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Displaying posts in the category: Research

Of Arms and Legs: Shedding light onto developmental gene regulation

Posted by , on 19 November 2018

Written and illustrated by: Bjørt K. Kragesteen, Malte Spielmann, and Guillaume Andrey.   In early development, the forelimb and hindlimb buds of tetrapods are morphologically uniform. However, as limb development ...

Wire together, remodel together

Posted by , on 15 November 2018

Newborn babies are a symbol of immense potential, as they can grow up to be become virtually anybody, from an astronaut to the president. It is no secret that throughout ...

Sex combs in motion

Posted by , on 14 November 2018

Using computer simulations and mathematical modeling to study the evolution of morphogenesis   Juan N. Malagon and Ernest Ho tell the story behind their recent paper in PLOS Computational Biology. In ...

Alan Turing’s patterning system can explain the arrangement of shark scales

Posted by , on 7 November 2018

Understanding how complex biological patterns arise is a long standing and fascinating area of scientific research. The patterning, or spatial arrangement, of vertebrate skin appendages (such as feathers, hair and ...

Frog legs: they’re smarter than they look!

Posted by , on 22 October 2018

By Sera Moon Busse Studying limb regeneration in model organisms is important for the advancement of regenerative medicine in humans. We set out to study regeneration in the hind limbs ...

Scaling the Fish: An L.A. Story

Posted by , on 18 October 2018

Jeff Rasmussen tells the story behind his recent paper from the Sagasti Lab in Dev Cell. This project began as an extension of my earlier postdoc work in Alvaro Sagasti’s ...

Spider segmentation gets its SOX on!

Posted by , on 15 October 2018

There is a vast amount of information known about how some animals pattern their bodies into repeated segments, especially in the fruit-fly Drosophila melanogaster. However, when compared to other arthropods, ...

Post-doctoral position in pancreatic tissue engineering available in the Spagnoli lab.

Posted by , on 12 October 2018

A Postdoctoral position is available in the Spagnoli lab. in the Centre for Stem Cell and Regenerative Medicine at King’s College, London. Our team uses interdisciplinary approaches to study pancreas ...

Make a difference: the alternative for p-values

Posted by , on 8 October 2018

Calculation and reporting of p-values is common in scientific publications and presentations (Cristea and Ioannidis, 2018). Usually, the p-value is calculated to decide whether two conditions, e.g. control and treatment, ...

Staying in shape

Posted by , on 5 October 2018

If you’re into developmental biology, chances are you’ve spent some time in your life thinking about how cells change the shapes of tissues. What would cells need to do in ...

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