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The Node is a place to share news about and with the developmental biology community around the world. If this is your first time on the site, check out this introduction to the Node. You can also find out more about us, and sign up to contribute.
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Woods Hole images 2014 round 3- the winner
Posted by the Node on March 2nd, 2015
And the winner of the latest round of images from the Woods Hole embryology course is… the skate embryo! Here are the full results: - SEM of butterfly scale: 93 votes - Drosophila embryos: 37 votes - Skate embryo: 241 votes - Swallowtail wing: 79 votes Many congratulations to Mary Colasanto (University of […]
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The Node survey- the results
Posted by the Node on March 1st, 2015
The Node is almost 5 years old, and it is now time to revise its design and functionalities. To help us with this, during the last month we asked you to fill in a survey and give us your feedback. In total 169 people completed the survey, and many of you left comments and suggestions. Thank […]
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The Node at the Drosophila Meeting
Posted by the Node on February 26th, 2015
The Node is off to its first conference of the year- the Annual Drosophila Research Conference, i.e. the fly meeting! We will be tweeting from Chicago using the hashtag #DROS2015, and you can also expect a meeting report here on the Node. If you are attending the meeting, why not say hello to our community manager Cat? […]
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(Developmental) Biology around the internet- February 2015
Posted by the Node on February 12th, 2015
Here is February’s round-up of some of the interesting content that we spotted around the internet! News & Research: - A new technique called ‘expansion microscopy’ makes tissues swell up in order to observe structures at higher resolution. - Mary Lyon, the mouse geneticist who proposed the theory of X-chromosome inactivation, died last December. Obituaries on […]
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BSDB Conference Grant application deadline extended!
Posted by BritSocDevBiol (BSDB) on February 4th, 2015
Conference Grant applications of BSDB members for the BSDB/BSCB Spring meeting can be submitted until Sunday the 8th of February. Please, note that you will require an abstract and support statement as is explained here.
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Help the Node by completing our survey!
Posted by the Node on January 19th, 2015
The Node was launched almost 5 years ago, and it is now time to revise its design and functionalities. We have created a short survey that will help us gather your feedback. Please take a few minutes to complete it- the Node is here for the community, and we need your input to know how […]
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The Node in York
Posted by the Node on January 14th, 2015
In our first visit of the year will be to York, in the north of England! Our community manager Cat Vicente will be at the department of Biology this Friday (16th of January) to give two talks about careers in publishing and science communication: - 10.30 a.m. - Coffee and Careers session, aimed at PhD students […]
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Want to attend Adult Neurogenesis 2015? Go as the official meeting reporter…
Posted by Abcam Events on January 12th, 2015
Adult Neurogenesis: Evolution, Regulation and Function May 6-8, 2015 - Dresden, Germany Website: http://www.abcam.com/AdultNeurogenesis2015 2015 is the 50th anniversary of Joseph Altman’s landmark discovery of adult neurogenesis. To celebrate, the fourth conference in Abcam’s Adult Neurogenesis meeting series this meeting will put the developmental process of adult neurogenesis and its regulation into the wider context […]
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Get involved with Young Embryologist Network!
Posted by Claire Bromley on January 12th, 2015
Looking for a New Year’s resolution? Get involved with the Young Embryologist Network! Last year, Young Embryologist Network (YEN) seminars took place at Oxford University, Cardiff University and institutions across London with the help of postgrads, postdocs and young PIs… just like you! This year we want to keep growing! We plan to organise YEN […]
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Life’s Blueprint website
Posted by Benny Shilo on January 5th, 2015
Dear Colleagues, I recently published a popular book presenting the concepts of embryonic development (Life’s Blueprint: The science and art of embryo creation) at Yale University Press. In addition to the text, I tried to convey the concepts of embryonic development by presenting pairs of images, where one portrays a biological example and the other […]
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- pancRNAs in early development [IN THIS ISSUE]
- Uncovering neurogenic potential of striatal astrocytes [IN THIS ISSUE]
- Timing degradation to tune development [IN THIS ISSUE]
- Getting to the heart of heart cell identity [IN THIS ISSUE]
- Asymmetric division and fate in the retina [IN THIS ISSUE]
- Neural development and regeneration: it's all in your spinal cord [MEETING REVIEW]
- A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation [REVIEW]
- Auxin-induced degradation dynamics set the pace for lateral root development [RESEARCH REPORT]
- Gene activation-associated long noncoding RNAs function in mouse preimplantation development [RESEARCH ARTICLES]
- A MEIG1/PACRG complex in the manchette is essential for building the sperm flagella [RESEARCH ARTICLES]
- Contributions of Costal 2-Fused interactions to Hedgehog signaling in Drosophila [RESEARCH ARTICLES]
- Late Alk4/5/7 signaling is required for anterior skeletal patterning in sea urchin embryos [RESEARCH ARTICLES]
- Geometric control of ciliated band regulatory states in the sea urchin embryo [RESEARCH ARTICLES]
- The cytoplasmic domain of the gamete membrane fusion protein HAP2 targets the protein to the fusion site in Chlamydomonas and regulates the fusion reaction [RESEARCH ARTICLES]
- Wnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouse [RESEARCH ARTICLES]
- Muscle composition is regulated by a Lox-TGF{beta} feedback loop [RESEARCH ARTICLES]
- Drosophila small heat shock protein CryAB ensures structural integrity of developing muscles, and proper muscle and heart performance [RESEARCH ARTICLES]
- Extramacrochaetae functions in dorsal-ventral patterning of Drosophila imaginal discs [RESEARCH ARTICLES]
- Cell competition in mouse NIH3T3 embryonic fibroblasts is controlled by the activity of Tead family proteins and Myc [Articles of interest in other COB journals]
- miR-145 suppresses embryo-epithelial juxtacrine communication at implantation by modulating maternal IGF1R [Articles of interest in other COB journals]
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- Editorial Board
- Dpp/Gbb signaling is required for normal intestinal regeneration during infection
- Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development
- Diverse ETS transcription factors mediate FGF signaling in the Ciona anterior neural plate
- Insulin-independent role of adiponectin receptor signaling in Drosophila germline stem cell maintenance
- Loss of cftr function leads to pancreatic destruction in larval zebrafish
- Lizard tail regeneration: regulation of two distinct cartilage regions by Indian hedgehog
- Ontogeny of the mouse vocal fold epithelium
- RhoGAP68F controls transport of adhesion proteins in Rab4 endosomes to modulate epithelial morphogenesis of Drosophila leg discs
- Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms
- The heparan sulfate-modifying enzyme glucuronyl C5-epimerase HSE-5 controls Caenorhabditis elegans Q neuroblast polarization during migration
- Loss of function of the yellow-e gene causes dehydration-induced mortality of adult Tribolium castaneum
- Co-expression of the transcription factors CEH-14 and TTX-1 regulates AFD neuron-specific genes gcy-8 and gcy-18 in C. elegans
- The organizer in evolution–gastrulation and organizer gene expression highlight the importance of Brachyury during development of the coral, Acropora millepora
- Phospholipase C and D regulation of Src, calcium release and membrane fusion during Xenopus laevis development
- Claudin-10 is required for relay of left-right patterning cues from Hensen’s node to the lateral plate mesoderm
- More similar than you think: Frog metamorphosis as a Model of Human Perinatal Endocrinology
- Using Xenopus tissue cultures for the study of myasthenia Gravis pathogenesis
- Editorial Board
- Letter from the editor – issue 399/1–1 March 2015
- Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling
- Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland
- A dual epimorphic and compensatory mode of heart regeneration in zebrafish
- p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas
- Mice lacking the transcription factor SHOX2 display impaired cerebellar development and deficits in motor coordination
- Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction
- A diffusible signal derived from hematopoietic cells supports the survival and proliferation of regenerative cells during zebrafish fin fold regeneration
- Differential regenerative capacity of neonatal mouse hearts after cryoinjury
- Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish
- Tie1 is required for lymphatic valve and collecting vessel development
- A requirement for Gch1 and tetrahydrobiopterin in embryonic development
- Sox4 regulates choroid fissure closure by limiting Hedgehog signaling during ocular morphogenesis
- The boule gene is essential for spermatogenesis of haploid insect male
- The requirement of histone modification by PRDM12 and Kdm4a for the development of pre-placodal ectoderm and neural crest in Xenopus
- The cochlear sensory epithelium derives from Wnt responsive cells in the dorsomedial otic cup
- A 190 base pair, TGF-β responsive tooth and fin enhancer is required for stickleback Bmp6 expression
- A genetic interactome of the let-7 microRNA in C. elegans
- Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall
- Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
- Cre recombinase-regulated Endothelin1 transgenic mouse lines: Novel tools for analysis of embryonic and adult disorders
- IFT46 plays an essential role in cilia development
- Integration of comprehensive 3D microCT and signaling analysis reveals differential regulatory mechanisms of craniofacial bone development
- BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints
- The myogenic repressor gene Holes in muscles is a direct transcriptional target of Twist and Tinman in the Drosophila embryonic mesoderm
- BMP-dependent gene repression cascade in Drosophila eggshell patterning
- Bark beetle controls epithelial morphogenesis by septate junction maturation in Drosophila
- An oncologist׳s friend: How Xenopus contributes to cancer research
- Editorial Board
- From classical to current: Analyzing peripheral nervous system and spinal cord lineage and fate
- Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition
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- The yin and yang of kidney development and Wilms' tumors [Reviews]
- A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth [Research Communications]
- Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4 [Research Communications]
- The DREAM complex promotes gene body H2A.Z for target repression [Research Communications]
- Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt [Research Papers]
- A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation [Research Papers]
- Mechanism of siRNA production from repetitive DNA [Research Papers]
- The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses [Research Papers]
- Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation [Research Papers]
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- TSC1 Activates TGF-β-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition
- CENP-A K124 Ubiquitylation Is Required for CENP-A Deposition at the Centromere
- SCML2 Establishes the Male Germline Epigenome through Regulation of Histone H2A Ubiquitination
- Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry
- Mechanical Tension Drives Cell Membrane Fusion
- Nodal Signaling Range Is Regulated by Proprotein Convertase-Mediated Maturation
- Weaning Triggers a Maturation Step of Pancreatic β Cells
- A Dicer-miR-107 Interaction Regulates Biogenesis of Specific miRNAs Crucial for Neurogenesis
- Puzzling Out Neurodevelopment
- The Evolution of Early Neurogenesis
- Neuronal Aggregates: Formation, Clearance, and Spreading
- Genetic Changes Shaping the Human Brain
- Cellular Functions of the Amyloid Precursor Protein from Development to Dementia
- Programmed Cell Death in Neurodevelopment
- Microglia: Multitasking Specialists of the Brain
- Subcellular Patterning: Axonal Domains with Specialized Structure and Function
- Dynamics and Mechanisms of CNS Myelination
- It Takes a Village: Constructing the Neurogenic Niche
- Evolution of Patterning Systems and Circuit Elements for Locomotion
- Neuronal Regeneration from Ependymo-Radial Glial Cells: Cook, Little Pot, Cook!
