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Displaying posts in the category: Highlights [Clear Filter]

The toilet paper model

Posted by on August 3rd, 2018

  In LM Escudero´s group, we like developmental biology, mathematical biology and computational biology. We try to be imaginative and get inspiration from simple things… such as a toilet paper roll. Using this tool (and some computers), we claim that we have described a novel geometrical shape… You will be wondering… how do you do[…]

July in preprints

Posted by on August 2nd, 2018

Welcome to our monthly trawl for developmental biology (and other related/just plain cool) preprints.    In one of the most contentious (at least on Twitter!) pieces of preprint news in July, Tom Sheldon, Senior Press Manager at the Science Media Center in London, voiced his concerns about the impact of preprints on public understanding of science[…]

C. elegans Development, Cell Biology and Gene Expression and 2018 European Worm Meeting report

Posted by on July 9th, 2018

I recently attended the biennial Development, Cell Biology and Gene Expression C. elegans Meeting, this time in combination with the 2018 European Worm Meeting, in Barcelona. C. elegans meetings are always pretty special, defined more than anything else by the strong sense of community between researchers, or, as well like to call ourselves, ‘Worm People’.[…]

June in preprints

Posted by on July 4th, 2018

Welcome to our monthly trawl for developmental biology (and other related) preprints! This month we found a tranche of preprints getting deep into the mechanics of fly development, a clutch on organoids (retinal, cerebral, cortical!), an investigation into the role of gender in scientific collaboration, and a veritable zoo in our evo-devo section – from[…]

Adult Neurogenesis 2018: Highlights -By Zubair Ahmed Nizamudeen

Posted by on June 29th, 2018

4WH Neurogenesis: What Where Why When and How? Neurogenesis is understood as the process by which neural stem cells (NSCs) produce new neurons. In the adult mammalian brain, this process is known to persist in two restricted locations- the dentate gyrus (DG) region of the hippocampus (see figure below) and the lateral walls of the[…]

Blastoid: the backstory of the formation of blastocyst-like structure solely from stem cells.

Posted by on June 27th, 2018

In our recently published paper1, we showed that mouse stem cells self-organize into blastocyst-like structures, that we termed blastoids. Because blastoids can be generated in large numbers, can be finely manipulated, and implant in utero, they are a powerful tool to investigate the principles of pre- and post-implantation development. Here is the backstory of our[…]

May in preprints

Posted by on June 1st, 2018

Welcome to our monthly trawl for preprints in developmental biology (plus those hopefully relevant for developmental biologists). May featured the usual catch of fascinating and beautiful work across the spectrum in the field, from Hox in mice and beetles, doublesex in beetles and bees, and three spinal cord regeneration preprints (incuding one using lampreys!). Our[…]

From basic questions to exciting findings

Posted by on May 21st, 2018

In this post we report the backstories behind our recently published paper. It was an enjoyable research adventure driven by discussions, readings, exciting experiments and unexpected discoveries. As a result, we described a novel molecular mechanism underpinning stem cell and progenitor maintenance during development. Here is the sequence of the main events that inspired us[…]

April in preprints

Posted by on May 3rd, 2018

Another bumper month for developmental biology and related preprints, this time featuring spiders, lampreys, amphiouxus and plenty of zebrafish, worm and fly research. Also a big month for fans of Sox genes, which turned up in the title of five preprints! My visual highlight is the preprint from David Parichy’s group on zebrafish scale development[…]

First impressions of the BSDB Spring Meeting

Posted by on April 24th, 2018

This year, is the BSDB’s 70th anniversary, and this was clearly reflected at our Spring Meeting, 15-18 April 2018 in Warwick! Apart from an outstanding speaker list, and the award of most BSDB medals & prizes of 2018, we saw a history session which looked back at the past, to then project into the future of[…]