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3 thoughts on “Oh my, what big feet you have…”

  1. Dear Kim,

    Jerboas look very interesting; do you know at the molecular level what contributes to the extension of their hindlimb ? Is there any mutations (absent in others rodents) that could explain why the hindlimb is so developed compared to the forelimb ?

    Best,
    Alex




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  2. Hi Alex – You’ve hit right on my research interests. I’m currently investigating mechanisms of elongation by taking a comparative approach to mice (nearest relative of the research models). The plan is to identify genes with differential expression patterns/levels in cell types of interest in the developing skeleton and then investigate functional/regulatory changes that have occurred over the course of evolution. To date I’ve spent the bulk of my time establishing the system, but I’m planning to start some deep sequence analysis in the very near future. Cheers!




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