Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints.

The preprints this month are hosted on bioRxiv – use these links below to get to the section you want:

Developmental biology

• Patterning & signalling
• Morphogenesis & mechanics
• Genes & genomes
• Stem cells, regeneration & disease modelling
• Plant development
• Environment, evolution and development

Cell Biology

Modelling

Tools & Resources

Research practice and education

Developmental biology

| Patterning & signalling

Notch signaling in the embryonic ectoderm promotes periderm cell fate and represses mineralization of vibrissa hair follicles
Dianzheng Zhao, Yunus Ozekin, Erin Binne, Irene Choi, Aftab Taiyab, Trevor Williams, Hong Li

A Genetic Mechanism Linking Hippo Signaling to Dorsoventral Patterning for Control of Head and Eye Development
Basavanahalli Nunjundaiah Rohith, Neha Gogia, Arushi Rai, Amit Singh, Madhuri Kango-Singh

An APP-centered molecular gateway integrates innate immunity and retinoic acid signaling to drive irreversible metamorphic commitment
Ryohei Furukawa, Mizuki Taguchi, Narufumi Kameya, Keisuke Tanaka, Haruka Sato, Takehiko Itoh, Yuh Shiwa

MEIS1 is Required for Establishing Bergmann Glia–Specific Properties in the Developing Cerebellum
Kentaro Ichijo, Toma Adachi, Tomoo Owa, Minami Mizuno, Kyoka Suyama, Kaiyuan Ji, Koichi Hashizume, Ikuko Hasegawa, Eriko Isogai, Masaki Sone, Yukiko U. Inoue, Ryo Goitsuka, Takuro Nakamura, Takayoshi Inoue, Satoshi Miyashita, Kenji Kondo, Tatsuya Yamasoba, Mikio Hoshino

Cell position is more important than cell shape or age for the acquisition of cell identity in the brown alga Ectocarpus
Denis Saint-Marcoux, Bernard Billoud, Sabine Chenivesse, Carole Duchêne, Aude Le Bail, Jane A. Langdale, Bénédicte Charrier

The Joubert gene TMEM67 is required for the correct establishment of spinal dorsal identities in human organoids
Wiegering, K. Bools, I. Anselme, L. Metayer-Derout, O. Mercey, E. Balissat, Y. Bijek, M. Catala, S. Schneider-Maunoury, A. Stedman

Single-Cell Profiling of the Developing Organ of Corti Identifies Etv4/5/1 as Key Regulators of Pillar Cell Identity
Susumu Sakamoto, Matthew W. Kelley

Coordinated inhibition of SOX9 and cell cycle progression by microRNA-200 restricts sebaceous gland fate specification
Arpan Das, Yuheng C Fu, Haimin Li, Megan A. Wong, Annalina Che, Anumeha Singh, Jimin Han, Glen Bjerke, Dongmei Wang, Rui Yi

Smoothened turnover regulated by Hedgehog signaling in Drosophila
Ryo Hatori, Wanpeng Wang, Thomas B. Kornberg

Lipid-mediated reinforcement of FGF/MAPK signaling enables robust otic placode specification
Stephanie R. Peralta, Natalia Maiorana, Michael L. Piacentino

Evidence of autonomous neural specification for both brain and ventral nerve cord tissue in Annelida
Nicole B. Webster, Johnny A. Davila-Sandoval, Allan M. Carillo-Baltodano, Skyler Duda, B. Duygu Özpolat, Néva P. Meyer

| Morphogenesis & mechanics

Force-dependent stabilization of apical actomyosin by Lmo7 during vertebrate neurulation
Miho Matsuda, Sergei Y. Sokol

Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure
Denisa Jaros Belisova, Ema Grofova, Viacheslav Zemlianski, Zuzana Sumbalova Koledova

A Cell Size-Dependent Competition Between Geometry and Polarity Governs Nuclear and Spindle positioning in Early Embryos
Aude Nommick, Macy Baboch, Celia Municio-Diaz, Jeremy Sallé, Remi Le Borgne, Nicolas Minc

Extrinsic MMPs drive epithelial shape change via basal ECM disassembly in the Drosophila wing disc
Chigusa Hinata, Hirotatsu Nakagawa, Shigeaki Nonaka, Katsuya Nozaki, Yoshikatsu Sato, Shizue Ohsawa

A collagen orientation switch reshapes fin architecture
Rintaro Tanimoto, Kazuhide Miyamoto, Koji Tamura, Shigeru Kondo, Junpei Kuroda

Recognizing dUTPase as a mitotic factor essential for early embryonic development
Nikolett Nagy, Otília Tóth, Eszter Oláh, László Henn, Gergely Attila Rácz, Edit Szabó, György Várady, Fanni Beatrix Vigh, Zita Réka Golács, Martin Urbán, Tímea Pintér, Orsolya Ivett Hoffmann, László Hiripi, Hilde Loge Nilsen, Angéla Békési, Miklós Erdélyi, Elen Gócza, Gergely Róna, Judit Tóth, Beáta G. Vértessy

Planar polarization of endogenous ADIP during Xenopus neurulation
Satheeja Santhi Velayudhan, Keiji Itoh, Chih-Wen Chu, Dominique Alfandari, Sergei Y. Sokol

RNA Polymerase III subunit Polr3a is required for craniofacial cartilage and bone development
Bailey T. Lubash, Roxana Gutierrez, Kade Fink, Colette A. Hopkins, Jessica C. Nelson, Kristin E.N. Watt

Cell-cycle inhibition preserves robust development but rebalances lineages in mouse gastruloids
Maxine Leonardi, Yves Paychère, Felix Naef

Distinct roles of the Lyve1 lineage in heart development
Konstantinos Klaourakis, Karolina Zvonickova, Jacinta Kalisch-Smith, Nicola Smart, Duncan Sparrow, David G. Jackson, Paul R. Riley, Joaquim M. Vieira

Spatial Variation in Cortex Glia Cell Cycle Supports Central Nervous System Organization in Drosophila
Vaishali Yadav, Syona Tiwari, Meenal Meshram, Ramkrishna Mishra, Rakesh Pandey, Richa Arya

| Genes & genomes

IAP retrotransposons contribute to the transcriptional diversity of the murine placenta
Samuele M. Amante, Maria L. Vignola, Cyril Pulver, Tessa M. Bertozzi, Anne C. Ferguson-Smith, Marika Charalambous, Miguel R. Branco

MYRF drives heterochronic miRNAs and LIN-42, and amplifies oscillatory programs for stage transitions
Zhao Wang, Shiqian Shen, Xiaoting Feng, Di Chen, Qian Bian, Yingchuan B. Qi

Yin Yang 1-Dependent PcG Function is Essential for TET2 Expression and Early T cell Development
Yinghua Wang, Sahitya Saka, Xuan Pan

A role for HDAC3 in regulating histone lactylation and maintaining oocyte chromatin architecture and fertility
Inês Simões-Gomes, António Jacinto, Ana Pimenta-Marques

The histone code of love: epigenetics of maturation of gonads in the human blood fluke Schistosoma mansoni
Christoph Grunau, Zhigang Lu, Avril Coghlan, Max Moescheid, Thomas Quack, Cristian Chaparro, Eerik Aunin, Jean-Francois Allienne, Adam Reid, Nancy Holroyd, Matt Berriman, Gilda Padalino, Karl F. Hoffmann, Christoph G. Grevelding, Ronaldo de Carvalho Augusto

Histone H3K9 Methyltransferases Regulate Cortical Growth by Coordinating Heterochromatin Formation and Neural Progenitor Dynamics
Sophie Warren, Chris Hemmerich, Ram Podicheti, José-Manuel Baizabal

A developmental timer coordinates organism-wide microRNA transcription
Peipei Wu, Jing Wang, Brett Pryor, Isabella Valentino, David F. Ritter, Kaiser Loel, Justin Kinney, Sevinc Ercan, Leemor Joshua-Tor, Christopher M. Hammell

Identification of germline chromatin modifying factors that influence zygotic transcription activation in C. elegans
Mariateresa Mazzetto, Paige Adekplor, Valerie Reinke

The SynMuvA lin-15A licenses natural transdifferentiation by antagonizing identity safeguarding mechanisms
Sarah Becker, Marie-Charlotte Morin, Julien Lambert, Shashi Kumar Suman, Francesco Carelli, Alex Appert, Stéphane Roth, Sarah Hoff-Yoessle, Jessica Medina-Sanchez, Manuela Portoso, Stéphanie Le Gras, Julie Ahringer, Sophie Jarriault

Decoding the cell intrinsic and extrinsic roles of PRC2 in early embryogenesis
Chengjie Zhou, Meng Wang, Zhiyuan Chen, Yi Zhang

Endogenous retroviral elements LTR8B and MER65 regulate the PSG9 locus that promotes trophoblast syncytialization Insights into placental evolution and pre-eclampsia pathology
Manvendra Singh, Yuliang Qu, Amit Pande, Julianna Zadora, Florian Herse, Martin Gauster, Xuhui Kong, Rongyan Zheng, Rabia Anwar, Katarina Stevanovic, Ralf Dechend, Marie Cohen, Attila Molvarec, Jichang Wang, Miriam K. Konkel, Bin Zhang, Cedric Feschotte, Gabriela Dveksler, Sandra M. Blois, Laurence D. Hurst, Zsuzsanna Izsvák

Single-cell spatially resolved transcriptomic characterization of the developing mouse cochlea
Philippe Jean, Sabrina Mechaussier, Amrit Singh-Estivalet, Céline Trébeau, Aurore Gaudin, Laura Barrio Cano, Andrea Lelli, Fabienne Wong Jun Tai, Sébastien Megharba, Sandrine Schmutz, Sarra Loulizi, Sophie Novault, David Hardy, Carolina Moraes-Cabe, Milena Hasan, Christine Petit, Raphael Etournay, Nicolas Michalski

A conserved C. elegans zinc finger-homeodomain protein, ZFH-2, continuously required for structural integrity and function of alimentary tract and gonad
Antoine Sussfeld, Berta Vidal, Surojit Sural, Daniel M. Merritt, G. Robert Aguilar, Yasmin Ramadan, Oliver Hobert

let-7 miRNA and lin-46 mRNA are the two essential targets of the LIN28 RNA-binding protein in developmental timing
Jana Brunner, Anca Neagu, Dimos Gaidatzis, Lucas J. Morales Moya, Helge Großhans

Conserved Roles of Sp1 in Zebrafish Development and Early Organogenesis
Ankita Sharma, Sudiksha Mishra, Greg Jude Dsilva, Saurabh J Pradhan, Pavan Dev Govardhan, Sanjeev Galande

An Asynchronous Production Line of Meiotic Prophase I in the Mouse Fetal Ovary
Chang Liu, Ziyi Jin, Gan Liu, Guofeng Feng, Jie Li, Yiwei Wu, Hao Jia, Lin Liu

Aging, dauer, and stature phenotypes are conferred by structure-directed missense mutations in the endogenous AGE-1/phosphatidylinositol 3-kinase catalytic subunit
You Wu, Tam Duong, Neal R. Rasmussen, Kent L. Rossman, David J. Reiner

Mapping of CELF1-RNA interactions reveals post-transcriptional control of lens development
Justine Viet, Matthieu Duot, Agnès Méreau, Yann Audic, Iwan Jan, David Reboutier, Catherine Le Goff-Gaillard, Sarah Y Coomson, Salil A Lachke, Carole Gautier-Courteille, Luc Paillard

microRNAs affecting development of body pigmentation in adult Drosophila melanogaster
Abigail M. Lamb, Jennifer A. Kennell, Eden W. McQueen, Evan J. Waldron, Patricia J. Wittkopp

Identification of miR-187 as a modulator of early oogenesis and female fecundity in medaka
Marlène Davilma, Stéphanie Gay, Manon Thomas, Sully Mak, Fabrice Mahé, Laurence Dubreil, Jérôme Montfort, Aurélien Brionne, Julien Bobe, Violette Thermes

Parthenogenote-Derived Brain Unveils the Critical Role of Paternal Genome in Neural Development
Marina Takechi, Yezhang Zhu, Zezhen Lu, Ying Zeng, Ken-Ichi Mizutani, Toru Nakano, Li Shen, Shinpei Yamaguchi

A panoramic view of the expression and function of the Doublesex/DMRT gene family in C. elegans
Chen Wang, Yehuda Salzberg, Meital Oren-Suissa, Oliver Hobert

Lamin A/C directs nucleosome-scale chromatin remodeling to define early lineage segregation in mammals
Alice Sherrard, Liangwen Zhong, Caroline Hoppe, Srikar Krishna, Scott Youlten, Curtis W. Boswell, Stephen Cross, Fiona E. Sievers, Goli Ardestani, Denny Sakkas, Liyun Miao, Zachary D. Smith, Berna Sozen, Antonio J. Giraldez

| Stem cells, regeneration & disease modelling

Prenatal corticosteroid exposure disrupts vascular-immune interactions and impairs steroidogenesis in the fetal testis
Satoko Matsuyama, Lauren Hudepohl, Kazuhiro Matsuyama, Shu-Yun Li, Meghana Ginugu, Xiaowei Gu, Matthew J. Kofron, Vikram Ravindra, Tetsuo Shoda, Tony DeFalco

Hyaluronan underlies the emergence of form, fate, and function in human cardioids
Stefan M. Jahnel, Anna Dimitriadi, Julia Kodnar, Vasileios Gerakopoulos, Yajushi Khurana, Maximilian Mayrhauser, Tobias Ilmer, Keisuke Ishihara, Sasha Mendjan

Profibrotic Changes Following Tension Application in a Fetal Lamb Model of Long Gap Esophageal Atresia
Jessica C. Pollack, Nicolas Vinit, Shelley Jain, Rachel Conan, Melanie Bates, Mia Kwechin, Alicia Eubanks, Mike Xie, Amanda Muir, Emily Partridge

Ybx1 Deficiency Causes ROS-Driven IBD-Like Intestinal Inflammation and Postnatal Lethality
Bo Zhu, Lakhansing Pardeshi, Yingying Chen, Xianqing Zhou, Wei Ge

Dynamic Reorganization of Developmental to Adult Genome Topology Controls the Initiation and Stabilization of the Human Muscle Stem Cell State
Matthew A. Romero, Peggie Chien, Chiara Nicoletti, Hanna L. Liliom, Gabriella Cox, Emily Skuratovsky, Kholoud Saleh, Devin Gibbs, Lily Gane, Dieu-Huong Hoang, Luca Caputo, Jimmy Massenet, Débora R. Sobreira, Pier Lorenzo Puri, April D. Pyle

A single cell atlas defines perinatal factors that drive murine bone marrow development
Brian M Dulmovits, Carson Shalaby, Fangfang Song, James Garifallou, Joshua Bertels, Fanxin Long, Christopher S Thom

Aging disrupts tissue homeostasis and constrains blastema-mediated regeneration in the Cladonema medusa
Ren Kanehisa, Hiroko Nakatani, Sho Takatori, Taisuke Tomita, Masayuki Miura, Yu-ichiro Nakajima

Capturing self-renewing multipotent neural crest stem cells from human pluripotent stem cells
Yayoi Toyooka, Nami Kawaraichi, Daisuke Kamiya, Teruyoshi Yamashita, Yusaku Komoike, Kimiko Fukuda, Teppei Akaboshi, Hirokazu Matsumoto, Makoto Ikeya

Fibroblast-specific Deletion of Yap/Taz Impairs Mouse Postnatal Dermal Development by Suppressing Collagen Production and Deposition
Alexandre, Ava J Kim, Kirk C Hansen, Maxwell McCabe, Jun Young Kim, Zhaoping Qin, Zhaolin Zhang, Tianyuan He, Chunfang Guo, John J Voorhees, Gary J Fisher, Taihao Quan

Activation of developmental transcription factors using RNA technology promotes heart repair
Riley J. Leonard, Mason Sweat, Steven Eliason, William Kutschke, Brad A. Amendt

In vivo xenogenic reconstitution of human alveolar epithelial architecture and function
Akira Yamagata, Satoshi Konishi, Satoshi Ikeo, Hiroshi Moriyama, Senye Takahashi, Naoyuki Sone, Satoshi Hamada, Atsushi Saito, Takashi Kawaguchi, Shu Hisata, Akira Niwa, Toshiaki Kikuchi, Hirofumi Chiba, Megumu K. Saito, Koichi Hagiwara, Toyohiro Hirai, Mio Iwasaki, Takuya Yamamoto, Takeshi Takahashi, Shimpei Gotoh

PI3K inhibitor-free differentiation and maturation of human iPSC-derived arterial- and venous-like endothelial cells
Oliwia N. Mruk, Ralitsa R. Madsen

Scalable high-fidelity human vascularized cortical assembloids recapitulate neurovascular co-development and cell specialization
Shubhang Bhalla, Belda Gulsuyu, Damian Sanchez, Jayden M. Ross, Santhosh Arul, Adnan Gopinadhan, Muhammet Öztürk, Tanzila Mukhtar, Jonathan J. Augustin, Jerry C. Wang, Joseph Kim, Chang N. Kim, Sena Oten, Yohei Rosen, John M. Bernabei, Vijay Letchuman, Shantel Weinsheimer, Helen Kim, Elizabeth E. Crouch, Edward F. Chang, David Haussler, Mircea Teodorescu, Arnold R. Kriegstein, Tomasz J. Nowakowski, Ethan A. Winkler

Isthmin-1 is a Key Regulator of Induced Pluripotent Stem Cell–Derived Cardiomyocytes Maturation through Activation of p53 Signaling
Haowen Guo, Xin Zhou, Yang Shi, Bin Zhou, Jiaqi Tang, Faxiang Xu, Yanchen Guo, Fang Chen, Dongming Su, Qingguo Li

Cellular basis of accelerated whole-tooth regeneration
Talha Mubeen, Haowen He, George W. Gruenhagen, Anoushka Satoskar, Jeffrey T. Streelman

Identification of distinct functions of GLIS3 in β-cell generation critical to prevention of neonatal diabetes
David W. Scoville, Sara A. Grimm, Xin Xu, Benedict Anchang, Anton M. Jetten

Maternal lipids prime quiescent neural stem cells to reactivate in response to dietary nutrients
Md Ausrafuggaman Nahid, Susan E. Doyle, Kelly E. Dunham, Michelle L. Bland, Sarah E. Siegrist

Developmental programming of hematopoietic stem cell dormancy by evasion of Notch signaling
Patricia Herrero-Molinero, Eric Cantón, María Maqueda, Cristina Ruiz-Herguido, Arnau Iglesias, Jessica González, Brandon Hadland, Lluis Espinosa, Anna Bigas

Preconceptional immunomodulation partially corrects pregnancy abnormalities induced by endometriosis in a mouse model, with normalization of transcriptional alterations observed in the developing fetal-maternal interface at the single cell level
Kheira Bouzid, Roxane Bartkowski, Alix Silvert, Fabiana Moresi, Camille Souchet, Marine Thomas, Isabelle Lagoutte, Vaarany Karunanithy, Brigitte Izac, Charles Chapron, Pietro Santulli, Frédéric Batteux, Céline Mehats, Louis Marcellin, Ludivine Doridot

| Plant development

Novel repressors of cambium activity in Arabidopsis
Xing Wang, Jingyi Han, Emma K. Turley, Riikka Mäkilä, Anne-Maarit Bågman, Julia M. Kraus, Qing He, Hanan Alhowty, Joanna Edwards, Yuqi Li, Raluca Blasciuc, Wiktoria Fatz, Wenbin Wei, Miguel de Lucas, Siobhán M. Brady, Shixue Zheng, Chunli Chen, Ari Pekka Mäh-önen, J. Peter Etchells

AGP-Ca2+ binding is essential for pollen development and pollen tube growth in Arabidopsis thaliana
Jessy Silva, Maria João Ferreira, Paul Dupree, Matthew R. Tucker, Maria Manuela Ribeiro Costa, Sílvia Coimbra

Rewiring vascular patterning through translational control in Arabidopsis
Donghwi Ko, Raili Ruonala, Huili Liu, Ondrej Novak, Karin Ljung, Nuria De Diego, Robert Malinowski, Ykä Helariutta

Functional Redundancy of ZmSWEET6a/b in Mediating Sugar Transport and Redox Homeostasis for Maize Primexine Formation
Yan Zhang, Shuangtian Bi, Fengkun Sun, Jiajun Bu, Yurong Wang, Mateus Mondin, Zhaobin Dong, Weiwei Jin, Wei Huang

Arabidopsis GLK transcription factors interact with ABI4 to modulate cotyledon greening in light-exposed etiolated seedlings
Pengxin Yu, Friederike Saga, Miriam Bäumers, Ute Hoecker

Comprehensive characterisation of IAA inactivation pathways reveals the impact of glycosylation on auxin metabolism and plant development
Rubén Casanova-Sáez, Aleš Pěnčík, Federica Brunoni, Anita Ament, Pavel Hladík, Asta Žukauskaitė, Jan Šimura, Ute Voß, Ondřej Novák, Malcolm Bennett, Karin Ljung, Eduardo Mateo-Bonmatí

N-terminal phosphorylation inhibits Arabidopsis katanin and affects vegetative and reproductive development in opposite ways
Vivek Ambastha, Graham Burkart, Rachappa Balkunde, Ram Dixit

A conserved and predictable pluripotency window in callus unlocks efficient transformation in grasses and beyond
Yiyi Wang, Mengjiao Chu, Zhixia Wang, Jinhao Shao, Haijuan Zhang, Zhibiao Nan, Chunjie Li, Lei Lei

Two-step polar plastid migration via F-actin and microtubules ensures unequal inheritance during asymmetric division of Arabidopsis zygote
Keigo Tada, Hikari Matsumoto, Takao Oi, Zichen Kang, Tomonobu Nonoyama, Satoru Tsugawa, Yusuke Kimata, Shuhei Kusano, Shinya Hagihara, Shintaro Ichikawa, Yutaka Kodama, Minako Ueda

Ribosome profiling reveals distinct translational programs underlying Arabidopsis seed dormancy and germination
Maria Victoria Gomez Roldan, Elodie Layat, Julia Bailey-Serres, Jérémie Bazin, Christophe Bailly

Phosphovariants of the canonical heterotrimeric Gα protein, GPA1, differentially affect G protein activity and Arabidopsis development
David Chakravorty, Sarah M. Assmann

Wounding-Induced Redirection of Sugar Transport Fuels Tissue Repair
Rotem Matosevich, Mika Della Zuana, Itay Cohen, Idan Efroni

EARLY FLOWERING 3 (ELF3): a novel role in integrating environmental stimuli with root stem cell niche maintenance
Ali Eljebbawi, Rebecca C. Burkart, Laura Czempik, Vivien I. Strotmann, Xuelei Lai, Mark d. Tully, Luca Costa, Chloe Zubieta, Stephanie Hutin, Yvonne Stahl

The circadian clock gates lateral root development
Sota Nomoto, Allen Mamerto, Shiho Ueno, Akari E Maeda, Saori Kimura, Kosuke Mase, Ayano Kato, Takamasa Suzuki, Soichi Inagaki, Satomi Sakaoka, Norihito Nakamichi, Todd P. Michael, Hironaka Tsukagoshi

Initiation of asexual reproduction by the AP2/ERF gene GEMMIFER in Marchantia polymorpha
Go Takahashi, Saori Yamaya, Facundo Romani, Ignacy Bonter, Kimitsune Ishizaki, Masaki Shimamura, Tomohiro Kiyosue, Jim Haseloff, Yuki Hirakawa

A MICROTUBULE ASSOCIATED PROTEIN is required for division plane orientation during 3D-differential growth within a tissue
Zsófia Winter, Dorothee Stöckle, Takema Sasaki, Sophie Marc Martin, Yoshihisa Oda, Joop EM Vermeer

A shift in developmental allometry underlies the transition to a multi-ovulate strategy from a single-ovulate ancestral state in Phlox (Polemoniaceae)
Bridget Bickner, Elena M Kramer

Auxin coordinates cell states during Arabidopsis root development
Cassandra Maranas, Sydney VanGilder, Linda Nguyen, Jennifer Nemhauser

A chloroplast-localized protein AT4G33780 regulates Arabidopsis development and stress-associated responses
Zhengchao Yang, Zhiming Yu

Root-Suppressed Phenotype of Tomato Rs Mutant is Seemingly Related to Expression of Root-Meristem-Specific Sulfotransferases
Alka Kumari, Prateek Gupta, Parankusam Santisree, Injangbuanang Pamei, Satyavati Valluri, Kapil Sharma, Kavuri Venkateswara Rao, Shivani Shukla, Srilatha Nama, Yellamaraju Sreelakshmi, Rameshwar Sharma

| Environment, evolution and development

Programming of Embryonic Blood Brain Barrier and Neurovascular Transcriptome by an Anticipatory Acoustic Signal of Heat in the Zebra Finch
Prakrit Subba, Mylene M. Mariette, Katerina A. Palios, Michael G. Emmerson, Elisabetta Versace, Katherine L. Buchanan, David F. Clayton, Julia M. George

Developmental Hypoxia Increases Susceptibility to Cardiac Ventricular Arrhythmias in Adult Offspring
Mitchell C Lock, Kerri LM Smith, Aga Swiderska, Hayat Baba, Andrew Silverwood, Julia Dyba, Olga V Patey, Youguo Niu, Sage G Ford, Freja Steinke, Katherine Dibb, Andrew W Trafford, Dino A Giussani, Gina LJ Galli

Hypoxia couples growth and developmental timing by decoupling steroid synthesis and secretion
George P. Kapali, Alexander W. Shingleton

Early exposure to PFAS disrupts neuro-muscular development in zebrafish embryos
Zainab Afzal, Brian N. Papas, Vandana Veershetty, Evan E Pittman, Charles Hatcher, Jian-Liang Li, Warren Casey, Deepak Kumar

In vitro sexual dimorphism establishment in schistosomes
Remi Pichon, Magda E Lotkowska, Jude L. D. Bulathsinghalage, Madeleine McMath, Mary Evans, Benjamin J. Hulme, Kirsty Ambridge, Geetha Sankaranarayanan, Simon Kershenbaum, Sarah D. Davey, Josephine E. Forde-Thomas, Karl F. Hoffmann, Matthew Berriman, Gabriel Rinaldi

Maternal cardiometabolic dysfunction and fetal sex-specific alterations to uterine vascular reactivity in an ovine model of diet-induced obesity during pregnancy
Rachael C. Crew, Anna L.K. Cochrane, Youguo Niu, Sage G. Ford, Clement L.R. Cahen, Skaai H. Davison, Michael P. Murphy, Susan E. Ozanne, Dino A. Giussani

Prenatal Exposure to Bacterial Extracellular Vesicles Influences Fetal Gut Immunity and Immune Programming
Manuel S. Vidal, Ananth Kumar Kammala, Madhuri Tatiparthy, Ryan C. V. Lintao, Rahul Cherukuri, Ourlad Azeleus Tantengco, Shelly A. Buffington, Enkhtuya Radnaa, Lauren S. Richardson, Ramkumar Menon

Evolutionary dynamics of temporal transcription factor series in the insect optic lobe
Konstantina Filippopoulou, Elisavet Iliopoulou, Claire Julliot de La Morandière, Christy Lee, Marina Marcet-Houben, Toni Gabaldón, Jingyi Jessica Li, Nikolaos Konstantinides

lncRNAs contribute to caste differentiation as a regulatory layer in ants
Guo Ding, Fuqiang Lin, Jixuan Zheng, Dashuang Zuo, Zijun Xiong, Chenyan Liao, Bitao Qiu, Wenjiang Zhong, Jie Zhao, Weiwei Liu, Guojie Zhang

Sex chromosomes and sex hormones contribute jointly and independently to sex biases in cardiac development
Daniel F. Deegan, Gennaro Calendo, Priya Nigam, Raza Naqvi, Arthur P. Arnold, Nora Engel

Cell Biology

Mechanically competitive regulation of cell volume in cytoplasm-sharing cells connected by intercellular bridges
Hiroshi Koyama, Kanako Ikami, Lei Lei, Toshihiko Fujimori

Interface-Resolved Proteomics of Cell–Cell Membranes Reveals Early Spatial Polarity in a Vertebrate Embryo
Fei Zhou, Peter Nemes

Direct labeling of microtubule turnover reveals in-lattice repair and stabilization patterns in developing neurons
Ciarán Butler-Hallissey, Harrison M. York, Florence Pelletier, Jean-Marc Goaillard, Jérémie Gaillard, Manuel Théry, Pascal Verdier-Pinard, Christophe Leterrier

C. elegans E3 ubiquitin ligase EBAX-1 promotes non-apoptotic linker cell-type death through target-directed miRNA degradation
Lauren B. Horowitz, Olya Yarychkivska, Yun Lu, Shai Shaham

Kinesin-1 trans-synaptically regulates synaptic localization of SARM1 for asymmetric neuron diversification
Anaam Khalid, Peter Sahyouni, Jun Yang, Shengyao Yuan, Rui Xiong, Chiou-Fen Chuang

Lysosome-Related Organelles Orchestrate Guanine Crystal Formation in Pigment Cells
Anna Gorelick-Ashkenazi, Yuval Barzilay, Tali Lerer-Goldshtein, Tsviya Olender, Zohar Eyal, May Glaser, Yonatan Broder, Nadav Mishol, Rachael Deis, Merav Kedmi, Dvir Gur

P-glycoprotein exofection between fetal and maternal cells as a mechanism of intercellular material transfer at the feto maternal interface
Madhuri Tatiparthy, Amanda Wang, Vineeth Mahajan, Pilar Flores-Espinosa, Emmanuel Amabebe, Tilu Jain Thomas, Xiao-Ming Wang, Lauren S Richardson, Ramkumar Menon, Ananth K Kammala

Modelling

Clocks and Dominoes: Timing Mechanisms of Embryogenesis
Yonghyun Song, Brian D. Leahy, Hanspeter Pfister, Dalit Ben-Yosef, Daniel J. Needleman

Integrative Inference of Spatially Resolved Cell Lineage Trees using LineageMap
Xinhai Pan, Yiru Chen, Xiuwei Zhang

A proteomic signature of oocyte quality from models of varying oocyte developmental competence
Emily R. Frost, Dulama Richani, Anne Poljak, Ananya Vuyyuru, Xuihua Liao, Elise Georgiou, J M Binuri Gunasekara, Bettina P. Mihalas, Irene E. Sucquart, Kaushiki Kadam, Lindsay E. Wu, Robert B. Gilchrist

MorphoLearn: A morphology-driven workflow to decipher 3D electron microscopy segmentation in diatoms
Clarisse Uwizeye, Serena Flori, Jhoanell Angulo, Pierre-Henri Jouneau, Benoit Gallet, Pascal Albanese, Giovanni Finazzi

How simple physics drives the earliest stages of embryogenesisAlaina Cockerell, Peyman Shadmani, Krasimira Tsaneva-Atanasova, David M. Richards

Early multi-omic signatures and machine learning models predict cardiomyocyte differentiation efficiency and enable robust hPSC differentiation to cardiomyocytesAustin K. Feeney, Aaron D. Simmons, Elizabeth F. Bayne, Yanlong Zhu, Mason R. Pentes, Paulo F. Cobra, Jianhua Zhang, Timothy J. Kamp, Ying Ge, Sean P. Palecek

Tools & Resources

Establishing genetically controlled, closed colonies of an ascidian
The Ciona bio-resource consortium

HoloBio A Holographic Microscopy Tool for Quantitative Biological Analysis
Waira Mona, Maria J. Gil-Herrera, Emanuel Mazo, Daniel Córdoba, Sofia Obando, Maria J. Lopera, Rene Restrepo, Carlos Trujillo, Ana Doblas, Raul Castaneda

Array-CNCC: precise aggregation and arrayed plating facilitate quantitative phenotyping of human cranial neural crest cells and craniofacial disease modelling
Ewa Ozga, Katarzyna M Milto, Martina Demurtas, Lawrence E Bates, Graeme Grimes, Takuya Azami, Jing Su, Carlo De Angelis, Marco Trizzino, Jennifer Nichols, Hannah K Long

Sixteen isotropic 3D fluorescence live imaging datasets of Tribolium castaneum gastrulation
Franziska Krämer, Stefan Münster, Frederic Strobl

Integration of early-stage cryopreservation and cell cycle modulation into a flexible kidney organoid differentiation system
Xiaotian Yan, Jina Wang, Ming Xu, Chunlan Hu, Siyue Chen, Yufeng Zhao, Jiyan Wang, Ruiming Rong, Tongyu Zhu, Weitao Zhang

A robust human airway organoid platform enables scalable expansion and trajectory mapping of pulmonary neuroendocrine cells
Noah Candeli, Lisanne den Hartigh, Nicholas Hou, Andrés Marco, José Antonio Sánchez-Villacaña, Andrea Garcia-Gonzales, Shashank Gandhi, Francesca Sgualdino, Alyssa J. Miller, Jason Spence, Susana Chuva de Sousa Lopes, José L. McFaline-Figueroa, Hans Clevers, Talya L. Dayton

“All-in-one” Single-Cell Proteomic Analysis of Protein Alterations in Human Oocytes Undergoing in Vitro Aging
Jue Zhang, Yuting Lu, Shuoping Zhang, Xingyao Wang, Jiao Lei, Feitai Tang, Shen Zhang, Ge Lin

Real-time single-molecule imaging in zebrafish embryos uncovers non-canonical translation
Maëlle Bellec, Kenny Mattonet, Tatsuya Morisaki, Margaux Lay, Jie Liang, Damien Avinens, Vincent Martinet, Delphine Muriaux, Timothy J Stasevich, Jérémy Dufourt, Didier Y R Stainier

Integration of in situ hybridization and scRNA-seq data provides a 2D topographical map of the developing retina across species
Heer N. V. Joisher, ChangHee Lee, Chaitra Prabhakara, Isabella van der Weide, Yichen Si, Nicholas Lonfat, Constance Cepko

Research practice & education

Development and field test of an intervention to reduce conflict in faculty-doctoral student mentoring relationships
Trevor T. Tuma, Emily Q. Rosenzweig, Justin A. Lavner, Yichi Zhang, Erin L. Dolan

Collective AI use is associated with researcher engagement: Real-time evidence from a scientific conference
Hiroyuki Okada, Shigeto Seno, Ung-il Chung, Naganari Okura

The Demographic and GDP Impacts of Slowing Biological Aging
Raiany Romanni-Klein, Nathaniel Hendrix, Richard W. Evans, Jason DeBacker

Leveraging a hybrid cross-disciplinary training model to accelerate global bioinformatics capacity
Taras K. Oleksyk, Daryna Yakymenko, Sylwia Bożek, Viorel Munteanu, Wojciech Pilch, Zoia Comarova, Victor Gordeev, Grigore Boldirev, Dumitru Ciorbă, Viorel Bostan, Christopher E. Mason, Alexander G. Lucaci, Nadiia Kasianchuk, Daria Nishchenko, Victoria Popic, Andrei Lobiuc, Mihai Covasa, Martin Hölzer, Joanna Polanska, Alex Zelikovsky, Vasili Braga, Mihai Dimian, Paweł Łabaj, Serghei Mangul

Cloud-Connected Pluripotent Stem Cell Platform Enhances Scientific Identity in Underrepresented Students
Samira Vera-Choqqueccota, Drew Ehrlich, Vladimir Luna-Gomez, Sebastian Hernandez, Jesus Gonzalez-Ferrer, Hunter E. Schweiger, Kateryna Voitiuk, Yohei Rosen, Kivilcim Doganyigit, Isabel Cline, Rebecca Ward, Erika Yeh, Karen H. Miga, Barbara Des Rochers, Sri Kurniawan, David Haussler, Kristian López Vargas, Mircea Teodorescu, Mohammed A. Mostajo-Radji

Beyond Deficit and Coexistence: Modeling the Knowledge–Conspiracy–Mistrust Configuration in Public Understanding of Science
Ahmet Süerdem, Svetlomir Zdravkov, Martin J. Ivanov

Uncovering Conceptual Biases in DNA Stabilization: A Student-Led Investigation
Charlotte Polo, Ameeta Thandi, Olivia Chandler, Paula Lugert, Alyssa Hammoud, Theertha Madhi, Malena Ayala, A.J. Berrigan, Andrew Chen, Kate Gillett, Sohan Sanjeev, Mya Sareen, Sean Yu, Yang-yang Zuo, Shawn Xiong

Fine-Grained Detection of AI-Generated Writing in the Biomedical Literature
Richard She

(No Ratings Yet)
Loading...