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Evo-chromo: towards an integrative approach of chromatin dynamics across eukaryotes

Posted by on July 18th, 2018

***Deadline to apply for funded ECR places is July 20!***   In November, the Company of Biologists is hosting the latest in its series of Workshops. ‘Evo-chromo’ aims to integrate skills and interests of the fields of chromatin biology and evolutionary biology – if you are an early career researcher and this all sounds appealing[…]

Adult Neurogenesis 2018: Highlights -By Zubair Ahmed Nizamudeen

Posted by on June 29th, 2018

4WH Neurogenesis: What Where Why When and How? Neurogenesis is understood as the process by which neural stem cells (NSCs) produce new neurons. In the adult mammalian brain, this process is known to persist in two restricted locations- the dentate gyrus (DG) region of the hippocampus (see figure below) and the lateral walls of the[…]

From stem cells to human development: Meeting reporter competition winner!

Posted by on June 29th, 2018

In May we ran a competition to find a meeting reporter for Development’s upcoming meeting on human development and stem cells. We had some wonderful entries from across the field, and are delighted today to announce the winner: Antonio Barral Gil, a PhD student in Miguel Manzanares’ Lab at CNIC (The Spanish Center for Cardiac Research) in[…]

Blastoid: the backstory of the formation of blastocyst-like structure solely from stem cells.

Posted by on June 27th, 2018

In our recently published paper1, we showed that mouse stem cells self-organize into blastocyst-like structures, that we termed blastoids. Because blastoids can be generated in large numbers, can be finely manipulated, and implant in utero, they are a powerful tool to investigate the principles of pre- and post-implantation development. Here is the backstory of our[…]

Editorial: Advocating developmental biology

Posted by on June 27th, 2018

This editorial by Aidan Maartens, Andreas Prokop, Katherine Brown and Olivier Pourquié originally appeared in Development   Developmental biology is a discipline with a long and rich history, a vibrant and diverse present, and a future of tremendous potential. The field has had enormous impact beyond its own boundaries, for example providing many key concepts for medical research and[…]

New embryo phenotype data from the DMDD programme

Posted by on June 15th, 2018

Following our latest data release, the DMDD website (dmdd.org.uk) now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb defects and cysts in Col4a2 knockouts and replication of the major features of Meckel syndrome in B9d2 knockouts. We have begun to add immunohistochemistry image[…]

Call for papers: Development at the single cell level

Posted by on June 14th, 2018

Development is pleased to welcome submissions for an upcoming special issue on ‘Development at the single cell level’. This special issue aims to showcase the best research in stem cell and developmental biology, building on the rapidly evolving tools of single cell analysis. The issue will be guest-edited by Allon Klein and Barbara Treutlein, working alongside our team of[…]

Call for new preLighters

Posted by on June 6th, 2018

preLights, The Company of Biologist’s new preprint highlighting service, has now been running for more than three months. At the heart of preLights is the community of early-career researchers who select and highlight interesting preprints in various fields.     We are now ready to grow our team of preLighters and are seeking early-career researchers,[…]

DanStem embarks on a strategic partnership with Helmholtz Zentrum München

Posted by on May 23rd, 2018

Translational stem cell research for type 1 diabetes therapy is in prime focus with a new strategic alliance between The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem) and Helmholtz Zentrum München (HMGU). Through the establishment of a strong R&D platform for manufacturing of human pluripotent stem cell-derived pancreatic islet cells for future stem[…]

Richard Gardner is the 2018 BSDB Waddington Medal winner

Posted by on April 16th, 2018

The Waddington Medal is the only national Developmental Biology award in the UK. It honours outstanding research performance as well as services to the subject community. The medal is awarded annually at the BSDB Spring Meeting, where the recipient presents the Waddington Medal Lecture. Here we introduce the 2018 winner Richard Gardner who won the[…]