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Displaying posts with the tag: organoid [Clear Filter]

The evolution from mouse to human models of lung development

Posted by on September 4th, 2017

The story behind our eLife paper: Nikolić, M. Z., Caritg, O., Jeng, Q., Johnson, J.-A., Sun, D., Howell, K. J., Brady, J. L., Laresgoiti, U., Allen, G., Butler, R., Zilbauer, M., Giangreco, A., Rawlins E.L. (2017). Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids. Elife[…]

NIH launches competition to develop human eye tissue in a dish

Posted by on June 21st, 2017

3-D Retina Organoid Challenge to spur breakthroughs in treating blinding diseases The National Eye Institute (NEI), part of the National Institutes of Health, has opened the first stage of a federal prize competition designed to generate miniature, lab-grown human retinas. The retina is the light- sensitive tissue in the back of the eye. Over the[…]

Three dimensional human lung tissue in a dish

Posted by on May 6th, 2015

Pioneering efforts by others have made enormous strides in our ability to generate human lung tissue from human pluripotent stem cells (hPSCs); however, these efforts have largely focused on deriving lung-specific cells as flat monolayer cultures or growing these cells on scaffolds 1-7. In our paper, published recently in the open access journal eLife 8,[…]