Postdoctoral fellowship in “Transcriptional States of Oligodendrocyte lineage cells in myelination in Development and Multiple Sclerosis”

Applications are invited for a post-doctoral fellow position (scholarship) in Gonçalo Castelo-Branco´s group, Karolinska Institutet, Stockholm, Sweden (http://ki.se/en/mbb/goncalo-castelo-branco-group) Our research group is interested in the molecular mechanisms defining the epigenetic state of cells of the oligodendrocyte lineage, using transcriptomic and epigenomic approaches ((including single-cell technologies). We are particularly focused on how interplay between transcription factors, non-coding RNAs and chromatin modifying enzymes contributes to the transition between epigenetic states in oligodendrocyte precursor cells, with the aim to design epigenetic based-therapies to induce regeneration (remyelination) in demyelinating diseases, such as multiple sclerosis (please refer to our publications in Neurobiology of Disease 2014, Science 2016).
The applicant must have a strong background in oligodendrocyte/myelin biology, in particular with oligodendrocyte precursor cell culture, FACS sorting, immunohistochemistry/FISH and in vivo work (experience with development biology and/or rodent models of disease such EAE or other demyelination models will be particularly valued). Applicants should hold a doctoral degree or expect to defend in 2016 or early 2017. For more information please visit: https://ki.mynetworkglobal.com/en/what:job/jobID:120966/where:4/

Closing date: 2016-12-15
Gonçalo Castelo-Branco, Associate Professor
Laboratory of Molecular Neurobiology
Department of Medical Biochemistry and Biophysics
Karolinska Institutet
Scheeles väg 1,17177 Stockholm, Sweden

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