the community site for and by developmental biologists

The future of human reproduction: Stepping back from visions of Gattaca

Posted by on January 16th, 2018

The impact of developmental biology on society is particularly acute when it comes to reproduction – research informs efforts to assist reproduction and understand what happens when pregnancy goes wrong. Recent developments in stem cells, culturing conditions, gene editing and sequencing are also revealing aspects of human embryonic development previously hidden from us. Here at[…]

In Development this week (Vol 145, Issue 1)

Posted by on January 16th, 2018

The first Development issue of the year is now complete! Here are the highlights:   RESEARCH HIGHLIGHTS:   Micro-lenses focus on cataract development Cataracts have many potential risk factors but the molecular mechanisms underlying their development are unclear. Aggregates of lens epithelial cells (LECs) derived from human pluripotent stem cells (hPSCs) are a potentially powerful in[…]

Postdoctoral Position – Imaging of adhesion dynamics and in vivo probing of tissue mechanics

Posted by on January 16th, 2018

Two postdoctoral positions are open at the Institute of Developmental Biology (IBDM) in Marseille (France) to visualize the dynamics of adhesion complexes and probe the cellular and tissue-level mechanics of developing embryos. Successful candidates will develop a project in the context of an interdisciplinary collaboration between the groups of Thomas Lecuit, a biologist, and Pierre-François Lenne,[…]

Post Doctoral Position on Pancreas Development and Stem Cells

Posted by on January 15th, 2018

Post Doctoral Researcher  German Centre for Diabetes Research Dresden A post-doctoral position is available in the research group of Dr Anthony Gavalas. The group investigates the role of signaling pathways and metabolism in the late stages of endocrine pancreas development, the application of novel signals for the conversion of human pluripotent stem cells into functional[…]

Postdoctoral position in cardiovascular development lab

Posted by on January 13th, 2018

The composition of extracellular microenvironment is dynamically regulated in time and space during embryonic development. Our lab discovered that cell-type specific expression of the extracellular matrix (ECM) protein fibronectin is essential for mammalian embryogenesis and cardiovascular morphogenesis. Furthermore, we found that fibronectin regulates distinct morphogenetic processes in a cell type-specific manner, and functions both in[…]

The Woods Hole Embryology Experience

Posted by on January 12th, 2018

My first listen to Jimi Hendrix’s album, “Are you experienced?” was as a prepubescent kid who still had a Matchbox car collection. It’s hard to describe. A world of magic opened up for me; to the chagrin of my parents, I decided I wanted to be a musician instead of a scientist, and in a[…]

PhD Position – Systems Biology of Mouse Embryonic Stem Cell Spheroids

Posted by on January 11th, 2018

The InPhInit program by La Caixa offers a competitive PhD fellowship to attract international early-stage researchers to the top Spanish research center with the Severo Ochoa / Maria de Maeztu excellence accreditation. We invite talented and motivated students to apply for the InPhInit Caixa Fellowship program to do a PhD at the “Self-Organization of Biological[…]

Shape the leaves

Posted by on January 10th, 2018

Before I started my PhD study, I didn’t notice that leaves have two sides: the adaxial side and the abaxial side. When my supervisor Dr. Yuling Jiao first asked me whether I would like to work on this leaf dorsiventral developmental process, I thought I should try, for my own curiosity.   The leaf dorsiventral[…]

Developmental biology: ‘not a confined, specified discipline’?

Posted by on January 10th, 2018

Catching up after the holidays, I finally got around to reading Scott Gilbert‘s recently published essay in PloS Biology. In case you haven’t seen it yet, the essay proposes that developmental biology is ‘the stem cell of biological disciplines’, and that many other areas of biology – such as cell biology, genetics, immunology, oncology and[…]

The community for regenerative medicine: RegMedNet

Posted by on January 10th, 2018

What happens when you apply developmental biology to patients? Regenerative medicine! Now, here are some more difficult questions: Who owns a cell-based therapy? What is a ‘minimally manipulated’ product, and should they be administered to patients if they haven’t been approved by the FDA? In 2015, RegMedNet, the network for regenerative medicine, was launched to[…]