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Postdoctoral Research Fellow in Mammary Stem Cell Biology

Posted by , on 17 June 2020

Closing Date: 15 March 2021

Location:  Highfield Campus
Salary:   £30,942 to £36,914 per annum 
Full Time – Fixed Term until 31/01/2022
Closing Date:  Thursday 25 June 2020
Interview Date:  Wednesday 01 July 2020
Reference:  1266420BJ

A Research Fellow position is available in Dr. Salah Elias laboratory at the School of Biological Science (SoBS) – University of Southampton (UoS), to study the mechanisms of asymmetric cell division during mammary gland development and homeostasis. The position is available until 31/01/2022 in the first instance.

The Project

Our lab focusses on studying the mechanisms that regulate mammary stem cell fate and dynamics in normal development and breast cancer. This exciting project is a collaboration between our group and Dr. Philip Greulich group based at the School of Mathematics at UoS. It will employ combined in vivo lineage tracing, quantitative three-dimensional (3D) high-resolution imaging and next generation sequencing as well as mathematical/computational modelling to identify novel mechanisms that control mitotic spindle orientation in mammary stem cells; and determine how these mechanisms influence cell fate outcomes.

The Successful Candidate

We are looking for a creative, ambitious and skilled Postdoctoral Researcher Scientist willing to challenge an innovative project by adopting a pro-active attitude and an analytical approach, with a strong interest in interdisciplinary collaboration.

You will be responsible for the development of the wet-lab part of the project, which includes experimental design, data collection and interpretation. You are also expected to contribute to new ideas for research projects, develop ideas for writing grant proposals, prepare scientific reports, write up results for publication in international peer-reviewed journals.

You will hold a PhD* or equivalent professional qualifications and experience in stem cell and/or developmental biology (or related field). A strong evidence of proficiency in cell biology and quantitative advanced microscopy in vivo is necessary. Experience in Next Generation Sequencing is desirable.

The Environment 

There is a strong interdisciplinary research focus at SoBS bringing together researchers from Biological and Medical Sciences, Computer Sciences, Physics and Mathematical Sciences with experimental work housed in a £45 million building that encompasses cutting-edge research infrastructures. You will have full access to all resources and undertake appropriate training in the use of the equipment of our state-of-the-art core facilities to accomplish your studies. You will thrive within a unique international, stimulating and challenging environment.

For informal enquiries, please contact Dr Salah Elias S.K.Elias@soton.ac.uk and/or Dr. Philip Greulich P.S.Greulich@soton.ac.uk

Given COVID-19 outbreak, virtual interviews will be held using Microsoft Teams or Skype.

Equal Opportunities

SoBS holds an Athena SWAN Silver Award, demonstrating commitment to equal opportunities and gender balance in the workplace.

Application Procedure

You should submit your completed application form online at www.jobs.soton.ac.uk. Please include (1) a cover letter outlining your scientific interests, describing how you meet the requirements of the position, and an outline of future goals; (2) a curriculum vitae, (3) contact information for at least two references.

If you need any assistance, please contact Hannah Farrance (Recruitment Team) on recruitment@southampton.ac.uk . Please quote vacancy reference number 1266420BJ on all correspondence.

*Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

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