the community site for and by developmental biologists

About: IRBBarcelona

IRB Barcelona is an independent, non-profit research institution engaged in basic and applied biomedical science that aims to improve quality of life by applying advances in this field. IRB Barcelona was founded in October 2005 by the Government of Catalonia (Generalitat de Catalunya), the University of Barcelona (UB) and the Barcelona Science Park (Parc Científic de Barcelona). The Institute aims to promote multidisciplinary research of excellence at the interface between biology, chemistry and medicine, to foster collaborations with local organisations and international research institutes, to provide high-level training in the biomedical sciences to staff, students and visitors, to promote innovation and technology transfer, and to actively engage in an open dialogue with the public through a series of outreach and education activities. IRB Barcelona is located in the Barcelona Science Park, a centre in which first-class public research converges with the private sector in a stimulating, vanguard scientific environment.

Posts by IRBBarcelona:

Researchers identify a key molecule in flies that adjusts energy use under starvation conditions

Posted by on July 24th, 2014

Marco Milán leads the Development and Growth Control Laboratory (Battista/Minocri, IRB Barcelona)  The Phd student Lara Barrio worked on the role of p53 in metabolism (Battista/Minocri, IRB Barcelona)   Scientists at IRB Barcelona have observed that, when deprived of food, flies that do not express p53 show poor management of energy store. The study, published[…]

A key component of cell division comes to light

Posted by on June 30th, 2014

Jens Lüders leads the Microtubule Organization laboratory (Photo: Battista/Minocri, IRB Barcelona)  “la Caixa” PhD student Nicolas Lecland is the first author of the study published in Nature Cell Biology (Photo: Battista/Minocri, IRB Barcelona) A breakthrough at IRB Barcelona fills a knowledge gap in understanding how the cell division apparatus, the mitotic spindle, is formed. The[…]

The colon has a safety mechanism that restricts tumour formation

Posted by on June 23rd, 2014

When adenomas appear in the colon, the same cells of the tissue produce a molecule that neutralizes its progression. Adenomas, which are highly prevalent in the population, provide the substrate on which carcinomas develop.   Barcelona, Monday 23 June 2014.- Colon cancer development starts with the formation of benign tumours called adenomas. It is estimated[…]

Researchers identify a new suppressor of breast metastasis to the lung

Posted by on May 27th, 2014

The research headed by Roger Gomis at IRB Barcelona, with the collaboration of Joan Massagué, describes that the loss of the suppressor RARRES3 promotes the colonization of breast cancer cells in the lung. RARRES3 could prove to be a useful marker to identify patients with a greater risk of metastasis, as well as providing a[…]

Identified a new possible target to combat muscle wasting

Posted by on April 9th, 2014

The pathological atrophy of skeletal muscle is a serious biomedical problem for which no effective treatment is currently available. Those most affected populations are the elderly diagnosed with sarcopenia and patients with cancer, AIDS, and other infectious diseases that develop cachexia. A study by scientists at the Institute for Research in Biomedicine (IRB), headed by[…]

A study using Drosophila flies reveals new regulatory mechanisms of cell migration

Posted by on March 21st, 2014

A study by Sofia J. Araújo, a Ramón y Cajal researcher with the Morphogenesis in Drosophila lab at the Institute for Research in Biomedicine (IRB), elucidates the genetic regulation of cell migration. Published today in the scientific journal Plos One, the research is part of the thesis work performed by Elisenda Butí, first author of[…]

Scientists unveil a molecular mechanism that controls plant growth and development

Posted by on February 7th, 2014

–  Researchers at IRB and IBMB-CSIC, in Barcelona, and at the University of Wageningen, in the Netherlands, reveal how auxin hormone-regulated proteins activate developmental genes in plants. – Auxins are key components of plant growth and have many applications in agriculture. The biomedical application of these hormones are also being addressed. – The study is[…]

A study on cell migration provides insights into the movement of cancer cells

Posted by on November 20th, 2013

Using Drosophila melanogaster, researchers at IRB Barcelona discover that during multiple cell migrations a single cell can act as leader, dragging the others with it. _____________ The migration of groups of cells in order to form tissues is common during the development of an organism. Discovering how these multiple movements are achieved is not only[…]

Barcelona hosts major European conference on Drosophila research

Posted by on October 14th, 2013

      – On 16-19 October, 700 scientists will meet for the 23 European Drosophila Conference in the Palau de Congressos in Barcelona.       – Drosophila melanogaster, also known as the fruit fly, is a key model organism in genetics and essential for our understanding of disease.       – Jules Hoffmann, French researcher and 2011 Nobel Laureate in Medicine,[…]

Scientists disclose minute-by-minute details of the biological clock of skin stem cells

Posted by on October 14th, 2013

Researchers lead by Salvador Aznar Benitah describe in detail the cyclic activity of the genes in skin stem cells during the course of a day. The correct balance of the biological clock of stem cells affects their function, and its disruption causes aging and can lead to predisposition to skin cancer.   Our skin regenerates[…]