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developmental and stem cell biologists
Posted by the Node Interviews, on 13 April 2017
In spite of our external appearance, our innards are asymmetric. For today’s interview, we feature a paper published recently in Development that provides a cellular and molecular investigation into symmetry breaking in a poorly understood ...Posted by the Node Interviews, on 7 April 2017
Macrophages are usually associated with immunity, but have increasingly appreciated functions in development and homeostasis. This week we meet the authors of a recent Science paper that identified a role ...Posted by the Node Interviews, on 30 March 2017
This year marks the centenary of D’Arcy Thompson’s On Growth and Form, an attempt to outline the physical and mathematical principles underpinning the generation of biological form. Modern day developmental biologists, ...Posted by the Node Interviews, on 21 February 2017
Conjoined twins have fascinated biologists for centuries. In twins joined at the thorax, left-right patterning is disrupted, but only in one half of the right hand twins. Today’s paper, from ...Posted by the Node Interviews, on 15 February 2017
Embryonic stem cells express genes necessary for self-renewal, and also ‘prime’ lineage-specific genes which stay silent until differentiation; the molecular players and pathways that govern the timely gene expression are still being ...Posted by the Node Interviews, on 8 February 2017
Radial glial cells are multipotent progenitors in the developing vertebrate brain. At their apical interface with the ventricular cavity around which the brain forms, they bear a primary cilium, a signalling ...Posted by the Node Interviews, on 1 February 2017
The brown alga Ectocarpus has emerged as a model system for the evolution of muticellularity. Today’s paper, from the current issue of Development, investigates the role and evolutionary history of a gene implicated ...Posted by the Node Interviews, on 25 January 2017
How does a developing embryo coordinate DNA replication with gene transcription? This fundamental question is the focus of today’s paper, recently published in eLife. We caught up with lead author Ehsan Pourkarimi ...Posted by the Node Interviews, on 4 January 2017
The tenth paper featured in this series comes from the first issue of Development for 2017, and uses computational modelling to investigate the importance of different cellular processes in spiral ...Posted by the Node Interviews, on 16 December 2016
The neural crest is a remarkable multipotent cell population that has become a model system for how epithelial cells become mesenchymal and migrate during development. In today’s post, we feature ...