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Genetics Unzipped podcast: Six toed cats and cyclops lambs – the story of Sonic Hedgehog

Posted by , on 1 July 2021

A six toed cat
Hemingway House six toed cat, by Reyvato, CC BY-SA 3.0 via Wikimedia Commons

In this episode of Genetics Unzipped, supported by the Institute of Genetics and Cancer at the University of Edinburgh, Kat Arney sits down with Professor Bob Hill to take a look at the story of our favourite gene (we’ve all got one, right?).

From six-toed cats to cyclops lambs – and, of course, it’s fabulous name – the Sonic Hedgehog gene has a fascinating history, as well as a whole bunch of interesting developmental biology behind it. 

Genetics Unzipped is the podcast from The Genetics Society. Full transcript, links and references available online at

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