the community site for and by developmental biologists

Beyond morphogen signaling

Posted by on June 25th, 2019

By Dörthe Jülich & Scott Holley   Organizers pattern surrounding tissues via secreted morphogens that specify different cell states as a function of concentration. Wolpert’s French Flag model is commonly used to describe how morphogen gradients specify different fates. Our recent study integrates tail organizer signaling with control of morphogenesis during vertebrate body elongation (Das,[…]

The Pros and Cons of having an ELN: What I’ve learned from my time in a wet lab

Posted by on June 24th, 2019

With its growing adoption in the laboratory, an electronic lab notebook, or ELN, can be a useful tool to aid research, whether in academia or industry. But I found there is limited information on the practicalities of an ELN in a wet lab. Wet labs are a messy business, so strict guidelines are put in[…]

The people behind the papers – Amsha Proag and Magali Suzanne

Posted by on June 24th, 2019

This interview, the 65th in our series, was recently published in Development During development, mechanical forces sculpt tissues into myriad forms. Actomyosin contractility generated within the cell has an increasingly appreciated role in this process, but how tissue forces relate to the physical properties of the extracellular matrix is still poorly understood, particularly at longer time scales[…]

Non-zero baselines: the good, the bad, and the ugly

Posted by on June 20th, 2019

Of all the charts being ridiculed at WTFviz, many get shamed for their lack of a zero-baseline. When teaching DataViz, zero-baselines are invariably a topic of debate. The rules about zero baselines are necessary are often unclear. Therefore, let’s quickly recap. Bar charts: always show zero When we ecnode amounts by length, as done in[…]

Genetics Unzipped podcast: Genetics by numbers

Posted by on June 20th, 2019

We’re unravelling the story of the double helix, cracking the triplet code, and sketching out a Punnett square.

Lab Technician in Muscle Development and Regeneration

Posted by on June 19th, 2019

We are looking for a lab technician to assist in research on muscle stem cells, development, regeneration, disease, and evolution. More details about our research can be found at Technician will assist in management of a mouse colony and conduct supervised research (leading to publications). Technician must be reliable, well organized, detail-oriented, excited about[…]

The people behind the papers – Masanori Abe and Reiko Kuroda

Posted by on June 19th, 2019

This interview, the 64th in our series, was recently published in Development One of the most obvious examples of left-right asymmetry in animal bodies comes from snails: in most species or strains, the shells coil dextrally, but some coil sinistrally. The control of coiling is genetic and begins in the early embryo. Previous work has implicated the[…]

Gene Targeting Specialist – Babraham Institute

Posted by on June 18th, 2019

Location: Babraham Institute Starting salary: £36,500 to £45,500 per annum Contract type: Permanent Closing date: 10 July 2019 We are seeking a proactive and highly motivated individual to deliver gene targeting capabilities at the Babraham Institute.  The successful applicant will work closely with scientific staff and will be embedded in the Epigenetics Programme in order to[…]

2 Fully-Funded Postdoc Positions in Regenerative Medicine – deadline extended to August 30

Posted by on June 17th, 2019

Rita Levi-Montalcini Postdoctoral Fellowship in Regenerative Medicine The Center of Regenerative Medicine at Washington University in St. Louis invites applications for the Rita Levi-Montalcini Postdoctoral Fellows in Regenerative Medicine program. These fellowships honor Rita Levi-Montalcini, whose Nobel-winning discovery of Nerve Growth Factor was among the first regenerative biology research to be done at WUSTL. The[…]

Research Assistant/Associate – Bioinformatics (Smith Lab)

Posted by on June 13th, 2019

Department/Location: Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute Salary: £26,243 – £30,395 or £30,395 – £39,609 Reference: PS19502 Closing date: 10 July 2019 The Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate[…]