the community site for and by developmental biologists

About: IRBBarcelona

Biography:
IRB Barcelona is an independent, non-profit research institution engaged in basic and applied biomedical science that aims to improve quality of life by applying advances in this field. IRB Barcelona was founded in October 2005 by the Government of Catalonia (Generalitat de Catalunya), the University of Barcelona (UB) and the Barcelona Science Park (Parc Científic de Barcelona). The Institute aims to promote multidisciplinary research of excellence at the interface between biology, chemistry and medicine, to foster collaborations with local organisations and international research institutes, to provide high-level training in the biomedical sciences to staff, students and visitors, to promote innovation and technology transfer, and to actively engage in an open dialogue with the public through a series of outreach and education activities. IRB Barcelona is located in the Barcelona Science Park, a centre in which first-class public research converges with the private sector in a stimulating, vanguard scientific environment.
Website:
http://www.irbbarcelona.org/index.php/en

Posts by IRBBarcelona:

The Drosophila fly brings to light the role of morphogens in limb growth

Posted by on July 5th, 2017

• Scientists at IRB Barcelona clarify the function of the genes that drive wing development in the fruit fly Drosophila melanogaster. • Published in the journal eLife, this study unveils that the Dpp morphogen is necessary for wing growth but that its gradient does not govern this process. • Understanding the development of limbs in[…]

Meet Our Scientists VIDEO: Marco Milán: “To study how cells communicate with each other, perhaps the best model organism is the fruit fly”

Posted by on February 15th, 2017

The “Meet Our Scientists” video entitled “Our relative the fly” presents the research performed by Marco Millán on the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, tissue homeostasis, and tumorigenesis.     Marco Milán, ICREA research professor, leads the Development and Growth Control Laboratory at IRB Barcelona. In the[…]

The fly reveals a new signal involved in limb growth

Posted by on January 9th, 2017

Researchers at IRB Barcelona identify a fundamental role of the JAK/STAT signalling pathway in the development and growth regulation of limbs in Drosophila. Published in Nature Communications, the study paves the way to research into the function of this pathway in vertebrate development and its possible involvement in human congenital diseases.   Many of the[…]

Developmental biology offers the key to finding solutions for paediatric cancer, metastasis, and regeneration

Posted by on October 3rd, 2016

From today and until Wednesday, 150 scientists from around the world will debate plasticity and cell migration in the new gathering in the Barcelona Biomed Conference Series, organised by IRB Barcelona and the BBVA Foundation. The 18th conference in this series brings together biologists devoted to the study of development in animal models, specialists in[…]

Research into fly development provides insights into blood vessel formation

Posted by on September 29th, 2016

Researchers working with flies at IRB Barcelona describe that the concentration of some small intracellular organelles determines the branching capacity of tracheal cells.   Tracheal cells are analogous to the cells that form blood vessels in the human body. The inhibition or stimulation of new blood vessels has implications in cancer and in tissue regeneration.[…]

Gene regulation, evolution and the exploitation of new habitats

Posted by on September 21st, 2016

Changes in body organ morphology have allowed animals to better exploit diverse habitats. As organ morphology is under genetic control, genetic modifications provide the basis for the wide range of morphologies. However, as our knowledge of the genetic basis of phenotypic diversification in evolution has focused mostly on quantitative traits, it is not clear how[…]

Researchers dig up new molecular details on “the other type” of stem cells

Posted by on March 11th, 2016

Scientists at IRB Barcelona and CSIC reveal that the combination of two molecular signals determines which cells that have already differentiated can regain their stem cell properties. Their studies on fruit flies allow for advancements in the field of regenerative medicine and a better understanding of processes involved in cancer. In a study published this[…]

Identification of a mechanism by which cells interact with their milieu

Posted by on February 23rd, 2016

Researchers at IRB Barcelona and CSIC discover a mechanism through which the cells of an organism interact with their extracellular matrix   The cells of an organism interact not only with each other but with the extracellular matrix that surrounds them. Increasing evidence is unveiling the relevance of this structure—which is secreted by the cells[…]

Scientists shed light on how cells with an incorrect number of chromosomes lead to tumour development

Posted by on February 9th, 2016

Aneuploid cells—that is to say those with an abnormal number of chromosomes—are found in most human tumours. A study conducted at IRB Barcelona on the fly Drosophila reveals how surviving aneuploid cells favour tumour development.   Barcelona, Thursday 9th February 2016.- A recent analysis of 43,205 human tumours unveiled that 68% of solid tumours are[…]

A technique dating back to 1935 is recovered for cancer research in flies

Posted by on September 15th, 2015

A study conducted by ICREA researcher Cayetano González, at the Institute for Research in Biomedicine (IRB Barcelona), and published in Nature Protocols describes a forgotten technique used in the fly Drosophila melanogaster dating back 80 years. This method allows the transplantation of tissue from larvae to adult flies, thus allowing research into tumour growth and[…]