the community site for and by developmental biologists

An interview with Eric Wieschaus

Posted by on May 18th, 2017

I had started to become a little worried when I didn’t see Eric on the opening day of the conference, but it turned out that his plane to Germany had been delayed by the snowstorms blanketing the Eastern seaboard of the US and he made it in the end. Between sessions later on, we found a slightly[…]

A postdoctoral position to study role of Par-3 in E-cadherin recycling and signalling

Posted by on May 17th, 2017

A postdoctoral BBSRC funded position is available to study role of Par-3 in E-cadherin recycling and signalling in the group led by Dr Natalia Bulgakova The focus of the Bulgakova group is on discovering roles and regulation of cell-cell adhesion using Drosophila as a model organism. We have recently discovered that the protein Par-3[…]

The evolution of an axon guidance model: from chemotaxis to haptotaxis

Posted by on May 16th, 2017

The canonical model The publication of Marc Tessier-Lavigne’s seminal Cell papers (1, 2) in 1994 describing the identification of netrin1 (from the Sanskrit word, netr, meaning “one who guides”) was a defining moment in my graduate career. My friends and I talked about those papers for weeks, from the incredible technical feat, the biochemical purification[…]

Our latest research on Hormonal regulation of temporal gene expression in neural stem cells

Posted by on May 16th, 2017 @ elife   (No Ratings Yet) Loading…

In Development this week (Vol. 144, Issue 10)

Posted by on May 16th, 2017

Here are the highlights from the current issue of Development: A new model for lineage segregation Lineage segregation during gastrulation has long been thought to be driven by differential cell adhesion and cortical tension among cells, which would together lead to a differential tissue surface tension (TST) and the spatial segregation of specific cell types.[…]

Postdoctoral position – single-cell transcriptomics of the human embryonic kidney

Posted by on May 16th, 2017

The Semrau lab Our lab is interested in the fundamental molecular mechanisms underlying lineage decision-making in stem cells and in vivo.  We are fascinated by the question how defined and stable cell types are generated by the interplay of signaling inputs and gene regulatory networks. We study this question by precise quantification of the states[…]

Biotagging: Behind the scenes (and beyond)

Posted by on May 16th, 2017

“It finally got accepted!”, fol­­lowed by “It’s finally out!” about a month later. I am certain this ‘finally’ feeling about their paper is very familiar to those well-acquainted with the peer review process, and it was no different for our recently published Resource article. The ‘biotagging paper’, as we call it within the Sauka-Spengler lab,[…]

Two Bioimage Analysis Schools from NEUBIAS

Posted by on May 15th, 2017

NEUBIAS, the Network of European BioImage Analysts (, is delighted to announce two new Training Schools on BioImage Analysis:   Early Career Investigators (life scientists) Facility staff (imaging & analysis staff) The focus of training will be on construction and automation of image analysis workflows, using as examples more than one toolbox and different exercises.[…]

The people behind the papers: Jun-Ho Ha, Hyo-Jun Lee and Chung-Mo Park

Posted by on May 11th, 2017

Our 20th instalment of this series comes from South Korea and features an investigation into the molecular basis of how temperature influences developmental transitions in Arabidopsis seedlings, recently published in Developmental Cell. We caught up with joint first authors Jun-Ho Ha and Hyo-Jun Lee, and their supervisor Chung-Mo Park, Professor in the Department of Chemistry, Seoul National University (SNU), to hear[…]

Postdoctoral Training Fellow in Congenital Heart Defects in Down Syndrome

Posted by on May 11th, 2017

Location:          The Francis Crick Institute, Midland Road, London Contract:          Fixed-term (3 years), Full time Salary:             Competitive with benefits, subject to skills and experience Vacancy ID:      5003   SHORT INTRODUCTION/SUMMARY   We seek a talented and motivated postdoc to join a Research Group led by Victor Tybulewicz at the Francis Crick Institute. The[…]