £37,099 to £39,347 Grade 7, per annum

Closing Date: 13 March 2024

Scientific fields: Development and disease, Early embryogenesis, Stem cells

Model systems: Human, Mouse

Duration: Fixed term

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