the community site for and by
developmental and stem cell biologists

December 17

Posted by , on 17 December 2012

Today’s recommended paper is:

A system of repressor gradients spatially organizes the boundaries of Bicoid-dependent target genes.
Hongtao Chen, Zhe Xu, Constance Mei, Danyang Yu and Stephen Small (2012)
Cell 149 (3), 618-629

Submitted twice – by Andrew Renault and by Seema Grewal.

Andrew: “How morphogens create robust and discrete responses has been a long standing question. This paper nicely shows that the correct order of Bicoid target gene boundaries depends on a system of transcriptional repressors, reinforcing the notion that antagonistic mechanisms are critical for morphogen function”

Seema: “This paper challenges the idea that Bicoid acts as a simple morphogen.”

 

From December 1 to 24 we are featuring Node readers’ favourite papers of the past year. Click the calendar in the side bar each day to see a new paper. To see all papers submitted so far, see the calendar archive.

Thumbs up (1 votes)
Loading...

Tags:
Categories: Research

Leave a Reply

Your email address will not be published. Required fields are marked *

Get involved

Create an account or log in to post your story on the Node.

Sign up for emails

Subscribe to our mailing lists.

Do you have any news to share?

Our ‘Developing news’ posts celebrate the various achievements of the people in the developmental and stem cell biology community. Let us know if you would like to share some news.