Axon guidance relies on the reception and integration of molecular cues from the environment by growth cones, and defective pathfinding results in misplaced projection patterns in the mature nervous system. A new paper in Development investigates this process in the Drosophila neuromucular system, as well as the consequences of axonal miswiring to locomotion. We caught up[…]
Applications are invited from highly motivated individuals dedicated to peruse a PhD and who are interested in nerve/tumour interactions and nervous system development. PROJECT DESCRIPTION During tumour progression nerves and tumours interact resulting in tumour cells using nerves as a metastatic route out of the organ, through a process called perineural invasion (PNI). While this[…]
Applications are invited from highly motivated individuals who are interested in fundamental mechanisms of neuronal migration and axon guidance. The main focus of our research is to understand the molecular and cellular mechanisms underlying the development of neural circuits using the embryonic spinal cord as a model system (http://www.ucmm.umu.se/english/research/sara-wilson/). The fellowship is funded for two[…]
It’s all about the wires. But what about the glue? Networks make us who we are. I am not talking about social networks but about neural networks that define how we perceive the world and how we act. For a century, neuroscientists have sought to understand functions of neural networks in condition and how such[…]
This article was first published in the BSDB Summer newsletter The Autumn Meeting of the BSDB on ‘Axon Guidance and Regeneration’, held on the 28th – 30th August, 2013 at the University of Aberdeen in the beautiful surroundings of Old Aberdeen, was an excellent conference of around sixty delegates, full of exciting talks, highly[…]
Cold Spring Harbor axon guidance, synaptic plasticity and regeneration conference meeting report. Great weather, loads of interesting science and plenty of drunken dancing…what more could you want from a conference.