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Displaying posts with the tag: polarity [Clear Filter]

Forgotten classics: Cut and paste embryology

Posted by on February 2nd, 2017

Hörstadius, S. 1939. The mechanics of sea urchin development, studied by operative methods. Biological Reviews 14(2):132-179. Recommended by Bob Goldstein, University of North Carolina at Chapel Hill   Sven Hörstadius stands alongside the likes of Boveri, Spemann, Mangold and Driesch as a giant of experimental embryology in the first half of the twentieth century. While[…]

From our sister journals- April 2016

Posted by on April 29th, 2016

Here is some developmental biology related content from other journals published by The Company of Biologists.           New neural crest EMT reporter Stewart and colleagues describe a novel neural crest EMT reporter for rapid in vivo drug screening in zebrafish. They use to identify a small-molecule EMT inhibitor that blocks this process by activating retinoic[…]

From our sister journals- March 2016

Posted by on March 18th, 2016

Here is some developmental biology related content from other journals published by The Company of Biologists.           Drosophila as a model to study human disease The latest issue of Disease Models & Mechanisms highlights the translational impact of Drosophila research. In this issue, Moulton and Letsou review several Drosophila models of human inborn errors of[…]

Moving proteins within living embryos using light

Posted by on February 24th, 2016

By Clare Buckley and Rachel Moore One of the things that we find most challenging about working with whole vertebrate organisms is how we can tie ourselves in knots trying to unpick the function of a single component within such an intricate and interconnected web of proteins and signalling cascades. All too often knocking out[…]

An interview with Peter Lawrence

Posted by on January 20th, 2016

This interview first featured in Development.   Peter Lawrence, FRS, is a fly geneticist based at the Department of Zoology at the University of Cambridge. During his illustrious career he has carried out pioneering work on pattern formation and polarity, and his contributions have been recognised by many honours, including the Prince of Asturias prize[…]

Two recent workshops organised by The Company of Biologists

Posted by on July 18th, 2014

As you probably know, The Company of Biologists (the not-for-profit publisher behind the Node and Development) funds a variety of meetings and conferences every year, and since 2010 that it also organises its own series of workshops. The workshops are generally interdisciplinary in nature, aiming to bring together researchers who do not necessarily meet otherwise. The[…]

Electrifying news for embryologists

Posted by on June 17th, 2014

Electroporation: an efficient technique for embryologists During embryonic development, the specification of different cell types giving rise to the future organs involves a precise spatiotemporal regulation of cell proliferation, migration, and differentiation. Studying these processes requires tools to manipulate gene expression locally in the developing embryo.To this aim, embryologists have widely used the technique of[…]

Dicty World Race – 2014

Posted by on March 1st, 2014

The first ever World Dicty Race  will require cells to navigate a complex microfluidic maze to reach a pool of chemoattractant at the finish line.  Diffusion of the chemoattractant will create a spatial gradient to guide cells along the shortest path to the finish line. The challenge is to engineer Dicty or HL60 cells to[…]

In Development this week (Vol. 138, Issue 16)

Posted by on July 26th, 2011

Here are the research highlights from the current issue of Development: Pushing the nuclear envelope Not all nuclei are regular spheres as is often shown in textbooks. For example, in Drosophila embryos, nuclei are initially spherical but they elongate and acquire an irregular lobulated morphology during cellularisation. These morphological changes coincide with transcriptional activation of[…]

Postdoc position – Melbourne Australia

Posted by on June 1st, 2011

Position Available: POST DOCTORAL RESEARCHER With A/Prof Helena Richardson Cell Cycle and Development Lab Peter MacCallum Cancer Centre Melbourne, Victoria Australia Project: Apico-basal polarity regulators, Signalling pathways and Tumourigenesis Available from Sept 2011 – contract initially 1 year with scope for extension   Our lab uses Drosophila as a model of tumour development, and through[…]