Post-doc in evolutionary and developmental genetics at UPenn

We are seeking a creative and exceptionally motivated candidate to fill a post-doctoral position in the field of evolutionary and developmental genetics.

Research in the Kamberov lab is directed at uncovering the genetic basis of human adaptive traits, with a core focus on the evolution of skin appendages, namely sweat glands and hair follicles. In this pursuit, we utilize a highly interdisciplinary approach that combines mouse and human genetics with developmental biology and evolutionary genomics. The culmination of this research program is to not only enhance the understanding of human evolution but also to apply what we have learned in translational efforts that lead to the improvement of human health and alleviation of disease, particularly in the context of skin and skin appendage regeneration.

Projects include:
-Dissection of molecular pathways underlying skin appendage development and evolution.
-High throughput screening for regulatory elements controlling the specification and patterning of hair follicles and sweat glands.
-Dissection of stem cell populations in the skin and the regeneration of human skin appendages in vitro.
-Discovery and functional modeling of evolutionarily significant human variants using comparative genomics and humanized mouse models.

The position provides an exciting opportunity to work at the interface of basic and translational research in a collaborative and stimulating environment, and gain experience in a diverse set of technical approaches at the cutting edge of evolutionary, developmental and regenerative biology.

A doctorate in biology or related field is required. Applicants with a strong background in developmental biology, genetics, genomics or molecular biology are encouraged to apply. Prior experience with mouse genetics and husbandry is preferred.

Interested candidates should provide: 1) a CV 2) a brief letter detailing your interest in the lab and relevant past research experience 3) contact information for three references who can comment on your research. Application materials and any questions regarding the position should be addressed to Yana Kamberov: yana2@mail.med.upenn.edu

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