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Postdoctoral Research Associate endothelial-to-haematopoietic transition, development of HSC, YAP / TAZ mechanosignalling

Posted by , on 29 May 2023

Job type: Postdoctoral Research Associate

Location: Centre for Regenerative Medicine, University of Edinburgh

Closing Date: 12 July 2023

A postdoctoral research associate position is available to work on analysis of mechanisms underlying the endothelial-to-haematopoietic transition (EHT) and generation of haematopoietic stem cells. You will use embryonic aorta-gonad-mesonephros (AGM) cultures and ES cells to explore effects of mechanical cues and signalling microenvironment. The study is built on long-standing expertise of Medvinsky’s group in the area of developmental haematopoiesis ( Micropatterned substrates will be employed to enhance precision and manipulation of culture conditions (collaboration with Dr G. Blin’ group “Quantitative Biology of Pattern Formation”,

You are encouraged to apply if you have expertise in developmental biology, cell signalling, cell culture and imaging. The position is available until 28/02/2026. For enquires, please email Alexander Medvinsky (a.medvinsky{a} including motivation letter and your CV.

Salary: UE07 £36,333 Per Annum (can be higher depending on experience)

Start date: 1 July 2023

Closing Date: 12 July 2023

Scientific fields: Cell fate control and differentiation, Gene regulation, Signalling, Stem cells, Haematopoiesis, Tissue engineering and organoids

Model systems: Mouse, Human

Duration: Fixed term

Minimum qualifications: PhD

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