PhD position in Developmental Biology – Graba-Saurin Lab, IBDM, Marseille, France
Posted by Delphine Dauga, on 31 August 2023
Location: IBDM, Marseille, France
Closing Date: 31 October 2023
3 year funded PhD position in Developmental Biology in the team Mechanisms of Gene Regulation by Transcription factors: the work will investigate how transcription factor protein sequences influence liquid-liquid phase separation (LLPS), nuclear sub-compartmentalization and gene regulation during development.
Project description
Our team is generally interested in understanding the bases for morphological diversity, a central question in developmental and evolutionary biology.
The PhD fellow will investigate how protein sequences influence liquid-liquid phase separation (LLPS) and nuclear sub-compartmentalization of transcription factors, and how this impacts on gene regulation during development. Hox proteins, key transcription factors, playing major roles in establishing animal body plans, will serve as paradigm for the study.
The research is part of an AMIDEX funded collaborative research program combining the expertise of the team of Y. Graba and A. Saurin at IBDM (Drosophila molecular genetics and developmental biology) and that of S. Longhi at AFMB (study of Intrinsically Disordered Regions (IDRs) and LLPS).
Previous experience in developmental and molecular biology will be appreciated.
To apply, please send a CV and references to Yacine Graba.
Contact
Closing Date: 31 October 2023
Scientific fields: Gene regulation
Model systems: Drosophila
Duration: Fixed term