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Basement membrane mechanical properties

Posted by , on 20 May 2022

Extrinsic forces have an underestimated impact on shaping tissues and organs. Extracellular matrixes surround tissues and provide the cells with mechanical stimuli to drive morphogenetic processes.  A specialized extracellular matrix ...
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Stem cell makes its own niche: the story behind the paper

Posted by , on 7 July 2018

In our recent paper published in Nature, we unravel a new mechanism of an extracellular matrix protein secreted by muscle satellite (stem) cells, thereby playing the unusual role of acting ...
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How mechanical signals orchestrate stem cell fate

Posted by , on 23 August 2016

Controlling differentiation using biophysical cues from development Embryonic stem cells have the potential to become any cell type in the adult organism, but coaxing them to a specific fate continues ...
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