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Multiple stem cells, population asymmetry and position-dependent heterogeneity emerge as common features of a niche for Drosophila Follicle Stem Cells and mammalian Intestinal Stem Cells

Posted by , on 16 June 2017

A discussion of “Alternative direct stem cell derivatives defined by stem cell location and graded Wnt signalling,” Nat Cell Biol, 2017. 19(5): p. 433-444.   We have recently revised the model ...

Visualizing stem cells at home

Posted by , on 13 June 2011

The Drosophila ovary is stunningly beautiful, and a playground of wonderful biological questions.  Within the germarium alone, developmental biologists can look at asymmetric division, stem cells and their niches, cell ...

In Development this week (Vol. 138, Issue 2)

Posted by , on 21 December 2010

Boning up on stem cell Igf2-P2 function The insulin-like growth factor (IGF)/insulin signalling pathway regulates cell proliferation, differentiation, aging and life span. During embryonic development, transcription of the mouse and ...

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