Pregenerate GmbH is hiring an Imaging Specialist and a Research technician in Vienna
Posted by Johanna, on 4 August 2020
Closing Date: 15 March 2021
Pregenerate GmbH is hiring in Vienna
#Biotechnology #Imaging #Arthritis research # Drug discovery # Vienna # Machine learning #Cell differentiation assay #Organ-on-a-chip #Biotechnology #Microfluidic #EVOS7000 #personalized medicine #Automation #Liquid Handling #cell biology #Molecularbiology
Pregenerate is a young startup based on the lively Vienna Biocenter Campus surrounded by 12 other start up companies. At Pregenerate we are revolutionizing arthritis treatment with our organ-on-a-chip platform. This technology will ultimately allow us to stratify patients into targeted treatment subgroups, and even to tell each clinical patient what the best treatment is for their specific arthritis needs directly. Our device is also poised to save pharmaceutical companies billions of dollars and improve the success rates of their drugs to market, partly because we can use human cells to replace animal testing in pharmaceutical research for arthritis treatments.
Relevant publications:
Rosser, J. et al. Microfluidic nutrient gradient-based three-dimensional chondrocyte culture-on-a-chip as an in vitro equine arthritis model. Mater Today Bio 4, 100023, doi:10.1016/j.mtbio.2019.100023 (2019).
Vinatier, C. & Guicheux, J. Cartilage tissue engineering: From biomaterials and stem cells to osteoarthritis treatments. Ann Phys Rehabil Med 59, 139-144, doi:10.1016/j.rehab.2016.03.002 (2016).
Haltmayer, E. et al. Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritis. PLoS One 14, e0214709, doi:10.1371/journal.pone.0214709 (2019).
Please send the application with CV, academic record and coverletter to faheem@pregenerate.net
Molecular Biologist – technician
Establishment of Gene expression analysis at Pregenerate. Your aim will be to establish robust pipeline for analyzing responses to various medications to indicate the best treatment for arthritis on an individual patient level. Future work will include automating the system using a liquid handler.
Your talents and abilities:
M. Sc. in Life Sciences
Strong expertise in molecular biology (RNA extraction, qPCRs, Immunohistochemistry,…)
Tissue Culture experience
Skills in Excel and R programming would be advantageous
Good organizational skills
Enthusiasm for personalized medicine
Preferred starting date is 1st September, 2020
Imaging specialist
Leading the development of image analysis section at Pregenerate using Organ-on a chip technology. Your aim will be to establish and automated image analysis system to visualize the response of various medication in a 3D microfluidic system.
Your talents and abilities:
PhD in Life Sciences (M Sc. considered)
Strong expertise in imaging and imaging analysis
Image J programming a significant advantage
Experience with Confocal imaging and EVOS 7000
Image automation experience
Experience with microfluidics would advantageous
Skills in Excel and R programming would be advantageous
Project management
Enthusiasm for personalized medicine
Preferred starting time is September / October 2020
Industry experience is preferred
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