Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints.

The preprints this month are hosted on bioRxiv – use these links below to get to the section you want:

Developmental biology

• Patterning & signalling
• Morphogenesis & mechanics
• Genes & genomes
• Stem cells, regeneration & disease modelling
• Plant development
• Evo-devo

Cell Biology

Modelling

Reviews

Tools & Resources

Research practice & education

Developmental biology

| Patterning & signalling

Stromal netrin-1 coordinates renal arteriogenesis and mural cell differentiation
Peter M. Luo, Xiaowu Gu, Christopher Chaney, Thomas Carroll, Ondine Cleaver

Oleic acid decouples fecundity and longevity via DAF-12 steroid hormone signaling in C. elegans

Alexandra M. Nichitean, Frances V. Compere, Sarah E. Hall

EOGT Enables Residual Notch Signaling in Mouse Intestinal Cells Lacking POFUT1

Mohd Nauman, Shweta Varshney, Jiahn Choi, Leonard H. Augenlicht, Pamela Stanley

Evolutionarily conserved role of serotonin signaling in regulating actomyosin contractility during morphogenesis

Sanjay Karki, Mehdi Saadaoui, Valentin Dunsing, Elise Da Silva, Jean-Marc Philippe, Cédric Maurange, Thomas Lecuit

Frizzled2 receives the WntA morphogen during butterfly wing pattern formation

Joseph J Hanly, Ling S Loh, Anyi Mazo-Vargas, Teomie S Rivera-Miranda, Luca Livraghi, Amruta Tendolkar, Christopher R Day, Neringa Liutikaite, Emily A Earls, Olaf BWH Corning, Natalie D’Souza, José J Hermina-Perez, Caroline Mehta, Julia Ainsworth, Matteo Rossi, W. Owen McMillan, Michael W Perry, Arnaud Martin

Polycomb safeguards imaginal disc specification through control of the Vestigial-Scalloped complex

Haley E. Brown, Brandon P. Weasner, Bonnie M. Weasner, Justin P. Kumar

An active traveling wave of Eda/NF-kB signaling controls the timing and hexagonal pattern of skin appendages in zebrafish

Maya N. Evanitsky, Stefano Di Talia

Wnt and BMP signalling direct anterior/posterior differentiation in aggregates of mouse embryonic stem cells

Atoosa Amel, Simoné Rossouw, Mubeen Goolam

Juvenile hormones direct primordial germ cell migration to the embryonic gonad

Barton Lacy J, Sanny Justina, Dawson Emily P, Nouzova Marcela, Noriega Fernando Gabriel, Stadtfeld Matthias, Lehmann Ruth

SPATIO-TEMPORAL DYNAMICS OF EARLY SOMITE SEGMENTATION IN THE CHICKEN EMBRYO

Ana Cristina Maia-Fernandes, Ana Martins-Jesus, Tomás Pais-de-Azevedo, Ramiro Magno, Isabel Duarte, Raquel P. Andrade

Identification of overlapping and distinct mural cell populations during early embryonic development

Sarah Colijn, Miku Nambara, Amber N. Stratman

Reuse of an insect wing venation gene-regulatory subnetwork in patterning the eyespot rings of butterflies

Tirtha Das Banerjee, Antónia Monteiro

On growth and form of the mammary gland: Epithelial-mesenchymal interactions in embryonic mammary gland development

Qiang Lan, Ewelina Trela, Riitta Lindström, Jyoti Satta, Mona M. Christensen, Martin Holzenberger, Jukka Jernvall, Marja L. Mikkola

Combined inactivation of RB and Hippo pathways converts differentiating photoreceptors into eye progenitor cells through derepression of homothorax

Alexandra E. Rader, Battuya Bayarmagnai, Maxim V. Frolov

The Role of MAP3K1 in the Development of the Female Reproductive Tract

Eiki Kimura, Maureen Mongan, Bo Xiao, Jingjing Wang, Vinicius S Carreira, Brad Bolon, Xiang Zhang, Katherine A. Burns, Jacek Biesiada, Mario Medvedovic, Alvaro Puga, Ying Xia

Scabrous is distributed via signaling filopodia to modulate Notch response during bristle patterning in Drosophila

Adam Presser, Olivia Freund, Theodora Hassapelis, Ginger L Hunter

Netrin-1 directs vascular patterning and maturity in the developing kidney

Samuel Emery Honeycutt, Pierre-Emmanuel Yoann N’Guetta, Deanna Marie Hardesty, Yubin Xiong, Shamus Luke Cooper, Lori Lynn O’Brien

| Morphogenesis & mechanics

Medioapical contractile pulses coordinated between cells regulate Drosophila eye morphogenesis

 Christian Rosa Birriel, Jacob Malin,  Victor Hatini

Pten, Pi3K and PtdIns(3,4,5)P3 dynamics modulate pulsatile actin branching in Drosophila retina morphogenesis

Jacob Malin, Christian Rosa Birriel, Victor Hatini

Spatial and temporal regulation of Wnt signaling pathway members in the development of butterfly eyespots

Tirtha Das Banerjee, Suriya Narayanan Murugesan, Antόnia Monteiro

DRMY1 promotes robust morphogenesis by sustaining translation of a hormone signaling protein

Shuyao Kong, Mingyuan Zhu, M. Regina Scarpin, David Pan, Longfei Jia, Ryan E. Martinez, Simon Alamos, Batthula Vijaya Lakshmi Vadde, Hernan G. Garcia, Shu-Bing Qian, Jacob O. Brunkard, Adrienne H. K. Roeder

Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.

Moises Freitas-Andrade, Cesar H Comin, Peter C Van Dyken, Julie Ouellette, Joanna Raman-Nair, Nicole Blakeley, Quing Yan Liu, Sonia Leclerc, Youlian Pan, Ziying Liu, Micael Carrier, Karan Thakur, Alexandre Savard, Gareth M Rurak, Marie-Eve Tremblay, Natalina Salmaso, Luciano Da F Costa, Gianfilippo Coppola, Baptiste Lacoste

Transcriptomic profiling of tissue environments critical for post-embryonic patterning and morphogenesis of zebrafish skin

Andrew J Aman, Lauren M Saunders, August A Carr, Sanjay R Srivatsan, Colten Eberhard, Blake Carrington, Dawn E Watkins-Chow, William Pavan, Cole Trapnell, David M. Parichy

Pathways that affect anterior morphogenesis in C. elegans embryos

Balasubramaniam Boopathi, Irini Topalidou, Melissa Kelley, Sarina M. Meadows, Owen Funk, Michael Ailion, David S. Fay

Early embryogenesis in CHDFIDD mouse model reveals facial clefts and altered craniofacial neurogenesis

M Hampl, N Jandova, D Luskova, M Novakova, J Prochazka, J Kohoutek, M Buchtova

Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation

Ailen S. Cervino, Mariano G. Collodel, Ivan A. Lopez, Daniel Hochbaum, Neil A. Hukriede, M. Cecilia Cirio

| Genes & genomes

Single-cell analysis of shared signatures and transcriptional diversity during zebrafish development

Abhinav Sur, Yiqun Wang, Paulina Capar, Gennady Margolin, Jeffrey A. Farrell

Building functional circuits in multispecies brains

Benjamin T. Throesch, Muhammad Khadeesh bin Imtiaz, Rodrigo Muñoz-Castañeda, Masahiro Sakurai, Andrea L. Hartzell, Kiely N. James, Alberto R. Rodriguez, Greg Martin, Giordano Lippi, Sergey Kupriyanov, Zhuhao Wu, Pavel Osten, Juan Carlos Izpisua Belmonte, Jun Wu, Kristin K. Baldwin

Identification of multiple transcription factor genes potentially involved in the development of electrosensory versus mechanosensory lateral line organs

Martin Minařík, Melinda S. Modrell, J. Andrew Gillis, Alexander S. Campbell, Isobel Fuller, Rachel Lyne, Gos Micklem, David Gela, Martin Pšenička, Clare V. H. Baker

FOXL2 interaction with different binding partners regulates the dynamics of granulosa cell differentiation across ovarian development

Roberta Migale, Michelle Neumann, Richard Mitter, Mahmoud-Reza Rafiee, Sophie Wood, Jessica Olsen, Robin Lovell-Badge

Chromatin Reprogramming of In Vitro Fertilized and Somatic Cell Nuclear Transfer Bovine Embryos During Embryonic Genome Activation

Edward J. Grow, Ying Liu, Zhiqiang Fan, Iuri Viotti Perisse, Tayler Patrick, Misha Regouski, Sean Shadle, Irina Polejaeva, Kenneth L. White, Bradley R. Cairns

A single-cell transcriptional timelapse of mouse embryonic development, from gastrula to pup

Chengxiang Qiu, Beth K. Martin, Ian C. Welsh, Riza M. Daza, Truc-Mai Le, Xingfan Huang, Eva K. Nichols, Megan L. Taylor, Olivia Fulton, Diana R. O’Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay Srivatsan, Xinxian Deng, Christine M. Disteche, William Stafford Noble, Nobuhiko Hamazaki, Cecilia B. Moens, David Kimelman, Junyue Cao, Alexander F. Schier, Malte Spielmann, Stephen A. Murray, Cole Trapnell, Jay Shendure

Tracking Early Mammalian Organogenesis – Prediction and Validation of Differentiation Trajectories at Whole Organism Scale

Ivan Imaz-Rosshandler, Christina Rode, Carolina Guibentif, Mai-Linh N. Ton, Parashar Dhapola, Daniel Keitley, Ricard Argelaguet, Fernando J. Calero-Nieto, Jennifer Nichols, John C. Marioni, Marella F.T.R. de Bruijn, Berthold Göttgens

Differentiation trajectories of the Hydra nervous system reveal transcriptional regulators of neuronal fate

Abby S Primack, Jack F Cazet, Hannah Morris Little, Susanne Mühlbauer, Ben D Cox, Charles N David, Jeffrey A Farrell, Celina E Juliano

Single-cell long-read mRNA isoform regulation is pervasive across mammalian brain regions, cell types, and development

Anoushka Joglekar, Wen Hu, Bei Zhang, Oleksandr Narykov, Mark Diekhans, Jennifer Balacco, Lishomwa C Ndhlovu, Teresa A Milner, Olivier Fedrigo, Erich D Jarvis, Gloria Sheynkman, Dmitry Korkin, M. Elizabeth Ross, Hagen U. Tilgner

Transposable Elements are differentially activated in cell lineages during the developing murine submandibular gland

Braulio Valdebenito-Maturana

Multiple repeat regions within mouse DUX recruit chromatin regulators to facilitate an embryonic gene expression program

Christina M. Smith, Edward J. Grow, Sean C. Shadle, Bradley R. Cairns

The Drosophila drop-dead gene is required for eggshell integrity

Tayler D. Sheahan, Amanpreet Grewal, Laura E. Korthauer, Edward M. Blumenthal

Characterization of factors that underlie transcriptional silencing in C. elegans oocytes

Mezmur D. Belew, Emilie Chien, W. Matthew Michael

daf-42 is an evolutionarily young gene essential for dauer development in Caenorhabditis elegans

Daisy S. Lim, Jun Kim, Wonjoo Kim, Nari Kim, Sang-Hee Lee, Daehan Lee, Junho Lee

Spatiotemporal transcriptome atlas of human embryos after gastrulation

Jiexue Pan, Yuejiao Li, Zhongliang Lin, Qing Lan, Huixi Chen, Man Zhai, Shengwei Sui, Gaochen Zhang, Yi Cheng, Yunhui Tang, Qingchen Wang, Ying Zhang, Fuhe Ma, Yue Xu, Yiting Mao, Qinfang Chen, Yichun Guan, Nan Meng, Haiqian Lu, Xiangjuan Li, Tingting Zheng, Xiaoying Yao, Qiuyu Qin, Bin Jiang, Yuxing Ren, Meiqi Luo, Ji Nancuo, Xin Jin, Jianzhong Sheng, Congjian Xu, Xinmei Liu, Yanting Wu, Chenming Xu, Lijian Zhao, Hongbo Yang, Ya Gao, Guolian Ding, Xun Xu, Hefeng Huang

Spatial transcriptome profiling uncovers metabolic regulation of left-right patterning

Hisato Yagi, Cheng Cui, Manush Saydmohammed, George Gabriel, Candice Baker, William Devine, Yijen Wu, Jiuann-huey Lin, Marcus Malek, Abha Bais, Stephen Murray, Bruce Aronow, Michael Tsang, Dennis Kostka, Cecilia W. Lo

Vertical transmission of maternal mitochondrial DNA through extracellular vesicles modulates embryo bioenergetics

David Bolumar, Javier Moncayo-Arlandi, Javier Gonzalez-Fernandez, Ana Ochando, Inmaculada Moreno, Carlos Marin, Antonio Diez, Paula Fabra, Miguel Ángel Checa, Juan José Espinos, David K. Gardner, Carlos Simon, Felipe Vilella

Wnt activity reveals context-specific genetic effects on gene regulation in neural progenitors

Nana Matoba, Brandon D Le, Jordan M Valone, Justin M Wolter, Jessica Mory, Dan Liang, Nil Aygün, K Alaine Broadaway, Marielle L Bond, Karen L Mohlke, Mark J Zylka, Michael I Love, Jason L Stein

A transient dermal niche and dual epidermal programs underlie sweat gland development

Heather L. Dingwall, Reiko R. Tomizawa, Adam Aharoni, Peng Hu, Qi Qiu, Blerina Kokalari, Serenity M. Martinez, Joan C. Donahue, Daniel Aldea, Meryl Mendoza, Ian A. Glass, Birth Defects Research Laboratory (BDRL), Hao Wu, Yana G. Kamberov

| Stem cells, regeneration & disease modelling

Human pluripotent stem cells-derived inner ear organoids recapitulate otic development in vitro

Daniela Doda, Sara Alonso Jimenez, Hubert Rehrauer, Jose F. Carreño, Victoria Valsamides, Stefano Di Santo, Hans Ruedi Widmer, Albert Edge, Heiko Locher, Wouter van der Valk, Jingyuan Zhang, Karl R. Koehler, Marta Roccio

Birth, cell fate and behavior of progenitors at the origin of the cardiac mitral valve

Batoul Farhat, Ignacio Bordeu, Bernd Jagla, Hugo Blanc, Karine Loulier, Benjamin D. Simons, Emmanuel Beaurepaire, Jean Livet, Michel Pucéat

Single Cell Transcriptomics-Informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage

Angela Papalamprou, Victoria Yu, Wensen Jiang, Julia Sheyn, Tina Stefanovic, Angel Chen, Chloe Castaneda, Melissa Chavez, Dmitriy Sheyn

Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network

Debabrata Jana, Priya Singh, Purnima Sailasree, Nithyapriya Kumar, Vijay V Vishnu, Hanuman T Kale, Jyothi Lakshmi, Asha Kumari, Divya Tej Sowpati, P Chandra Shekar

Caenorhabditis elegans models for striated muscle disorders caused by missense variants of human LMNA

Ellen F. Gregory, Shilpi Kalra, Trisha Brock, Gisèle Bonne, G.W. Gant Luxton, Christopher Hopkins, Daniel A. Starr

Overactivated epithelial NF-κB disrupts lung development in human and nitrofen CDH

Florentine Dylong, Jan Riedel, Gaurang M. Amonkar, Nicole Peukert, Paula Lieckfeldt, Katinka Sturm, Benedikt Höxter, Wai Hei Tse, Yuichiro Miyake, Steffi Mayer, Richard Keijzer, Martin Lacher, Xingbin Ai, Jan-Hendrik Gosemann, Richard Wagner

Directed differentiation of human pluripotent stem cells into articular cartilage reveals effects caused by absence of WISP3, the gene responsible for Progressive Pseudorheumatoid Arthropathy of Childhood

Chaochang Li, Mireia Alemany Ribes, Rosanne Raftery, Uzochi Nwoko, Matthew L. Warman, April M. Craft

PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation

Li He, Jiayu Wen, Qi Dai

SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context

Karine Rizzoti, Probir Chakravarty, Daniel Sheridan, Robin Lovell-Badge

Characterization of regeneration initiating cells during Xenopus laevis tail regeneration

Sindelka Radek, Abaffy Pavel, Zucha Daniel, Naraine Ravindra, Kraus Daniel, Netusil Jiri, Smetana Karel Jr., Lukas Lacina, Endaya Berwini Beduya, Neuzil Jiri, Psenicka Martin, Kubista Mikael

Sox11 is enriched in myogenic progenitors but dispensable for development and regeneration of skeletal muscle

Stephanie N. Oprescu, Nick Baumann, Xiyue Chen, Qiang Sun, Yu Zhao, Feng Yue, Huating Wang, Shihuan Kuang

Dedifferentiating germ cells regain stem-cell specific polarity checkpoint prior to niche reentry

Muhammed Burak Bener, Autumn Twillie, Mayu Inaba

p53 promotes revival stem cells in the regenerating intestine after severe radiation injuryv

Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis Verginadis, Andrea R. Daniel, Danielle N. Burner, Lucy M. Driver, Sloane Satow, Stephanie Hasapis, Reem Ghinnagow, Lixia Luo, Yan Ma, Laura D. Attardi, Costas Koumenis, Andy J Minn, Jeffrey L. Wrana, Chang-Lung Lee, David G. Kirsch

Derivation of trophoblast stem cells unveils unrestrained potential of mouse ESCs and epiblast

Debabrata Jana, Purnima Sailasree, Priya Singh, Mansi Srivastava, Vijay V Vishnu, Hanuman T Kale, Jyothi Lakshmi, Gunda Srinivas, Divya Tej Sowpati, P Chandra Shekar

Radical fringe facilitates NOTCH1 and JAG1 cis interactions to sustain Hematopoietic stem cell fate

Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillen, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J. Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluis Espinosa, Anna Bigas

Single-cell analysis reveals distinct fibroblast plasticity during tenocyte regeneration in zebrafish

Arsheen M. Rajan, Nicole L. Rosin, Elodie Labit, Jeff Biernaskie, Shan Liao, Peng Huang

Cell Type-Specific Regulation by a Heptad of Transcription Factors in Human Hematopoietic Stem and Progenitor Cells

Shruthi Subramanian, Julie A.I. Thoms, Yizhou Huang, Paola Cornejo, Forrest C. Koch, Sebastien Jacquelin, Sylvie Shen, Emma Song, Swapna Joshi, Chris Brownlee, Petter S. Woll, Diego Chacon Fajardo, Dominik Beck, David J. Curtis, Kenneth Yehson, Vicki Antonenas, Tracey O’ Brien, Annette Trickett, Jason A. Powell, Ian D. Lewis, Stuart M. Pitson, Maher K. Gandhi, Steven W. Lane, Fatemeh Vafaee, Emily S. Wong, Berthold Göttgens, Hamid Alinejad Rokny, Jason W.H Wong, John E. Pimanda

A quantitative characterization of early neuron generation in the developing zebrafish telencephalon

Glòria Casas Gimeno, Ekaterina Dvorianinova, Carla-Sophie Lembke, Emma SC Dijkstra, Hussam Abbas, Yuanyuan Liu, Judith TML Paridaen

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

Atoosa Amel, Mubeen Goolam

| Plant development

Auxin coreceptor IAA17/AXR3 controls cell elongation in Arabidopsis thaliana root by modulation of auxin and gibberellin perception

Monika Kubalová, Karel Müller, Petre Ivanov Dobrev, Annalisa Rizza,  Alexander M. Jones,  Matyáš Fendrych

Arabidopsis NF-YCs interact with CRY2 and PIF4/5 to repress blue light-mediated hypocotyl growth

Wei Wang, Lin Gao, Tianliang Zhao, Jiamei Chen, Ting Chen, Wenxiong Lin

Physcomitrium patens SMXL homologs are PpMAX2-dependent negative regulators of growth

Ambre Guillory, Mauricio Lopez-Obando, Khalissa Bouchenine, Philippe Le Bris, Alain Lécureuil, Jean-Paul Pillot, Vincent Steinmetz, François-Didier Boyer, Catherine Rameau, Alexandre de Saint Germain, Sandrine Bonhomme

Dynamics of organelle DNA segregation in Arabidopsis development and reproduction revealed with tissue-specific heteroplasmy profiling and stochastic modelling

Amanda K Broz, Daniel B Sloan, Iain G Johnston

A transcriptome analysis of OsNAC02 Ko-mutant during vegetative endosperm development

Mei Yan, Guiai Jiao, Gaoneng Shao, Ying Chen, Maodi Zhu, Lingwei Yang, Lihong Xie, Peisong Hu, Shaoqing Tang

Embryo-specific epigenetic mechanisms reconstitute the CHH methylation landscape during Arabidopsis embryogenesis

Ping-Hung Hsieh, Jennifer M. Frost, Yeonhee Choi, Tzung-Fu Hsieh, Daniel Zilberman, Robert L Fischer

Arabidopsis lateral shoots display two distinct phases of growth angle control

Martina De Angelis, Stefan Kepinski

Autophagy in maternal tissues contributes to Arabidopsis thaliana seed development

Ori Erlichman, Shahar Weiss, Maria Abu-Arkia, Moria Ankary Khaner, Yoram Soroka, Weronika Jasinska, Leah Rosental, Yariv Brotman, Tamar Avin-Wittenberg

Functional analysis of Salix purpurea genes support roles for ARR17 and GATA15 as master regulators of sex determination

Brennan Hyden, Dana L. Carper, Paul E. Abraham, Guoliang Yuan, Tao Yao, Leo Baumgart, Yu Zhang, Cindy Chen, Ronan O’Malley, Jin-Gui Chen, Xiaohan Yang, Robert L. Hettich, Gerald A. Tuskan, Lawrence B. Smart

| Evo-devo

Evolution of chemosensory tissues and cells across ecologically diverse Drosophilids

Gwénaëlle Bontonou, Bastien Saint-Leandre, Tane Kafle, Tess Baticle, Afrah Hassan, Juan Antonio Sánchez-Alcañiz, Roman J. Arguello

Size and locomotor ecology have differing effects on the external and internal morphologies of squirrel (Rodentia: Sciuridae) limb bones

Johannah Rickman, Abigail E Burtner, Tate J Linden, Sharlene E Santana, Chris J Law

Cell Biology

Endothelial Nitric Oxide Synthase Regulates Lymphatic Valve Specification By Controlling β – catenin Signaling During Embryogenesis

Drishya Iyer, Diandra Mastrogiacomo, Kunyu Li, Richa Banerjee, Ying Yang, Joshua P. Scallan

Sexually dimorphic dynamics of the microtubule network in medaka (Oryzias latipes) germ cells

Mariko Kikuchi, Miyo Yoshimoto, Tokiro Ishikawa, Yuto Kanda, Kazutoshi Mori, Toshiya Nishimura, Minoru Tanaka

Spatial transcriptome of developmental mouse brain reveals temporal dynamics of gene expressions and heterogeneity of the claustrum

Yuichiro Hara, Takuma Kumamoto, Naoko Yoshizawa-Sugata, Kumiko Hirai, Song Xianghe, Hideya Kawaji, Chiaki Ohtaka-Maruyama

RNAi-mediated regulation of alg-3 and alg-4 coordinates the spermatogenesis developmental program in C. elegans

Cara McCormick, Alicia K. Rogers

Foxp- and Skor-family proteins control differentiation of Purkinje cells from Ptf1a and Neurogenin1-expressing progenitors in zebrafish

Tsubasa Itoh, Mari Uehara, Shinnosuke Yura, Jui Chun Wang, Akiko Nakanishi, Takashi Shimizu, Masahiko Hibi

Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development

Juliane Tschuck, Vidya Padmanabhan Nair, Ana Galhoz, Gabriele Ciceri, Ina Rothenaigner, Jason Tchieu, Hin-Man Tai, Brent R. Stockwell, Lorenz Studer, Michael P. Menden, Michelle Vincendeau, Kamyar Hadian

Tristetraprolin promotes survival of mammary progenitor cells by restraining TNFα levels

Stedile Micaela, Lara Montero Angela, García Solá Martín Emilio, Goddio María Victoria, Beckerman Inés, Bogni Emilia, Ayre Marina, Naguila Zaira, Coso Omar, Edith C. Kordon

Kinesin-1 promotes centrosome clustering and nuclear migration in the Drosophila oocyte

Maëlys Loh, Fred Bernard, Antoine Guichet

Spatial consistency of cell growth direction during organ morphogenesis requires CELLULOSE-SYNTHASE INTERACTIVE1

Corentin Mollier, Joanna Skrzydeł, Dorota Borowska-Wykręt, Mateusz Majda, Vincent Bayle, Virginie Battu, Jean-Chrisologue Totozafy, Mateusz Dulski, Antoine Fruleux, Roman Wrzalik, Grégory Mouille, Richard S. Smith, Françoise Monéger, Dorota Kwiatkowska, Arezki Boudaoud

RhoA GEF Mcf2lb regulates rosette integrity during collective cell migration

Hannah M. Olson, Amanda Maxfield, Nicholas L. Calistri, Laura M. Heiser, Alex V. Nechiporuk

Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development

Anna R. Yeh, Gregory J. Hoeprich, Bruce L. Goode, Adam C. Martin

Proteomic Investigation of Neural Stem Cell to Oligodendrocyte Precursor Cell Differentiation Reveals Phosphorylation-Dependent Dclk1 Processing

Robert Hardt, Alireza Dehghani, Carmen Schoor, Markus Gödderz, Nur Cengiz Winter, Shiva Ahmadi, Ramesh Sharma, Karin Schork, Martin Eisenacher, Volkmar Gieselmann, Dominic Winter

Modelling

The time integral of BMP signaling determines fate in a stem cell model for early human development

Seth Teague, Gillian Primavera, Bohan Chen, Emily Freeburne, Hina Khan, Kyoung Jo, Craig Johnson, Idse Heemskerk

insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology

Stanley E. Strawbridge, Agata Kurowski, Elena Corujo-Simon, Alastair N. Fletcher, Jennifer Nichols, Alexander G. Fletcher

Single-cell phenomics reveals behavioural and mechanical heterogeneities underpinning collective migration during mouse anterior patterning

Matthew Stower, Felix Zhou, Holly Hathrell, Jason Yeung, Shifaan Thowfeequ, Jonathan Godwin, Falk Schneider, Christoffer Lagerholm, Marco Fritzsche, Jeyan Thiyagalingam, Xin Lu, Jens Rittscher, Shankar Srinivas

Deciphering the Differential Impact of Thrombopoietin/MPL Signaling on Hematopoietic Stem Cell Function in Bone Marrow and Spleen

Sandy Lee, Huichun Zhan

Time, Space and Single-Cell Resolved Molecular Trajectory of Cell Populations and the Laterality of the Body Plan at Gastrulation

Ran Wang, Xianfa Yang, Jiehui Chen, Lin Zhang, Jonathan A. Griffiths, Guizhong Cui, Yingying Chen, Yun Qian, Guangdun Peng, Jinsong Li, Liantang Wang, John C. Marioni, Patrick P.L. Tam, Naihe Jing

Turing pattern prediction in three-dimensional domains: the role of initial conditions and growth

Soha Ben Tahar, Jose J Muñoz, Sandra J Shefelbine, Ester Comellas

Gap junctions in Turing-type periodic feather pattern formation

Chun-Chih Tseng, Thomas E. Woolley, Ting-Xin Jiang, Ping Wu, Philip K. Maini, Randall B. Widelitz, Cheng-Ming Chuong

Tools & Resources

Optimized husbandry and targeted gene-editing for the cnidarian Nematostella vectensis

João E. Carvalho, Maxence Burtin, Olivier Detournay, Aldine R. Amiel, Eric Röttinger

Universal method for generating knockout mice in multiple genetic backgrounds using zygote electroporation

Tomohiro Tamari, Yoshihisa Ikeda, Kento Morimoto, Keiko Kobayashi, Saori Mizuno-Iijima, Shinya Ayabe, Akihiro Kuno, Seiya Mizuno, Atsushi Yoshiki

A Trisomy 21 Lung Cell Atlas

Soumyaroop Bhattacharya, Caroline Cherry, Gail Deutsch, Birth Defects Research Laboratory (BDRL), Ian A. Glass, Thomas J. Mariani, Denise Al Alam, Soula Danopoulos

A Suite of Mouse Reagents for Studying Amelogenesis

Tomas Wald, Adya Verma, Victoria Cooley, Pauline Marangoni, Oscar Cazares, Amnon Sharir, Evelyn J. Sandoval, David Sung, Hadis Najibi, Tingsheng Yu Drennon, Jeffrey O. Bush, Derk Joester, Ophir D. Klein

An Image-Guided Microfluidic System for Single-Cell Lineage Tracking

Aslan Kamil Mahmut, Fourneaux Camille, Yilmaz Alperen, Stavros Stavrakis, Parmentier Romuald, Paldi Andras, Gonin-Giraud Sandrine, J Andrew deMello, Gandrillon Olivier

A Zika virus protein expression screen in Drosophila to investigate targeted host pathways during development

Nichole Link, J Michael Harnish, Brooke Hull, Shelley Gibson, Miranda Dietze, Uchechukwu E Mgbike, Silvia Medina-Balcazar, Priya S Shah, Shinya Yamamoto

An AI-based segmentation and analysis pipeline for high-field MR monitoring of cerebral organoids

Luca Deininger, Sabine Jung-Klawitter, Petra Richter, Manuel Fischer, Kianush Karimian-Jazi, Michael O. Breckwoldt, Martin Bendszus, Sabine Heiland, Jens Kleesiek, Ralf Mikut, Daniel Hübschmann, Daniel Schwarz

Genetic tools for the study of the mangrove killifish, Kryptolebias marmoratus, an emerging vertebrate model for phenotypic plasticity

Cheng-Yu Li, Helena Boldt, Emily Parent, Jax Ficklin, Althea James, Troy J. Anlage, Lena M. Boyer, Brianna R. Pierce, Kellee Siegfried, Matthew P. Harris, Eric S. Haag

Developmental staging and future research directions of the model marine tubeworm Hydroides elegans

Katherine T. Nesbit, Nicholas J. Shikuma

Research practice & education

Building the Next Generation Workforce: Why We Need Science Policy Training at the Undergraduate Level

Gwendolyn Bogard, Erin Saybolt, Moraima Castro-Faix, Adriana Bankston

Purchases dominate the carbon footprint of research laboratories

Marianne De Paepe, Laurent Jeanneau, Jerôme Mariette, Olivier Aumont, André Estevez-Torres

The landscape of biomedical research

Rita González-Márquez, Luca Schmidt, Benjamin M. Schmidt, Philipp Berens, Dmitry Kobak

Twitter and Mastodon presence of highly-cited scientists

Maximilian Siebert, Leonardo Maria Siena, John P.A. Ioannidis

Self-referencing rates in biological disciplines

Sean M. Cascarina

(No Ratings Yet)
Loading...