Postdoc position to study Mechanisms of neural progenitor specification

A full 3-year ANR funded postdoctoral position is available at the Centre de Biologie Intégrative Toulouse to study mechanisms by which time is translated into a precise developmental sequence in the context of neocortex development. This position is part of the postdoctoral program of CBI Toulouse (http://cbi-toulouse.fr/eng/). Our research focuses on the role of local cell-to-cell communication via Eph:ephrin signaling in the specification of neural progenitors in the mouse. The specific aim of the proposed project is to identify the cellular and molecular mechanisms linking Eph:ephrin signaling to neural progenitor fate decisions, concentrating on the transcriptional response elicited downstream of Eph activation in neural progenitors.

The project includes genome-wide gene expression analyses (RNA-Seq and ChIP-Seq) to fully characterize the repertoire of genes downstream of Eph:ephrin signaling in cultured progenitors and the assessment of candidate genes in regulating the production of projection neurons in vitro and in vivo. The succesful candidate should have a PhD and a strong background in genome-wide gene expression analyses. Expertise in cell culture and/or mouse genetics would be a plus. The position is available from october 2016.

Highly motivated candidates should send a brief description of their research interests and career goals, their CV, and contact information for three references to Alice Davy (alice.davyatuniv-tlse3.fr)

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