A Wellcome Trust funded Postdoctoral Research Associate position is available in the lab of Dr. Matt Towers at the University of Sheffield, UK, to work on vertebrate limb development. How embryonic development is timed and scaled remains enigmatic. Understanding the underlying mechanisms remains a central challenge in biology, since these mechanisms coordinate the growth and patterning of all tissues and organs, and when disrupted are likely to form the basis of many congenital disorders. Our recent work on the embryonic chick wing demonstrates a pivotal role for intrinsic timers in limb development (Chinnaiya et al, Nat Comms 2014, Saiz-Lopez et al, Nat Comms 2015; Saiz-Lopez et al, Development 2017, Pickering et al, Biorxiv 2018). The aim of this project is to use a combination of classical grafting techniques and modern genomic analyses in chick embryos to understand the molecular mechanisms of how cells measure time in vivo.
Closing date: 23rd May 2018
See https://towerslab.weebly.com/ for more details of our research.