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New embryo phenotype data from the DMDD programme

Posted by , on 15 June 2018

Following our latest data release, the DMDD website (dmdd.org.uk) now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb ...
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PhD position: Single-cell elucidation of the evolution of an embryonic transcriptional programme

Posted by , on 3 April 2018

The project: Single-cell approaches are revolutionizing developmental biology. We can now  trace in time the behavior of each cell in a live developing organism (1). In parallel, single-cell transcriptomics and ...
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PhD student position -  Max Planck Institute for Molecular Biomedicine

Posted by , on 15 December 2017

TheMax-Planck-Institute for Molecular Biomedicine in Muenster, Germany has an opening for a PhD student (position-code 15-2017). The position The position is available in the group of Dr. Ivan Bedzhov that is focused on ...
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Reactions to the CRISPR human embryo paper

Posted by , on 3 August 2017

A paper published online yesterday in Nature (and ‘leaked’ a week ago by the MIT Technology Review) describes the use of CRISPR in human embryos to correct a mutation that ...
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9.5 million knockout mouse embryo images now available

Posted by , on 20 July 2017

A new set of DMDD embryo and placenta data has been released, taking our total dataset to 9.5 million images of around 1300 embryos. DMDD is a primary screen of ...
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Why are geneticists measuring the webbing between mouse embryo fingers?

Posted by , on 21 February 2017

A new paper published in Journal of Anatomy shows that measuring the amount of inter-digital webbing in mouse embryos between 14 and 15 days gestation is the best way to find ...
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Transposons in Embryo Space – TRACER maps in EMAGE

Posted by , on 9 February 2017

A recent publication in Developmental Biology by (Armit et al., 2017) describes how the TRACER dataset can be spatially compared with in situ hybridisation gene expression profiles.   The TRACER ...
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New phenotype dataset available for embryonic-lethal mouse knockouts

Posted by , on 1 December 2016

    This post originally appeared on Annotations, the DMDD blog.   New image and phenotype data for embryos and placentas from embryonic lethal knockout mouse lines has been made ...
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New phenotype screen examines causes of neonatal death

Posted by , on 4 October 2016

This post first appeared on Annotations, the DMDD blog (blog.dmdd.org.uk). Around a third of targeted gene knockouts in mice are embryonic-lethal. But not all deaths occur during gestation – a ...
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New data reveals gene expression during mouse embryo development

Posted by , on 29 September 2016

This article was originally posted on the DMDD website dmdd.org.uk Knowing the ‘normal’ expression of genes during embryo development is key to understanding the differences that occur due to genetic ...
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