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Displaying posts with the tag: germline [Clear Filter]

Worms teach about germline stem cells

Posted by on October 10th, 2012

To me, the stem cells within a germline are a perfect storm of fascination.  Stem cells are, of course, intriguing in their ability to self-renew and differentiate, and a germline is intriguing in its ability to generate gametes.  Add stem cells and germlines together, and you have amazing biology in front of you…and more biology[…]

Live imaging of stem cell maintenance, loss, and renewal in the Drosophila testis

Posted by on July 28th, 2011

Stem cells have often been imaged live in culture, but very few stem cell systems are conducive to live imaging within their native tissues.  An essential property of adult stem cells that they are maintained at specific anatomical locations called niches.  The interactions between stem cells and their niche are crucial, but are often disrupted[…]

In Development this week (Vol. 138, Issue 7)

Posted by on March 8th, 2011

Here are the research highlights from the current issue of Development: A breath of fresh air: miRNAs regulate lung development Throughout development, a proper balance between the proliferation and differentiation of progenitor cells is essential but the gene regulatory networks that control this balance are only partly understood. Here, Edward Morrisey and colleagues report that[…]

In Development this week (Vol. 138, Issue 5)

Posted by on February 8th, 2011

Here are the highlights from the current issue of Development: From pluripotent to pancreatic fates A reliable method for generating insulin-producing β-cells from human pluripotent stem cells (hPSCs) would provide new therapeutic options for people with diabetes. So far, no-one has developed such a method but, on p. 861, Gordon Keller and colleagues provide new[…]