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Exciting news on neural stem cell niches: stunning research from Fiona Doetsch’s lab

Posted by on August 26th, 2016

http://www.cell.com/cell-stem-cell/fulltext/S1934-5909(16)30163-1 Sense & Sensibility: niche signals regulate neural stem cells in an age-dependent manner paper feature by Thomas Schwarz-Romond Tissue specific stem cell niches provide lifelong support for adult stem cells. The cell-biological dissection of (adult neural) stem cell – niche interactions uncovered unexpected regulatory functions. These new results imply that stem cell niches actively[…]

The Zika Virus and Systematic Screens of Mouse Mutations

Posted by on July 14th, 2016

  This post was originally published on the DMDD blog.     The Zika virus has raised global awareness of birth defects more than at any time in the last 50 years [1]. A recent Nature Editorial explores the opportunities this presents to increase support for vaccination programmes, compulsory fortification of food staples and investment[…]

“People in this country have had enough of experts”

Posted by on July 2nd, 2016

I woke up this morning to a Facebook reminder of where I was 5 years ago. I was in Lille, France, on a 2 month sabbatical at Université Lille 1 from my PhD at the University of Cambridge, UK. It was supported by an EU collaborative grant to promote scientific interaction between member states.  […]

YEN 2016 review

Posted by on June 26th, 2016

My informal review of YEN this year is by necessity a bit rushed but, for what it is, here it is. Most reviews are very short and pithy/jealous and only exist for some of the talks where, for a combination of good and bad reasons, I paid attention (I have tried to make this review[…]

Hello from Aidan!

Posted by on June 14th, 2016

I’m happy to introduce myself as the Node’s new Community Manager, taking up the reins from Cat Vicente, who said goodbye recently, and left this unique site in great shape. I’ve come to the Node from the lab bench, recently as a postdoc with Nick Brown in Cambridge, and before that as PhD student with[…]

Sweetening with a pinch of salt: maximized Cas9 efficiency in zebrafish

Posted by on June 14th, 2016

  Alexa Burger, Mosimann lab, Institute of Molecular Life Sciences, University of Zürich, Switzerland. When I first heard about the “new” genome editing method in early 2013 called CRISPR-Cas9, I thought: “Never ever again will I work with targeted nucleases!” Now it’s mid-2016, we published our approaches to maximize Cas9 effectiveness in zebrafish with Development[…]

Call for Papers: a Special Collection on Neurodegenerative Diseases

Posted by on May 31st, 2016

Disease Models & Mechanisms invites you to submit original research for consideration for an upcoming Special Collection ‘Neurodegeneration: From Models to Mechanisms to Therapies‘. This ongoing collection will focus on mechanistic insights into neurodegenerative diseases using model systems, with an emphasis on key translational advances made in recent years. This collection will be launched with[…]

2 technical and 1 post-doctoral posts in cell biology, molecular endocrinology and skeletal biology, Imperial College London

Posted by on May 24th, 2016

Professors Graham Williams and Duncan Bassett have 3 full-time posts (5 years each) available. One technical post in skeletal biology is funded by the Horizon 2020 grant: Resetting the THYRoid axis for prevention of AGE-related diseases and co-morbidities. One post-doc and one technician post in molecular and cellular biology are funded by the Wellcome Trust:[…]

Reflecting on the student & postdoc events at the BSCB/BSDB Spring Meeting

Posted by on May 23rd, 2016

Last year, the BSDB carried out a student and postdoc survey (see here), and the results clearly highlighted the need for more dedicated program items for young researchers on BSDB conferences. In response, the BSDB student rep Alex Ashcroft, the BSCB postdoc rep Alexis Barr, and the BSDB postdoc rep  Michelle Ware took initiative and[…]

A mouse embryo atlas using HREM data

Posted by on May 23rd, 2016

For the first time, a reference mouse embryo atlas has been created using HREM image data. For other embryo imaging methods such as micro-CT, a reference embryo atlas has previously been shown to be the basis of automated phenotyping (Wong et al, 2014). This new work (a collaboration between the DMDD programme and the Mouse[…]