the community site for and by developmental biologists

Sunday at The EMBO Meeting – (Mis)folding proteins and an entire session on blastocysts!

Posted by on September 12th, 2011

Here’s my brief roundup of day two at The EMBO Meeting. It started with Susan Lindquist‘s excellent talk on how cells react to stress by synthesising lots of new heat-shock proteins, which help proteins to fold properly. Susan discussed Hsp90 in more detail. It’s a highly specific protein chaperone, helping diverse signalling proteins to fold.[…]

The profession that isn’t

Posted by on September 10th, 2011

This post was my contribution to Science is Vital’s latest campaign on science careers. If you haven’t done so yet, I warmly encourage to get involved with the movement. THE PROFESSION THAT ISN’T As I enter the last 6 months of my first postdoc, I am confronted by a number of issues with having chosen[…]

An Informative Career Day at The EMBO Meeting in Vienna

Posted by on September 10th, 2011

What shall I do, and once decided, how can I get my dream job after completing my PhD or postdoc, especially if I don’t want to become a group leader? Questions many of us ask ourselves sooner or later, and there are more options than the pessimistic among us might be able to imagine. These[…]

Satellite cells muscle their way into the stem cell spotlight

Posted by on September 8th, 2011

Researchers have long known about regeneration of injured muscles, and have debated about the exact source of the muscle stem cells that perform this amazing feat.  A group of papers in a recent issue of Development shine a stem cell spotlight on satellite cells. Following injury, skeletal muscles are regenerated by muscle stem cells, but[…]

Optical clearing with Scale

Posted by on September 8th, 2011

Transparency. A desirable virtue in many walks of life, and a particularly useful trait in developmental biology.  Model organisms that are see-through offer unique advantages, especially when it comes to detailed 3D imaging. A new report in Nature Neuroscience offers a potential advance in this area. Researchers from Japan have stumbled upon a novel aqueous[…]

Turtles in a nutshell

Posted by on September 7th, 2011

Turtles are peculiar vertebrates. They have a compact skull with no temporal openings, a beak instead of teeth, a contractible neck, and a shell covering its trunk. The famous turtle shell is composed of two halves, a plastron (ventral) and a carapace (dorsal). The latter is an exquisite arrangement of vertebrae and fan-shaped ribs with[…]

Leaving the lab: career development for developmental biologists

Posted by on September 6th, 2011

Over the past months, we’ve heard from several people who left research for a career away from the bench. Now, a summary of all these posts appears in Development, followed by some tips for graduate students, postdocs, and their supervisors. Below is the full text of the article, but it’s also free on Development, and[…]

In Development this week (Vol. 138, Issue 19)

Posted by on September 6th, 2011

Here are the research highlights form the current issue of Development: Modelling liver development with ES cells: HNF4A is key Human embryonic stem cells (hESCs), via their ability to differentiate into a plethora of cell types, offer an attractive approach for regenerative medicine, but they also offer a means of studying cell differentiation, and hence[…]

Group Leader position available at MRC-NIMR London

Posted by on September 4th, 2011

Applications are invited for a Principal Investigator position to lead a new research group in Cell and Developmental Biology. We are particularly interested in candidates using quantitative approaches to study any aspect of the cellular and molecular dynamics of developing tissues. Candidates should have an outstanding track record and an ability to lead a team[…]

Node updates

Posted by on August 31st, 2011

Survey As you know we carried out a survey about the Node this summer. Thank you to those who answered our questions! It was very helpful. We’re currently analysing the results, and you can expect a report on the Node soon. One lucky survey participant, Greg Shanower of The Commonwealth Medical College in Scranton, Philadelphia[…]