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New phenotype dataset available for embryonic-lethal mouse knockouts

Posted by on December 1st, 2016

    This post originally appeared on Annotations, the DMDD blog.   New image and phenotype data for embryos and placentas from embryonic lethal knockout mouse lines has been made available on the DMDD website today. The knockout data includes the ciliary gene Rpgrip1l as well as Atg16l1, a gene encoding a protein that forms[…]

New meeting: Programming and Reprogramming the Brain

Posted by on November 24th, 2016

On April 3-4, 2017 scientists from around Europe will be converging on Munich, Germany for the next meeting in the Abcam Brain meeting series – Programming and Reprogramming the Brain. Organizers, Benedikt Berninger (Johannes Gutenberg University Mainz) and Paola Arlotta (Harvard University) have put together a fantastic line up of speakers (see preliminary program).   This[…]

Two opportunities at The Company of Biologists

Posted by on November 23rd, 2016

  The Company of Biologists is a not-for-profit publishing organisation dedicated to supporting and inspiring the biological community. We currently have two opportunities available in our Cambridge office.   Journal Website Content Manager We are creating an exciting new role to enhance the community content on our journal websites. We publish five important journals that[…]

PhD and postdoc positions in Luschnig Lab to study tricellular junctions

Posted by on November 22nd, 2016

The group of Stefan Luschnig at the Cluster of Excellence “Cells in Motion” (CiM) and the Institute of Neurobiology, University of Münster, invites applications for a PhD student and postdoc position The positions are available from February 2017 for three years. The Luschnig group investigates developmental, cellular, and molecular aspects of epithelial biology using a[…]

A Bioimage Analysis Community Meeting, NEUBIAS2020

Posted by on November 14th, 2016

  Learn and Communicate Bioimage Analysis NEUBIAS2020 conference is a new annual meeting of the BioImage Analysis community. We are very glad to invite you to the first conference in Lisbon (Portugal) on 12-17th of February 2017, hosted and co-organized by the Gulbenkian Institute of Science. The conference aims to promote knowledge- and technological- transfer between all the[…]

Embryogenesis Explained

Posted by on November 8th, 2016

Gordon, N.K. & R. Gordon (2016). Embryogenesis Explained. Singapore, World Scientific Publishing Company. xxiii+759pp., 431 illustrations. http://www.worldscientific.com/worldscibooks/10.1142/8152 https://www.amazon.com/Embryogenesis-Explained-Natalie-K-Gordon/dp/9814350486/ref=mt_hardcover?_encoding=UTF8&me= Here’s the Table of Contents: Chapter 1: How Embryogenesis Began in Evolution Chapter 2: Developmental Anatomy of the Axolotl Chapter 3: Developmental Genetics: A Flying Tour Chapter 4: Epigenetics: Higher Order Gene Control Chapter 5: The Cytoskeleton[…]

Spotlight on Rat: Translational Impact – a new DMM Special Collection

Posted by on October 18th, 2016

Disease Models & Mechanisms is pleased to announce the launch of a new Special Collection named Spotlight on Rat: Translational Impact. The rat is a key model for basic and preclinical studies of physiology, pharmacology, toxicology and neuroscience, underlining its importance in studies of human disease. There are many reasons for its suitability as a[…]

New phenotype screen examines causes of neonatal death

Posted by on October 4th, 2016

This post first appeared on Annotations, the DMDD blog (blog.dmdd.org.uk). Around a third of targeted gene knockouts in mice are embryonic-lethal. But not all deaths occur during gestation – a significant number of gene knockouts result in death at or shortly after the time of birth. Mice from these knockout lines provide a valuable animal[…]

Would peer review work better if reviewers talked to each other? An interview for Retraction Watch

Posted by on September 21st, 2016

As you may have seen, we at Development have recently announced a change to our peer review process, introducing a cross-referee commenting step. This should be in place within the next week or two, and we’re hoping it will help us to make better decisions on papers, and to make the revision process easier for[…]

Gene regulation, evolution and the exploitation of new habitats

Posted by on September 21st, 2016

Changes in body organ morphology have allowed animals to better exploit diverse habitats. As organ morphology is under genetic control, genetic modifications provide the basis for the wide range of morphologies. However, as our knowledge of the genetic basis of phenotypic diversification in evolution has focused mostly on quantitative traits, it is not clear how[…]