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FocalPlane: a new microscopy community site from The Company of Biologists

Posted by on July 2nd, 2020

FocalPlane is a new microscopy community site hosted by Journal of Cell Science (JCS), Development’s sister journal, and like the Node funded by our not-for-profit publisher, The Company of Biologists. Launched yesterday, it encompasses all fields in the biological sciences where they meet microscopy. Here the FocalPlane team introduce the site: From conversations the JCS[…]

Survey about online seminars & conferences

Posted by on June 23rd, 2020

The ongoing pandemic has resulted in many scientific conferences moving to an online format, and researchers who can no longer attend seminars at their institutes have been organising and attending various virtual seminar series (here on The Node there are currently over 40 online events listed in developmental biology and beyond). Several considerations about virtual[…]

Research Highlight #5: Leukemic stem cells from iPSCs

Posted by on June 9th, 2020

Today let’s delve into a curious case involving induced pluripotent stem cells (iPSCs) and leukemic stem cells (LSCs). Most blood cells derived from iPSCs are unable to engraft in immunodeficient mice. However, Wesely and colleagues observed an exceptionally high engraftment efficiency of cell lines derived from an individual affected by acute myeloid leukemia (AML). In[…]

Research Highlight #4: Macrophages in human development

Posted by on June 1st, 2020

Today we return our interest to human development, focusing on a special blood cell: the macrophage. Produced in multiple, stem cell-independent waves, macrophages colonize the developing foetus early on, forming several tissue-resident populations. This includes the microglia which are essential for brain and spinal cord development. In this paper, the authors looked into macrophage development[…]

Research Highlight #3: IL-1 regulates haematopoietic stem cell pool size via PU.1

Posted by on May 25th, 2020

Today, we move to mouse adult haematopoiesis, with an elegant work on inflammation and stem cell biology. As always, feedback is more than welcome! Chronic inflammation is one of the classic events underlying aging and infection response. When associated with loss of quiescence in haematopoietic stem cells (HSCs), it is commonly the initiating event in[…]

Staying connected during the COVID19 pandemic

Posted by on May 21st, 2020

Among many other (many more important) things, pandemic times have meant an end to travel, which for the Development team means no conferences and no lab visits. For me personally, it’s meant cancelled trips to Shanghai, Kyoto, Washington and Chicago, and while I’m delighted to be keeping my carbon footprint down, I’m definitely missing the[…]

Last chance to take our user survey

Posted by on May 19th, 2020

We’ve had a great response so far to our tenth birthday user survey, which we hope will guide us going forwards and give us ideas for how we can better serve the developmental biology and stem cell community. If you haven’t taken it yet, it closes Thursday midday BST. Even if you’re a less-than-occasional reader,[…]

Call for papers

Posted by on May 12th, 2020

Chan, Z., Santella, L., Tuszynski, J. and Gordon, R. (eds.) (2020) Waves in Fertilization, Cell Division and Embryogenesis [special issue of BioSystems, In preparation] [WAVS].   Deadline changed to March 31, 2021 due to COVID-19. Papers will be published when approved. (No Ratings Yet)Loading…

An update from Development

Posted by on May 11th, 2020

I wanted to take a couple of minutes to update you on how things are going at Development. I imagine many of you will be reading this on a laptop in your home office/kitchen/bedroom in between Zoom calls, homeschooling and/or sourdough baking. In much of Europe and North America, as well as other parts of[…]

JoVE for developmental biology research and eduction

Posted by on April 24th, 2020

Dear Developmental Biologists, We would like to take this opportunity to thank the Node for the chance to write a post about JoVE and how our resources can be beneficial for the research and teaching of developmental biology and multiple other disciplines. All researchers will be familiar with the challenges of replicating an experiment you’ve[…]