developmental and stem cell biologists
Posted by the Node Interviews, on 22 May 2018
The vertebrate lymphatic vascular network provides crucial circulatory and immune functions but its developmental origin has been a contentious issue, in particular the question of whether lymphatic endothelial cells have ...Posted by the Node Interviews, on 21 May 2018
Intrahepatic bile ducts (IHBDs) are epithelial tubular structures that transport bile from the liver to the intestine, but the molecules and mechanisms controlling IHBD morphogenesis have remained largely unclear. A a ...Posted by the Node Interviews, on 19 April 2018
The transition to multicellularity in eukaryotes appears to be intimately linked to the transition from isogamy (gametes of the same size) to anisogamy (gametes of distinct sizes), and indeed to ...Posted by the Node Interviews, on 9 April 2018
Cell fate commitment relies on both activation of appropriate genes and suppression of inappropriate ones. Polycomb group proteins are known to be crucial epigenetic silencers of developmental genes, but the ...Posted by the Node Interviews, on 5 April 2018
Development and homeostasis depend crucially on the maintenance of cell identity, and in gamete-producing tissues the somatic/germline distinction is paramount. A recent paper in Development explores how cell identity is ...