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The Node is a place to share news about and with the developmental biology community around the world. If this is your first time on the site, check out this introduction to the Node. You can also find out more about us, and sign up to contribute.
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Travelling Fellowships- deadline approaching!
Posted by NickyLB on April 16th, 2014
Do you need to learn a new technique? Are you planning a collaborative visit? Then The Company of Biologists and Development can help! We offer Travelling Fellowships of up to £2,500 to cover the costs of travel, accommodation, subsistence and visa fees. The next deadline for applications is the 30th of April! Find more information about how […]
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(Developmental) Biology around the internet- April 2014
Posted by the Node on April 13th, 2014
Here is our monthly round-up of some of the interesting content that we spotted around the internet: News & Research: - This year’s Waddington Medal was awarded by the British Society for Developmental Biology to Prof Phil Ingham! - Are you a budding science writer? The Wellcome Trust launched their 2014 Science Writing Competition, and are […]
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Outreach competition- the winners
Posted by the Node on April 10th, 2014
Science outreach often involves using metaphors, where a real life object or situation is used to explain a complex scientific concept. Last December we launched an outreach competition, and we asked the Node readers to submit pairs of images: a photograph of a real life scene and an image of the scientific concept that it helps […]
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Scheduled Node maintenance- 9th of April
Posted by the Node on April 8th, 2014
We will be doing some maintenance work on the Node on Wednesday the 9th of April, and unfortunately there will be no access to the site during that period. You can expect the Node to be down from 7 p.m. (British Summer time) for approximately 4 hours. We are sorry for the disruption, especially for […]
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Dicty World Race – 2014
Posted by dirimia on March 1st, 2014
The first ever World Dicty Race will require cells to navigate a complex microfluidic maze to reach a pool of chemoattractant at the finish line. Diffusion of the chemoattractant will create a spatial gradient to guide cells along the shortest path to the finish line. The challenge is to engineer Dicty or HL60 cells to […]
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the Node at the CSHL conference on Avian Model Systems
Posted by the Node on February 25th, 2014
The Node is on the road again! Next week, from the 5th to the 8th of March, Cold Spring Habor Laboratories will be hosting a conference on Avian Model Systems, and the Node will be there! Are you attending this meeting? Then say hello to Cat, our community manager, who would love to hear your […]
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(Developmental) Biology around the internet- February 2014
Posted by the Node on February 13th, 2014
Here is our monthly round-up of some of the interesting content that we spotted around the internet: News & Research: - A new paper in Nature claims that cellular reprogramming can be achieved by exposing cells to stress. - The winners of the 2014 SDB awards were announced. Richard Harland, Christopher Wylie and Janet Heasman […]
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BSCB/BSDB Early Bird Registration Deadline is Today!
Posted by ac270 on February 7th, 2014
The early bird deadline for the BSCB/BSDB spring meeting registration is today (Friday 7th of Feb). http://www.bscb-bsdb-meetings.co.uk/reg.htm
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Slidecasts and videos from conference on congenital melanocytic nevus
Posted by Heather on February 5th, 2014
Limited time offer! Read on. As a developmental biologist, I have found my calling in applying what I have learned about normal embryogenesis to better understanding the pathophysiology of various human congenital malformations. Often these are rare diseases, and I work closely with patient associations devoted to those conditions and learning to live with […]
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Woods Hole embryology course 2014- last chance to apply
Posted by the Node on February 4th, 2014
Having celebrated its 120th anniversary last year, the Woods Hole embryology course is back in 2014! The course will consist of 6 intense weeks of lectures and laboratory work, from the 7th of June to the 20th of July, and applications are open to graduate students, postdoctoral fellows and senior researchers seeking a broad view […]
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- Hemogenic endothelium flexes some muscle [IN THIS ISSUE]
- Motor efferent axons lead the way [IN THIS ISSUE]
- On growth and gradients [IN THIS ISSUE]
- Developing concepts of wound healing [IN THIS ISSUE]
- miR-8 enables correct synaptogenesis [IN THIS ISSUE]
- Actomyosin networks and tissue morphogenesis [DEVELOPMENT AT A GLANCE]
- Bioengineering approaches to guide stem cell-based organogenesis [REVIEWS]
- Genomic imprinting in development, growth, behavior and stem cells [REVIEWS]
- CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons [RESEARCH REPORT]
- miR-8 controls synapse structure by repression of the actin regulator Enabled [RESEARCH ARTICLES]
- A conserved axon type hierarchy governing peripheral nerve assembly [RESEARCH ARTICLES]
- Growth control by a moving morphogen gradient during Drosophila eye development [RESEARCH ARTICLES]
- Arabidopsis UNHINGED encodes a VPS51 homolog and reveals a role for the GARP complex in leaf shape and vein patterning [RESEARCH ARTICLES]
- A Gli silencer is required for robust repression of gremlin in the vertebrate limb bud [RESEARCH ARTICLES]
- Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D [RESEARCH ARTICLES]
- High-resolution analysis of gene activity during the Xenopus mid-blastula transition [RESEARCH ARTICLES]
- Semaphorin 5B is a repellent cue for sensory afferents projecting into the developing spinal cord [RESEARCH ARTICLES]
- Cadherin 99C regulates apical expansion and cell rearrangement during epithelial tube elongation [RESEARCH ARTICLES]
- Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish [RESEARCH ARTICLES]
- sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis [Articles of interest in other COB journals]
- Cadherin switching during the formation and differentiation of the Drosophila mesoderm - implications for epithelial-to-mesenchymal transitions [Articles of interest in other COB journals]
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- Editorial Board
- Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers
- Hipk promotes photoreceptor differentiation through the repression of Twin of eyeless and Eyeless expression
- Unc45b is essential for early myofibrillogenesis and costamere formation in zebrafish
- Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells
- Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear
- Mesodermal Nkx2.5 is necessary and sufficient for early second heart field development
- Maternal bias and escape from X chromosome imprinting in the midgestation mouse placenta
- Editorial Board
- Do the BEAF insulator proteins regulate genes involved in cell polarity and neoplastic growth?
- Lhx1 is required in Müllerian duct epithelium for uterine development
- A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans
- Cleavage of the Drosophila screw prodomain is critical for a dynamic BMP morphogen gradient in embryogenesis
- Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads
- CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways
- The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis
- Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones
- Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages
- Editorial Board
- Development and evolution of vertebrate cranial placodes
- Setting appropriate boundaries: Fate, patterning and competence at the neural plate border
- Establishing the pre-placodal region and breaking it into placodes with distinct identities
- Neural crest and placode interaction during the development of the cranial sensory system
- Signaling mechanisms controlling cranial placode neurogenesis and delamination
- Sensational placodes: Neurogenesis in the otic and olfactory systems
- The development of lateral line placodes: Taking a broader view
- The evolutionary history of vertebrate cranial placodes – I: Cell type evolution
- The evolutionary history of vertebrate cranial placodes II. Evolution of ectodermal patterning
- Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland
- Resident progenitors, not exogenous migratory cells, generate the majority of visceral mesothelium in organogenesis
- Editorial Board
- Impact
- Why you should publish your papers in Developmental Biology
- SDB 2014 Meeting Announcement
- Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death
- Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis
- Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis
- Epigenetic regulation of oogenesis and germ stem cell maintenance by the Drosophila histone methyltransferase Eggless/dSetDB1
- Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development
- The bristle patterning genes hairy and extramacrochaetae regulate the development of structures required for flight in Diptera
- Retraction notice to “The human placenta is a hematopoietic organ during the embryonic and fetal periods of development” [Dev. Biol. 327 (2009) 24–33]
- Ecdysone differentially regulates metamorphic timing relative to 20-hydroxyecdysone by antagonizing juvenile Hormone in Drosophila melanogaster
- Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney
- Peroxisomal membrane channel Pxmp2 in the mammary fat pad is essential for stromal lipid homeostasis and for development of mammary gland epithelium in mice
- Cell signaling during development of Dictyostelium
- Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear
- Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning
- The PAF1 complex is involved in embryonic epidermal morphogenesis in Caenorhabditis elegans
- Neuroblast lineage identification and lineage-specific Hox gene action during postembryonic development of the subesophageal ganglion in the Drosophila central brain
- miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells
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- Dystrophic muscle environment induces changes in cell plasticity [Perspectives]
- DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos [Reviews]
- The diabetes gene Hhex maintains {delta}-cell differentiation and islet function [Research Communications]
- Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e [Research Communications]
- HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles [Research Papers]
- miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGF{beta} and Wnt signaling [Research Papers]
- ATR checkpoint kinase and CRL1{beta}TRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks [Research Papers]
- Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression [Research Papers]
- Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress [Research Papers]
- Root growth is modulated by differential hormonal sensitivity in neighboring cells [Research Papers]
- Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin [Errata]
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