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Posted by DMDD, on 15 June 2018
Following our latest data release, the DMDD website (dmdd.org.uk) now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb ...Posted by Patrick Lemaire, on 3 April 2018
The project: Single-cell approaches are revolutionizing developmental biology. We can now trace in time the behavior of each cell in a live developing organism (1). In parallel, single-cell transcriptomics and ...Posted by bedzhov, on 15 December 2017
TheMax-Planck-Institute for Molecular Biomedicine in Muenster, Germany has an opening for a PhD student (position-code 15-2017). The position The position is available in the group of Dr. Ivan Bedzhov that is focused on ...Posted by the Node, on 3 August 2017
A paper published online yesterday in Nature (and ‘leaked’ a week ago by the MIT Technology Review) describes the use of CRISPR in human embryos to correct a mutation that ...Posted by DMDD, on 20 July 2017
A new set of DMDD embryo and placenta data has been released, taking our total dataset to 9.5 million images of around 1300 embryos. DMDD is a primary screen of ...Posted by DMDD, on 21 February 2017
A new paper published in Journal of Anatomy shows that measuring the amount of inter-digital webbing in mouse embryos between 14 and 15 days gestation is the best way to find ...Posted by chris.armit@igmm.ed.ac.uk, on 9 February 2017
A recent publication in Developmental Biology by (Armit et al., 2017) describes how the TRACER dataset can be spatially compared with in situ hybridisation gene expression profiles. The TRACER ...Posted by DMDD, on 1 December 2016
This post originally appeared on Annotations, the DMDD blog. New image and phenotype data for embryos and placentas from embryonic lethal knockout mouse lines has been made ...Posted by DMDD, on 4 October 2016
This post first appeared on Annotations, the DMDD blog (blog.dmdd.org.uk). Around a third of targeted gene knockouts in mice are embryonic-lethal. But not all deaths occur during gestation – a ...Posted by DMDD, on 29 September 2016
This article was originally posted on the DMDD website dmdd.org.uk Knowing the ‘normal’ expression of genes during embryo development is key to understanding the differences that occur due to genetic ...