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Postdoctoral Research Associate endothelial-to-haematopoietic transition, development of HSC, YAP/TAZ mechanosignalling

Posted by , on 29 May 2023

Job type: Postdoctoral Research Associate

Location: Centre for Regenerative Medicine, University of Edinburgh

Closing Date: 26 June 2023

A postdoctoral research associate position is available to work on analysis of mechanisms underlying the endothelial-to-haematopoietic transition (EHT) and generation of haematopoietic stem cells. You will use embryonic aorta-gonad-mesonephros (AGM) cultures and ES cells to explore effects of mechanical cues and signalling microenvironment. The study is built on long-standing expertise of Medvinsky’s group in the area of developmental haematopoiesis (https://www.ed.ac.uk/regenerative-medicine/research/alexander-medvinsky). Micropatterned substrates will be employed to enhance precision and manipulation of culture conditions (collaboration with Dr G. Blin’ group “Quantitative Biology of Pattern Formation”, https://www.ed.ac.uk/regenerative-medicine/research/guillaume-blin).

You are encouraged to apply if you have expertise in developmental biology, cell signalling, cell culture and imaging. The position is available until 28/02/2026. For enquires, please email Alexander Medvinsky (a.medvinsky{a}ed.ac.uk) including motivation letter and your CV.

Salary: UE07 £36,333 Per Annum (can be higher depending on experience)

Start date: 1 July 2023

Closing Date: 26 June 2023

Scientific fields: Cell fate control and differentiation, Gene regulation, Signalling, Stem cells, Haematopoiesis, Tissue engineering and organoids

Model systems: Mouse, Human

Duration: Fixed term

Minimum qualifications: PhD

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