CoB Workshop: Epigenetic Memory Day 3
Posted by Emmanuelle Vire, on 27 June 2012
Tuesday, third day of the workshop, brings up more arguments to the epigenetic memory debate. Alyson Ashe from Cambridge UK discussed the establishment and maintenance of silencing through generations in worms. Jonathan Chubb presented his work using Dictyostelium and live imaging to investigate pulses of expression and how it relates to epigenetic memory. Neil Brockdorff and Andy Bannister discussed histone modifications and their involvement in chromatin and transcriptional regulation (X inactivation and cancers respectively). Fantastic chunky chips for lunch and delicious Eton mess gave everyone the energy to carry on discussing the existence of early events in reprogramming (Amanda Fisher), X-inactivation in mouse embryos (Atsuo Ogura) and how cell type specificity is kept through mitosis. The workshop atmosphere resembles a chamber music session : epigenetic players take part in a very special session to write a new concerto. The interpretation of the music, however, can also generate few dissonances.