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Displaying posts with the tag: cardiac [Clear Filter]

The people behind the papers – Ding Li and Jianbo Wang

Posted by on November 29th, 2019

This interview, the 72nd in our series, was recently published in Development.  Heart development in mammals is a beautifully complex process. Patterning, proliferation and differentiation are all coordinated with cell movements and tissue morphogenesis (for instance elongation, fusion, folding, looping). However, our knowledge of the molecular regulators of heart development currently outstrips what we know about the[…]

Mechanisms for asymmetric heart morphogenesis: About Nodal and tissue intrinsic forces

Posted by on December 11th, 2013

Although we all appear symmetrical from the outside, the organization of our internal organs and organ structure are highly asymmetric. Proper asymmetric positioning and patterning of our organs is very important for correct function, and loss of this asymmetry during organ formation can lead to a variety of serious congenital diseases.  Our recent study identifies[…]

Proepicardial cells go for a swim: how fluid flows guide epicardial progenitors to the heart

Posted by on September 12th, 2013

The epicardium, the layer of cells covering the myocardium, plays an essential role in heart maturation and formation of the heart valves and coronary vasculature. It derives from the proepicardium (PE), a cluster of cells emerging from the inner lining of the pericardial wall, in which the heart is located. During development, PE cells need[…]

CNIC conference: Cardiovascular Development, Disease and Repair

Posted by on September 10th, 2013

CNIC conference: Cardiovascular Development, Disease and Repair 8-9th November 2013 Centro Nacional de Investigaciones Cardiovasculares CNIC, Madrid, Spain. Abstract submission deadline: 20th October 2013 For more information and registration please visit the following webpage: http://www.cnic-conference.com/     Cardiovascular diseases are the leading cause of death worldwide and their treatment is associated with an enormous economic[…]